Breast biopsy -small <1cm
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To determine if a small breast lesion is benign or malignant
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🔬 Breast Biopsy – Small Lesion (<1 cm)
Parameter | Details |
|---|---|
Test Name | Breast Biopsy – Small Size Lesion (<1 cm) |
Sample Type | Breast tissue (collected via minimally invasive biopsy) |
Fasting Required | ❌ Not needed (unless general anesthesia used, rarely) |
Organ | Breast |
Purpose | To determine if a small breast lesion is benign or malignant |
🧬 What is This Test?
A breast biopsy involves collecting tissue from a small, suspicious breast mass (<1 cm) for microscopic examination. The goal is to:
- Identify whether the mass is cancerous, precancerous, or benign
- Detect early breast cancer (especially non-palpable lesions)
Such small lesions are often detected incidentally on mammogram or breast ultrasound during routine screening.
🧪 Preferred Techniques for <1 cm Lesions
Biopsy Type | Best Suited For |
|---|---|
Stereotactic Needle Biopsy | For non-palpable lesions seen on mammogram |
Ultrasound-guided Core Biopsy | For lesions visualized on USG; commonly used in India |
Vacuum-Assisted Biopsy | Can remove more tissue from very small lesions |
Fine Needle Aspiration (FNA) | Occasionally used for cystic or easily accessible small lumps |
These techniques are minimally invasive, often done under local anesthesia, and leave only a tiny scar.
🧫 Histopathological Evaluation Includes
Test | Purpose |
|---|---|
Histology | Cancer vs benign lesion (e.g. fibroadenoma, papilloma) |
ER/PR Receptor Status | Determines hormone sensitivity |
HER2/neu | Predicts aggressiveness and targeted therapy |
Ki-67 Index | Tumor growth rate |
Margins | In excision, whether the tumor is completely removed |
🔍 Clinical Conditions Detected
Diagnosis | Notes |
|---|---|
Fibroadenoma | Benign, common in young women |
Papilloma or Sclerosing Adenosis | Benign but may mimic malignancy |
DCIS (Ductal Carcinoma In Situ) | Early-stage, non-invasive cancer |
Invasive Ductal/Lobular Carcinoma | Malignant, requires further staging and treatment |
Atypical Hyperplasia | Pre-cancerous; may need monitoring or surgery |
🩺 Why Early Biopsy Matters (<1 cm)
- High cure rate if cancer is detected early
- Smaller size often means localized, not spread
- Enables breast-conserving therapy or minimal surgery
- Helps avoid delayed diagnosis in high-risk patients
🧪 Further Recommended Diagnostics
Test | Purpose |
|---|---|
Mammography / Digital Breast Tomosynthesis | Evaluate surrounding tissue |
Breast Ultrasound | Characterize the lesion further |
MRI Breast | In dense breast or strong family history |
Tumor Marker Panel (CA15.3, CEA) | For monitoring if cancer is detected |
Genetic Testing (BRCA1/2) | If patient is <40 or with strong family history |
Complete Blood Count & LFT | Baseline for any therapy planning |
📋 Summary Table
Biopsy Size Category | Small Breast Lesion Biopsy (<1 cm) |
|---|---|
Techniques Used | Ultrasound-guided core biopsy, stereotactic, vacuum biopsy |
Purpose | Confirm or rule out malignancy in early/small lesions |
Best for | Screen-detected, non-palpable nodules |
Advantages | Minimally invasive, early diagnosis, high accuracy |
Next Steps (if cancer) | Receptor analysis, imaging, oncologist referral |
How our test process works!
