Abdomen mass biopsy -Medium 1-3 cm
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Diagnostic procedure used to evaluate a suspicious growth or lesion in the abdominal cavity
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🔬 Abdominal Mass Biopsy (Medium: 1–3 cm)
Aspect | Details |
|---|---|
Size of Lesion | Medium-sized mass: 1–3 cm diameter |
Purpose | To determine whether the mass is benign, malignant, infectious, or inflammatory |
Biopsy Type | Typically core needle biopsy (CNB) or fine-needle aspiration (FNA), guided by ultrasound or CT |
Sample Type | Tissue or cellular sample from the mass |
Anesthesia | Local anesthesia (sedation if needed) |
🧪 Why Is It Done?
Possible Diagnoses | Examples |
|---|---|
✅ Malignancy (cancer) | Lymphoma, gastrointestinal stromal tumor (GIST), colon cancer |
✅ Benign tumors | Lipoma, leiomyoma |
✅ Infections | Tuberculosis (abdominal TB), abscess |
✅ Inflammatory or granulomatous lesions | Crohn’s disease, sarcoidosis |
✅ Metastasis from another cancer | E.g., breast, ovarian, lung cancers spreading to abdomen |
📌 Common Sites of Abdominal Masses
- Liver
- Kidney
- Pancreas
- Ovary
- Lymph nodes (mesenteric or retroperitoneal)
- Bowel or colon wall
🩺 Procedure Overview
- Pre-biopsy imaging (Ultrasound/CT/MRI) to localize the mass
- Skin cleaning and local anesthesia
- A needle is inserted through the skin to collect sample(s)
- Multiple passes may be made to ensure accuracy
- Sample sent to pathology for histopathological analysis
⚠️ Risks & Complications
Risk | Details |
|---|---|
Bleeding | Especially if vascular mass is punctured |
Infection | Rare; aseptic precautions minimize this |
Organ injury | Risk depends on mass location (e.g. bowel, kidney) |
Tumor seeding (rare) | Dislodging tumor cells into biopsy track |
🧪 What Happens After?
- Histopathology Report (typically in 3–5 days) provides:
- Nature of mass: benign vs malignant
- Cell type, grade, and margins
- Markers like Ki-67, CD markers, cytokeratins, etc.
🔍 Further Tests Based on Biopsy Result
If Malignant | Recommended Workup | ||
|---|---|---|---|
PET-CT / CT Chest-Abdomen | To assess spread (staging) | ||
Tumor markers (e.g., CEA, CA-125) | For primary source or recurrence monitoring | ||
Molecular studies / IHC | Genetic mutations, therapeutic targets | ||
Surgery/Oncology referral | For further treatment plan | ||
If Infectious/Inflammatory | Recommended Workup | ||
AFB Stain / GeneXpert / TB PCR | If TB suspected | ||
ANA, ASCA, CRP | For autoimmune/inflammatory bowel disease | ||
Culture + Sensitivity | For abscess or infection | ||
✅ Summary Table
Parameter | Value |
|---|---|
Biopsy Site | Abdominal mass (1–3 cm) |
Procedure Type | Ultrasound/CT-guided needle biopsy |
Purpose | Diagnostic – cancer, infection, inflammation |
Risk | Low, generally safe with image guidance |
Turnaround Time | 3–5 working days for pathology report |
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