24 Hrs Urinary Proteins
Report in 24Hrs
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Specialized test evaluating kidney function and detecting proteinuria (protein loss in urine)
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🧪 24-Hour Urinary Proteins
Aspect | Details |
|---|---|
Fasting Required? | ❌ Not necessary, but avoid high-protein meals before and during collection |
Sample Required | Entire urine collected over 24 hours |
Main Organs Involved | Kidneys (especially glomeruli and tubules) |
Test Purpose | To measure the total amount of protein excreted in urine in 24 hours |
🩺 What It Detects
- Normally, very little protein is present in urine.
- High levels may indicate damage to the glomerular filter or renal tubules, leading to protein leakage.
📈 Normal Range
- <150 mg/24 hours: Normal
- 150–500 mg/24 hours: Mild proteinuria
- 500–3500 mg/24 hours: Moderate proteinuria
- >3500 mg/24 hours: Nephrotic-range proteinuria
🔬 Clinical Uses
Condition | Relevance |
|---|---|
✅ Chronic Kidney Disease (CKD) | Proteinuria is a major marker for CKD staging |
✅ Diabetic Nephropathy | Detects early kidney damage in diabetics |
✅ Hypertension-related nephropathy | Helps assess renal impact of long-standing high BP |
✅ Nephrotic Syndrome | Diagnostic hallmark is >3.5 g/day proteinuria |
✅ Glomerulonephritis | Detects inflammation and damage to glomerular structures |
✅ Lupus Nephritis | Monitors autoimmune-related kidney involvement |
📋 Interpreting Results
Proteinuria Type | Range | Possible Cause |
|---|---|---|
Normal | <150 mg/day | Healthy kidney |
Microalbuminuria | 30–300 mg/day | Early diabetic/hypertensive nephropathy |
Overt proteinuria | >300 mg/day | CKD, glomerulonephritis, lupus nephritis |
Nephrotic-range | >3500 mg/day | Nephrotic syndrome, severe glomerular damage |
🧪 Related / Follow-Up Tests
Test | Purpose |
|---|---|
Serum Creatinine, eGFR | Assess overall kidney function |
Spot Urine Protein/Creatinine Ratio (PCR) | Faster alternative, especially in outpatient settings |
Serum Albumin | Low in nephrotic syndrome |
Lipid Profile | Often elevated in nephrotic patients |
Urine Microscopy | Check for RBCs, WBCs, casts, and crystals |
ANA, dsDNA, C3/C4 | Autoimmune causes (e.g. lupus nephritis) |
🧾 Collection Instructions
- Discard the first morning urine on Day 1.
- Collect all urine for the next 24 hours, including first urine of Day 2.
- Store in a cool, dark place or refrigerate if instructed.
- Avoid high-protein meals during collection to prevent false positives.
- Label and return as instructed by the lab.
✅ Summary Table
Test | Purpose | Normal Range | Sample |
|---|---|---|---|
24-Hour Urinary Proteins | Detect and quantify protein loss in urine | <150 mg/day | 24-hour urine |
How our test process works!
