Allergen, Individual-Micro organism Aspergillus Fumigatus fungus
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Specific IgE Antibody Test to Aspergillus fumigatus
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🧪 Allergen, Individual – Microorganism: Aspergillus fumigatus (Fungus)
Parameter | Details |
|---|---|
Test Name | Specific IgE Antibody Test to Aspergillus fumigatus |
Sample Type | Blood (serum) |
Fasting Required? | ❌ No fasting required |
Method | Immunoassay (e.g., ELISA or ImmunoCAP) |
Result | Reported in kU/L (kilo units per liter), with reference to IgE class levels |
🧠 What Is Aspergillus fumigatus?
Aspergillus fumigatus is a common airborne fungus that can cause allergic reactions and respiratory diseases, especially in people with weakened immune systems or lung conditions.
It is one of the most clinically significant species of Aspergillus and is commonly found in:
- Soil
- Compost
- Decaying vegetation
- Indoor dust
🎯 Purpose of the Test
This test checks for specific IgE antibodies against Aspergillus fumigatus, indicating whether a person is sensitized or allergic to this fungus.
🧬 Diseases/Conditions Detected
Condition | Description |
|---|---|
Allergic Bronchopulmonary Aspergillosis (ABPA) | Common in asthma or cystic fibrosis patients |
Aspergillus-induced Asthma | IgE-mediated hypersensitivity leading to respiratory symptoms |
Hypersensitivity Pneumonitis (Mold Lung) | Chronic inflammation due to repeated exposure |
Fungal Sinusitis | Allergic reaction to fungal spores in sinuses |
Occupational Allergy | Mold allergies in farmers, compost handlers, bakers |
📊 Interpretation of IgE Levels (May Vary by Lab)
Class | IgE (kU/L) | Interpretation |
|---|---|---|
Class 0 | <0.35 | Negative / No sensitization |
Class 1 | 0.35 – 0.70 | Low sensitization |
Class 2 | 0.71 – 3.50 | Moderate sensitization |
Class 3 | 3.51 – 17.50 | High sensitization |
Class 4+ | >17.50 | Very high / Strong allergic response |
🔗 Recommended Additional Tests
Test | Why It’s Needed |
|---|---|
Total IgE | To evaluate overall allergic profile |
Lung function tests (PFTs) | If symptoms suggest asthma or ABPA |
HRCT Chest Scan | Detect bronchiectasis or ABPA lung changes |
Skin Prick Test | Optional confirmatory test for fungal allergies |
Eosinophil Count | Often elevated in allergic or parasitic conditions |
Serum Galactomannan or PCR | In suspected invasive aspergillosis in immunocompromised patients |
🌬️ Symptoms That May Prompt This Test
- Wheezing, coughing, breathlessness
- Asthma that worsens with damp environments
- Chronic sinusitis or nasal blockage
- Fatigue and respiratory distress in mold-prone settings
✅ Summary Table
Test | Aspergillus fumigatus Specific IgE |
|---|---|
Purpose | Detect fungal allergy or hypersensitivity |
Sample | Blood (serum) |
Main Conditions Detected | ABPA, fungal asthma, allergic sinusitis |
Organs Involved | Lungs, sinuses |
Next Steps If Positive | Allergen avoidance, antifungals, corticosteroids, immunotherapy |
How our test process works!
