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Details
Measures total uric acid excretion over 24 hours to evaluate risk of kidney stones or gout.
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| Parameter | Details |
|---|---|
| Fasting Required? | Yes (recommended for 8–10 hours) |
| Sample Required | Entire urine collected over 24 hours in a special container |
| Main Organs Involved | Kidneys, liver |
| Purpose | Measures how much uric acid your body excretes into urine over 24 hours |
Uric acid is a waste product formed when your body breaks down purines, substances found in many foods (organ meats, red meat, seafood) and in your own cells. Normally, uric acid dissolves in blood, is filtered by the kidneys, and exits through urine.
| Clinical Use | Purpose |
|---|---|
| Gout evaluation | Determine if gout is due to overproduction or underexcretion of uric acid |
| Kidney stones (uric acid type) | High urinary uric acid increases risk of uric acid nephrolithiasis |
| Inherited metabolic disorders | Like Lesch-Nyhan syndrome or other purine metabolism abnormalities |
| Monitoring drug therapy | Like allopurinol or uricosuric agents (probenecid) |
| Result | Possible Interpretation |
|---|---|
| High Uric Acid | Gout (overproducers), tumor lysis syndrome, high-purine diet, hemolytic disorders |
| Low Uric Acid | Kidney underexcretion, chronic kidney disease, lead nephropathy, thiazide diuretics |
| To Be Done With or After | Why |
|---|---|
| Serum Uric Acid | Compare with urinary levels (diagnostic clue) |
| Urine pH | Acidic pH favors uric acid stone formation |
| 24h Urine Volume and Creatinine | To assess kidney excretion ability |
| Uric Acid Stone Analysis | If a stone is passed or removed |
| Renal Function Tests (RFT/KFT) | To evaluate filtration and kidney status |
| Test | Purpose | Normal Range | Sample Type |
|---|---|---|---|
| 24-Hour Urinary Uric Acid | Evaluates uric acid excretion, gout, stones | 250–750 mg/day (Men) 250–600 mg/day (Women) | 24-hour urine |
How our test process works!

