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HIV - I & II

Unit Test
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Details

Detect infection with Human Immunodeficiency Virus

199300

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customers1000+ Booked this Test

The HIV I & II test is a blood test used to detect infection with Human Immunodeficiency Virus types 1 and 2:

  • HIV-1 is the most common and widespread form globally.
  • HIV-2 is less common, primarily found in West Africa but still clinically important.

Tests used may include:

  • Rapid antibody tests
  • 4th generation ELISA (detects both p24 antigen and HIV antibodies)
  • Western blot or NAT (nucleic acid testing) for confirmation

❓ Why is the Test Done?

To:

  • Diagnose HIV infection (primary or chronic)
  • Screen blood donors, pregnant women, and high-risk individuals
  • Monitor HIV exposure risk (needle injury, unprotected sex, etc.)
  • Aid in early detection, treatment initiation, and prevent transmission

📊 Normal Range / Interpretation

Result

Interpretation

Non-reactive / Negative

No evidence of HIV infection. May still be in the window period.

Reactive / Positive

Likely HIV infection – requires confirmatory testing (e.g., Western blot, NAT)

Indeterminate

Repeat test or use confirmatory methods (PCR, antigen testing)

Most accurate results after 3–4 weeks of exposure using 4th generation tests.

🧠 Associated Organs & Conditions

System

Conditions

Immune system

Destruction of CD4+ T-cells, leading to AIDS

Opportunistic infections

TB, candidiasis, toxoplasmosis, CMV, PCP, etc.

CNS

HIV-associated neurocognitive disorder

Skin

Rashes, herpes zoster, Kaposi’s sarcoma

📈 Interpretation Timeline

Time Since Exposure

Recommended Test

<10 days

Nucleic Acid Test (NAT) – RNA detection

10–20 days

p24 antigen (4th gen ELISA) becomes detectable

>3 weeks

HIV antibodies (IgM/IgG) become detectable

>3 months

Nearly all infected individuals will test positive by antibody tests

🔄 Related / Follow-Up Tests

  • HIV Viral Load (RNA PCR) – Confirms infection and monitors therapy
  • CD4 Count – Assesses immune function
  • HIV Western Blot or Immunoblot – Confirmatory test
  • Hepatitis B & C testing – Often co-screened
  • Syphilis, VDRL, HBsAg, HCV – Common in STD panels
  • HIV Drug Resistance Genotyping – For treatment planning

✅ Fasting Required?

Test

Fasting Requirement

HIV I & II Test

❌ No fasting required – Sample can be drawn any time

📝 Summary Table

Parameter

Description

What

Detects antibodies (and sometimes p24 antigen) to HIV types 1 and 2

Why

For diagnosis, screening, and treatment monitoring of HIV

Normal Range

Non-reactive / Negative

Positive Result

Indicates HIV infection – needs confirmatory testing

Follow-up Tests

HIV RNA (Viral Load), CD4 count, Western blot, STD panel

Associated Conditions

AIDS, opportunistic infections, immune suppression

Fasting Required

❌ No

How our test process works!

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