Allergy - Non-vegetarian Panel

Allergy

Report in 48Hrs

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No Fasting Required

Details

IgE-based panel for meat, fish, poultry, eggs.

₹7,622₹10,889

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Allergy - Non-vegetarian Panel

Why is it done?
- Detects IgE antibodies against common non-vegetarian food allergens including meat, poultry, seafood, eggs, and related animal products
- Diagnoses allergic reactions to non-vegetarian food sources in individuals with suspected food allergies
- Identifies specific protein triggers causing allergic symptoms such as urticaria, angioedema, GI distress, or anaphylaxis
- Ordered when patients report symptoms after consuming non-vegetarian foods or have a history of allergic reactions
- Used to guide dietary management and reduce risk of accidental exposure to allergenic foods
- Typically performed during initial allergy evaluation or when adding new non-vegetarian foods to the diet
Normal Range
- Reference Values: < 0.35 kU/L (Class 0 - Negative/Not Detected)
- Units of Measurement: kilounits per liter (kU/L) expressed in allergen-specific IgE classes
- Interpretation of Results:
  - Negative (Class 0): < 0.35 kU/L - No detectable IgE antibodies; unlikely to have allergic reaction to tested allergen
  - Positive (Class 1-6): ≥ 0.35 kU/L - Detectable IgE antibodies indicating potential allergy
  - Borderline: 0.35-0.70 kU/L - May indicate early sensitization or minimal allergic response
- Common Non-vegetarian Panel Allergens Tested:
  - Beef, pork, lamb, chicken, turkey, fish, shellfish (shrimp, crab), eggs, and dairy products
Interpretation
- Positive Results (Class 1-6):
  - Class 1 (0.35-0.70 kU/L): Very weak reaction; allergy possible but less likely
  - Class 2 (0.70-3.50 kU/L): Weak reaction; probable allergy
  - Class 3 (3.50-17.50 kU/L): Moderate reaction; definite allergy
  - Class 4 (17.50-52.50 kU/L): Strong reaction; strong allergy
  - Class 5-6 (> 52.50 kU/L): Very strong reaction; risk of severe or anaphylactic reactions
- Negative Results (< 0.35 kU/L):
  - No specific IgE antibodies detected; low probability of IgE-mediated allergy
  - Does not exclude food intolerance, non-IgE mediated allergies, or delayed hypersensitivity reactions
- Factors Affecting Results:
  - Cross-reactivity between similar proteins (e.g., among different shellfish species or poultry types)
  - Antihistamine use within 3-7 days may suppress allergic response
  - Severe allergic reactions or anaphylaxis history may cause elevated baseline IgE
  - Age and timing of allergen exposure influence sensitization patterns
  - Concurrent infections or immune system disorders may affect IgE levels
- Clinical Significance:
  - Correlation with clinical symptoms is essential; positive results must correlate with patient history
  - Quantitative results help assess allergy severity and predict reaction risk
  - Guides dietary avoidance strategies and education on label reading
Associated Organs
- Primary Organ Systems Involved:
  - Gastrointestinal system (mouth, esophagus, stomach, intestines)
  - Immune system (circulating antibodies, mast cells, basophils)
  - Integumentary system (skin) - urticaria and dermatitis manifestations
  - Respiratory system (larynx, bronchi, lungs)
  - Cardiovascular system - systemic involvement in anaphylaxis
- Medical Conditions Associated with Abnormal Results:
  - IgE-mediated food allergies (Type I hypersensitivity reactions)
  - Atopic syndrome (increased predisposition to allergies)
  - Allergic rhinitis concurrent with food allergies
  - Asthma exacerbation triggered by food allergens
  - Eosinophilic esophagitis or gastroenteritis
  - Occupational allergies (fish or shellfish processors, butchers)
- Potential Complications from Abnormal Results:
  - Oral allergy syndrome (localized allergic reactions in mouth)
  - Acute urticaria and angioedema
  - Gastrointestinal symptoms (nausea, vomiting, diarrhea, abdominal pain)
  - Allergic asthma with bronchospasm and respiratory compromise
  - Laryngeal edema with airway obstruction
  - Anaphylaxis with hypotension, shock, and potential fatality
  - Nutritional deficiencies from unnecessary dietary restriction based on false positives
Follow-up Tests
- Additional Tests Based on Positive Results:
  - Specific allergen component testing (molecular allergology) for more precise allergen identification
  - Skin prick testing for confirmation and to assess degree of reactivity
  - Oral food challenge test (supervised by allergist) to confirm clinical allergy
  - Allergen-specific IgG testing to assess tolerance or previous exposure
  - Basophil activation test (BAT) for complex allergic cases
- Complementary Tests for Symptom Evaluation:
  - Complete blood count (CBC) to assess eosinophilia suggesting allergic response
  - Total IgE level for assessment of overall allergic burden
  - Serum tryptase level in cases of suspected anaphylaxis
  - Comprehensive metabolic panel if gastrointestinal symptoms suggest malabsorption
- Monitoring Frequency:
  - Initial assessment: Single test at diagnosis
  - Annual retesting: For monitoring children to assess natural resolution of allergies
  - After immunotherapy: Every 6-12 months to assess desensitization efficacy
  - If clinical symptoms change: Repeat testing to reassess allergen sensitivity
- Related Allergy Panel Testing:
  - Vegetarian panel (nuts, seeds, legumes, grains) for comprehensive food allergy screening
  - Inhalant allergen panel (pollen, molds, dust mites, pet dander)
  - Contact allergen testing for occupational or environmental exposures
Fasting Required?
- Fasting Status: NO - Fasting is NOT required for this test
- Pre-test Instructions:
  - Patient may eat and drink normally before the test
  - No need to restrict food intake or allergen exposure before testing
  - Arrive well-hydrated to facilitate blood draw procedure
- Medications to Avoid Before Test:
  - Critical: Antihistamines (H1 and H2 blockers) should be discontinued 3-7 days before testing
  - Corticosteroids (topical and systemic) may be continued unless specifically instructed otherwise
  - Tricyclic antidepressants should be avoided 2-3 weeks prior as they have antihistamine properties
  - Decongestants with sedating properties should be avoided for 24 hours
- Special Preparations:
  - Inform healthcare provider of all current medications, supplements, and herbal remedies
  - Discuss recent infections or immune-related conditions that may affect results
  - Avoid strenuous exercise 24 hours before blood collection
  - Maintain regular sleep schedule before appointment
  - Avoid alcohol consumption 12-24 hours before the test
  - Document recent exposure to tested allergens and timing of symptoms
  - Have list of foods consumed in past 1-2 weeks to correlate with symptoms

How our test process works!