24 Hours Urinary Uric Acid
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Measures total uric acid excretion over 24 hours to evaluate risk of kidney stones or gout.
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🧪 24-Hour Urinary Uric Acid Test
Parameter | Details |
|---|---|
Fasting Required? | ✅ Yes (recommended for 8–10 hours) |
Sample Required | Entire urine collected over 24 hours in a special container |
Main Organs Involved | Kidneys, liver |
Purpose | Measures how much uric acid your body excretes into urine over 24 hours |
🔬 What Is Uric Acid?
Uric acid is a waste product formed when your body breaks down purines, substances found in many foods (organ meats, red meat, seafood) and in your own cells. Normally, uric acid dissolves in blood, is filtered by the kidneys, and exits through urine.
📈 Normal Reference Range
- Men: 250–750 mg/24 hours
- Women: 250–600 mg/24 hours
(Ranges may vary slightly by lab and diet)
📋 Why Is It Done?
Clinical Use | Purpose |
|---|---|
🔥 Gout evaluation | Determine if gout is due to overproduction or underexcretion of uric acid |
💎 Kidney stones (uric acid type) | High urinary uric acid increases risk of uric acid nephrolithiasis |
🧬 Inherited metabolic disorders | Like Lesch-Nyhan syndrome or other purine metabolism abnormalities |
💊 Monitoring drug therapy | Like allopurinol or uricosuric agents (probenecid) |
🔍 Interpreting Results
Result | Possible Interpretation |
|---|---|
🔼 High Uric Acid | Gout (overproducers), tumor lysis syndrome, high-purine diet, hemolytic disorders |
🔽 Low Uric Acid | Kidney underexcretion, chronic kidney disease, lead nephropathy, thiazide diuretics |
🧪 Related/Complementary Tests
To Be Done With or After | Why |
|---|---|
Serum Uric Acid | Compare with urinary levels (diagnostic clue) |
Urine pH | Acidic pH favors uric acid stone formation |
24h Urine Volume and Creatinine | To assess kidney excretion ability |
Renal Function Tests (RFT/KFT) | To evaluate filtration and kidney status |
Uric Acid Stone Analysis | If a stone is passed or removed |
🧾 Preparation & Collection Tips
- Begin collection in the morning by discarding the first urine of the day.
- Then collect all urine for the next 24 hours, including the first sample the next day.
- Store in a cool place or refrigerate during collection.
- Avoid purine-rich foods (red meat, anchovies, organ meats) 1–2 days before testing.
✅ Summary
Test | Purpose | Normal Range | Sample Type |
|---|---|---|---|
24-Hour Urinary Uric Acid | Evaluates uric acid excretion, gout, stones | 250–750 mg/day (Men) | 24-hour urine |
250–600 mg/day (Women) |
How our test process works!
