Cervix biopsy -small <1cm
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Evaluation of abnormal Pap smear, diagnosis of precancerous or cancerous lesions
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🧬 Cervix Biopsy – Small (<1 cm)
Parameter | Details |
|---|---|
Sample Type | Cervical tissue biopsy (<1 cm) |
Fasting Required | ❌ Not required |
Organ Involved | Cervix (lower portion of uterus, opening into vagina) |
Primary Use | Histopathological diagnosis of precancerous changes, infection, or early cervical cancer |
Department | Gynecology / Oncology / Histopathology |
🔍 Purpose of Cervix Biopsy (Small)
This test is usually done after:
- Abnormal Pap smear results
- Persistent HPV infection
- Suspicion of Cervical Intraepithelial Neoplasia (CIN)
- Post-coital bleeding, chronic discharge, or visible lesions
A small biopsy (<1 cm) is often taken during colposcopy-guided punch biopsy for diagnosis, especially when the lesion is localized.
🧪 Conditions Detected
Condition | Explanation |
|---|---|
CIN I / CIN II / CIN III | Grades of precancerous dysplasia |
Chronic Cervicitis | Inflammatory condition due to infection or irritation |
Squamous Cell Carcinoma (Early) | Early-stage cervical cancer |
HPV-related cellular changes | Koilocytosis, dyskaryosis |
Cervical Polyps / Ectropion | Benign lesions often causing discharge or bleeding |
Granulomatous inflammation | Rare, but possible in TB-endemic areas |
🧬 When is it Recommended?
- Positive HPV DNA Test (High-Risk HPV strains)
- ASC-US / LSIL / HSIL on Pap smear
- Bleeding after sex or between periods
- Visible lesion on cervix during pelvic exam or colposcopy
- Unexplained pelvic pain or chronic discharge
🔬 Histopathology Insights
The report typically mentions:
- Type of epithelium involved (squamous, glandular)
- Grade of dysplasia if any
- Presence of invasion (if cancerous)
- Inflammatory or infectious changes
🧪 Further Diagnostic Tests (If Indicated)
Test | Purpose |
|---|---|
HPV DNA Genotyping | Identifies high-risk viral subtypes (e.g., HPV 16, 18) |
Pap Smear / LBC | Cervical cytology for dysplasia detection |
Colposcopy | Magnified inspection and mapping of lesion |
Endocervical Curettage (ECC) | If lesion not visible externally |
Immunostaining (p16, Ki-67) | Marker of HPV-related high-grade dysplasia |
STD Panel / HIV Test | Rule out co-infections, esp. in immunocompromised women |
📋 Summary
Test Name | Cervix Biopsy – Small (<1 cm) |
|---|---|
Organ | Cervix |
Sample Type | Small tissue (<1 cm) from abnormal area |
Fasting Required | No |
Use | Diagnosis of CIN, chronic cervicitis, early carcinoma |
Next Steps if Positive | Cone biopsy, LEEP, HPV subtyping, oncology referral |
How our test process works!
