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Herpes Simplex Virus (HSV I & II)-IgG

Unit Test
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Report in 24Hrs

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At Home

Details

Detects IgG antibodies specific to: HSV-1: Commonly causes oral herpes (cold sores), HSV-2: Primarily causes genital herpes

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🧪 What is HSV I & II – IgG?

The HSV I & II – IgG test is a serological blood test that detects IgG antibodies specific to:

  • HSV-1: Commonly causes oral herpes (cold sores)
  • HSV-2: Primarily causes genital herpes

The presence of IgG antibodies indicates past exposure or latent infection with the Herpes Simplex Virus.

❓ Why is the Test Done?

To:

  • Determine past or latent HSV infection
  • Differentiate between HSV-1 and HSV-2 infections
  • Screen individuals with recurrent sores or ulcers
  • Assess asymptomatic sexual partners or during pregnancy
  • Guide prenatal counseling to prevent neonatal herpes

📊 Normal Range / Reference Values

Result

Interpretation

Negative / Not Detected

No evidence of prior exposure

Positive / Detected

Past or latent HSV infection present

Equivocal

Borderline result – repeat test recommended in 2–4 weeks

Units are typically reported as an Index Value, and cutoff values may vary by lab.

📈 Interpretation of Results

Test Result

Meaning

HSV-1 IgG Positive

Previous exposure to HSV-1 (often oral)

HSV-2 IgG Positive

Previous exposure to HSV-2 (usually genital)

Both Positive

Exposure to both HSV-1 and HSV-2

Both Negative

No prior exposure; susceptible to infection

Recent infection suspicion?

Consider HSV IgM or PCR swab of active lesions

🧠 Associated Organs & Conditions

System

Conditions

Skin/Mucosa

Cold sores (HSV-1), Genital sores (HSV-2)

Central Nervous System

Encephalitis (rare, HSV-1), Meningitis (HSV-2)

Neonatal

Neonatal herpes (from mother with active HSV-2)

Eyes

Herpes keratitis (can lead to corneal scarring)

🔄 Related / Follow-Up Tests

  1. HSV IgM – Suggests recent or acute infection
  2. HSV DNA PCR (swab from lesion) – Best for active lesions
  3. Viral culture – Less sensitive but specific
  4. TORCH Panel – In pregnant women (includes HSV screening)
  5. HIV Testing – HSV-2 co-infection increases HIV acquisition risk

✅ Fasting Required?

Test

Fasting Requirement

HSV I & II IgG

❌ No fasting required – Can be done anytime

📝 Summary Table

Parameter

Details

What

Detects IgG antibodies against HSV-1 and HSV-2

Why

To determine past infection or immunity status, especially in recurrent sores or prenatal screening

Normal Range

Negative / Not Detected

Positive Result

Indicates past or latent infection (not active)

Follow-up Tests

HSV IgM, PCR swab of lesions, HIV test

Associated Conditions

Oral herpes, genital herpes, neonatal herpes, encephalitis

Fasting Required

❌ No

How our test process works!

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