Cheek biopsy -small <1cm
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Evaluation of suspicious lesions, oral ulcers, leukoplakia, or oral cancer
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🧬 Cheek Biopsy – Small (<1 cm)
Parameter | Details |
|---|---|
Sample Type | Buccal (cheek mucosa) tissue <1 cm in size |
Fasting Required | ❌ Not required |
Organ Involved | Buccal mucosa (inner lining of the cheek) |
Primary Use | Evaluation of suspicious lesions, oral ulcers, leukoplakia, or oral cancer |
Department | ENT / Oral & Maxillofacial Surgery / Histopathology |
🔍 Why is a Cheek Biopsy Done?
A cheek biopsy helps identify:
- Precancerous changes or early oral cancer
- Persistent non-healing ulcers or red/white patches
- Suspicious growths, thickenings, or plaques
- Chronic infections like oral lichen planus or candidiasis
- Autoimmune or inflammatory conditions (e.g., pemphigus, lupus)
⚕️ Common Indications
Condition | Explanation |
|---|---|
Leukoplakia / Erythroplakia | White or red patches with potential for malignant transformation |
Oral Squamous Cell Carcinoma | Most common type of oral cancer |
Lichen Planus | Chronic inflammatory condition causing white striations or erosions |
Pemphigus Vulgaris | Autoimmune blistering disease affecting oral mucosa |
Chronic Candidiasis | Persistent fungal infection |
Oral Submucous Fibrosis | Fibrotic thickening of mucosa (often due to tobacco/betel nut use) |
🔬 Histopathology Insights
The biopsy is evaluated for:
- Dysplastic changes
- Malignant cells
- Epithelial hyperplasia or atrophy
- Inflammation or fungal elements
- Autoimmune markers (e.g., acantholysis in pemphigus)
🧪 Tests Often Done Along With Cheek Biopsy
Test | Purpose |
|---|---|
Brush Cytology / Oral Smear | Preliminary screening for dysplastic cells |
Fungal Culture or KOH Prep | Rule out oral candidiasis |
Direct Immunofluorescence (DIF) | In autoimmune blistering disorders |
HPV Typing (if suspected) | HPV-related oral lesions |
Complete Blood Count (CBC) | To check for anemia, infections |
Vitamin B12 & Folate | Rule out nutritional causes of mouth ulcers |
📋 Summary
Test | Cheek Biopsy – Small (<1 cm) |
|---|---|
Organ | Buccal mucosa (inner cheek) |
Sample Type | Small incisional/punch biopsy |
Use | Detect oral cancer, inflammation, infection, autoimmunity |
Reported By | Histopathologist |
Next Steps if Positive | Further imaging (CT/MRI), wide excision, oncology referral |
How our test process works!
