Breast biopsy -Medium 1-3 cm
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To identify cancerous, precancerous, or non-cancerous changes
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🔬 Breast Biopsy – Medium (1–3 cm lesion)
Parameter | Details |
|---|---|
Test Name | Breast Biopsy – Medium Size (1–3 cm lesion) |
Sample Type | Solid breast tissue (via needle/core/incisional biopsy) |
Fasting Required | ❌ Not required (unless general anesthesia is used) |
Organ | Breast (mammary tissue) |
Purpose | To determine if a suspicious breast lump or lesion is benign or malignant |
🧬 What Is a Breast Biopsy?
A breast biopsy is a diagnostic procedure to remove tissue from a suspicious lump or abnormal area in the breast, often identified by:
- Mammogram
- Ultrasound
- Physical examination
The extracted tissue is examined under a microscope to identify cancerous, precancerous, or non-cancerous changes.
🔍 Common Indications
- Breast lump or nodule (1–3 cm in this case)
- Abnormal mammogram/ultrasound findings (e.g., mass, calcifications)
- Nipple discharge (bloody/clear)
- Skin changes over the breast
- Family history of breast cancer
🧪 Types of Breast Biopsies
Type | Details |
|---|---|
Core Needle Biopsy (CNB) | Most common for 1–3 cm lesions; local anesthesia; tissue cores taken |
Fine Needle Aspiration (FNA) | Less tissue obtained, used for cystic lesions; less accurate |
Excisional Biopsy | Entire lump removed surgically, usually for diagnosis or removal |
Incisional Biopsy | Only a portion of larger mass removed for diagnosis |
Stereotactic/Ultrasound-guided | Used for non-palpable or deep lesions guided by imaging |
🔬 Histopathological Evaluation
The tissue is tested for:
Marker/Test | Purpose |
|---|---|
Histology | Cancer type (ductal/lobular, invasive/in situ) |
ER/PR Receptors | Estrogen and progesterone sensitivity |
HER2/neu | Predicts aggressiveness and eligibility for Herceptin |
Ki-67 | Proliferation index – how fast the tumor is growing |
Lymphovascular Invasion | Spread to surrounding vessels |
Margins | For excisional biopsies – whether cancer reaches the edge |
🧠 Interpretation
Finding | Likely Diagnosis |
|---|---|
Fibroadenoma | Benign tumor; common in young women |
Fibrocystic changes | Benign, hormonal breast condition |
Ductal Carcinoma In Situ (DCIS) | Non-invasive, early-stage cancer |
Invasive Ductal Carcinoma | Most common type of breast cancer |
Lobular Carcinoma | Less common, can be bilateral |
Inflammatory/Phyllodes Tumor | Rare tumors with different growth patterns |
🔗 Further Recommended Diagnostics
Test | Purpose |
|---|---|
Mammography | Screening and follow-up of other lesions |
Breast Ultrasound | Imaging guidance for deeper or cystic lesions |
MRI Breast | High-risk patients or dense breast tissue |
PET/CT Scan | If cancer is confirmed, for staging |
Liver function tests & CBC | To assess for metastasis or pre-surgical fitness |
BRCA1/BRCA2 Genetic Testing | If family history or young age |
🧾 Summary Table
Parameter | Breast Biopsy – Medium Lesion (1–3 cm) |
|---|---|
Type | Usually Core Needle Biopsy or Image-guided biopsy |
Target | Lesions 1–3 cm identified via palpation or imaging |
Purpose | Diagnose cancer, benign tumors, or atypical changes |
Next Steps | Histopathology, receptor testing, and staging if malignant |
How our test process works!
