HELICOBACTER PYLORI - IgG (CLIA)
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Detects the presence of IgA antibodies against H. pylori bacteria in the blood using the CLIA method
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🧪 What is Helicobacter pylori – IgG (CLIA)?
Helicobacter pylori – IgG (CLIA) is a blood test that detects IgG antibodies against Helicobacter pylori using CLIA (Chemiluminescent Immunoassay) technology.
- IgG antibodies indicate prior or chronic exposure to H. pylori, a bacterium that infects the stomach lining.
- The test is useful for initial screening, but does not distinguish between active and past infection.
❓ Why is the Test Done?
To:
- Detect prior or chronic H. pylori infection
- Evaluate patients with dyspepsia, gastritis, or peptic ulcers
- Screen asymptomatic individuals with a history of infection or at risk of gastric cancer
- Support diagnosis when non-invasive tests are unavailable or inconclusive
📊 Normal Range / Reference Values
Result | Interpretation |
|---|---|
Negative / Not Detected | No IgG antibodies – likely no prior infection |
Positive / Detected | Presence of IgG antibodies – suggests past or chronic infection |
Equivocal | Borderline; may need repeat test or alternative method |
⚠️ A positive result does not confirm active infection, as IgG may persist months to years after eradication.
📈 Interpretation of Results
Result | Meaning |
|---|---|
Positive IgG | Indicates prior or chronic infection – may or may not be active now |
Negative IgG | Likely no exposure, or early phase of infection before IgG is produced |
Persistent IgG | May remain detectable even after successful treatment |
🧠 Associated Organs & Conditions
Organ | Associated Conditions |
|---|---|
Stomach / Duodenum | - Chronic gastritis |
Immune System | Indicates humoral immune response to bacterial infection |
🔄 Related / Follow-Up Tests
- H. pylori Stool Antigen Test – Best for detecting active infection
- H. pylori Urea Breath Test (UBT) – Non-invasive and highly accurate
- H. pylori IgA (ELISA) – Indicates recent or mucosal immune response
- Endoscopy with Biopsy + Rapid Urease Test (RUT) – In symptomatic or complicated cases
- H. pylori IgM (if available) – Sometimes used for early/acute phase
- CBC – If ulcers may be bleeding (anemia)
✅ Fasting Required?
Test | Fasting Requirement |
|---|---|
H. pylori IgG (CLIA) | ❌ No fasting required – Blood can be drawn anytime |
📝 Summary Table
Parameter | Details |
|---|---|
What | CLIA-based test to detect IgG antibodies against Helicobacter pylori |
Why | Screen for past or chronic infection |
Positive Result | Suggests previous or ongoing infection (not necessarily active) |
Negative Result | Likely no exposure to H. pylori |
Follow-up Tests | Stool antigen, urea breath test, endoscopy |
Associated Conditions | Gastritis, peptic ulcer disease, gastric cancer |
Fasting Required | ❌ No |
How our test process works!
