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Allergy Panel - Food Vegetarians Panel

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No Fasting Required

Details

IgE antibody panel for common vegetarian foods (lentils, wheat, soy, nuts, vegetables).

7,84411,206

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Allergy Panel - Food Vegetarians Panel

  • Why is it done?
    • Identifies IgE antibodies to common plant-based food allergens typically consumed by vegetarians
    • Diagnoses suspected food allergies in individuals following vegetarian or vegan diets
    • Helps determine triggers for allergic reactions such as urticaria, angioedema, anaphylaxis, or gastrointestinal symptoms
    • Typically ordered when patients report symptoms after consuming plant-based foods including nuts, legumes, grains, or vegetables
    • Performed during initial allergy evaluation or when dietary modifications are needed for symptom management
    • Essential for vegetarians and vegans to safely identify safe food choices while maintaining adequate nutrition
  • Normal Range
    • Reference Values (IgE Specific Antibodies): Negative/Non-Reactive: < 0.35 kU/L (kilounits per liter)
    • Borderline/Equivocal: 0.35 - 0.69 kU/L (may warrant additional testing or clinical correlation)
    • Positive/Elevated Levels (Graded I-VI):
    • Class I: 0.70 - 3.49 kU/L (low sensitivity, mild allergy risk)
    • Class II: 3.50 - 17.49 kU/L (moderate sensitivity)
    • Class III: 17.50 - 49.99 kU/L (high sensitivity)
    • Class IV: 50.00 - 99.99 kU/L (very high sensitivity)
    • Class V: 100.00 - 149.99 kU/L (extremely high sensitivity)
    • Class VI: > 150.00 kU/L (extremely high sensitivity with strong reaction risk)
    • Interpretation:
    • Negative results indicate no detectable IgE antibodies to tested allergens
    • Positive results indicate sensitization to specific food allergens; higher values suggest stronger allergic response
    • Units measured in kU/L (kilounits per liter) using quantitative immunoassay methodology
  • Interpretation
    • Negative Results (< 0.35 kU/L):
    • No specific IgE antibodies detected to tested food allergens
    • Individual is unlikely to have IgE-mediated allergic response to these foods
    • If symptoms persist, consider non-IgE mediated food intolerances or other underlying conditions
    • Borderline Results (0.35 - 0.69 kU/L):
    • Results near the cutoff require clinical correlation with patient symptoms and history
    • Repeat testing or confirmatory testing may be warranted
    • Oral challenge testing may be considered to confirm clinical relevance
    • Positive Results (≥ 0.70 kU/L):
    • Specific IgE antibodies present; indicates sensitization to tested allergen
    • Class I-II (0.70 - 17.49 kU/L): Mild to moderate sensitization; clinical symptoms variable
    • Class III-VI (≥ 17.50 kU/L): High to extremely high sensitization; greater risk of clinical reactions
    • Avoidance of identified allergens is recommended; patient counseling essential
    • Typical Vegetarian Panel Allergens Tested:
    • Tree nuts (almonds, cashews, walnuts, pecans, Brazil nuts)
    • Legumes (peanuts, soybeans, lentils, chickpeas)
    • Seeds (sesame, sunflower, pumpkin)
    • Grains (wheat, oats)
    • Vegetables (tomato, celery, mushrooms)
    • Factors Affecting Test Results:
    • Cross-reactivity between similar foods may cause false positives
    • Antihistamine use within 3-5 days may suppress immune response and affect accuracy
    • Severity of reactions does not always correlate with test value levels
    • Recent anaphylaxis may temporarily reduce detectable IgE levels
    • IgE levels may naturally decrease over time with allergen avoidance
  • Associated Organs
    • Primary Organ Systems Involved:
    • Gastrointestinal system: mouth, esophagus, stomach, small intestine, colon
    • Integumentary system: skin mast cells triggering urticaria and pruritus
    • Respiratory system: nasal passages, pharynx, larynx, lungs, bronchi
    • Immune system: mast cells, basophils producing allergic cascade reactions
    • Cardiovascular system: potential vasodilation and shock with severe reactions
    • Associated Medical Conditions:
    • IgE-mediated food allergy
    • Oral allergy syndrome (cross-reactivity with pollen allergens)
    • Allergic rhinitis and asthma exacerbation with food allergen exposure
    • Atopic dermatitis with food allergen triggers
    • Food protein-induced gastroenterocolitis syndrome (FPIES)
    • Eosinophilic esophagitis and other eosinophilic GI disorders
    • Potential Complications with Positive Results:
    • Anaphylaxis: severe, potentially life-threatening systemic reaction
    • Angioedema: swelling of deep skin layers, particularly lips, tongue, throat
    • Bronchospasm and respiratory compromise
    • Severe GI symptoms including vomiting, diarrhea, abdominal pain
    • Nutritional deficiencies if multiple plant allergens require avoidance
    • Secondary bacterial infection of skin lesions from scratching
  • Follow-up Tests
    • Additional Tests Based on Results:
    • Comprehensive allergy panel: expanded testing for additional food allergens not included in vegetarian panel
    • Skin prick testing: confirmatory testing with direct allergen application to skin
    • Oral food challenge: controlled administration of suspected allergen under medical supervision
    • Total IgE level: assess overall allergic sensitization status
    • Component-resolved diagnostics (CRD): identify specific allergenic proteins within foods
    • Tryptase level: if anaphylaxis suspected, helps confirm mast cell activation
    • Complementary Diagnostic Tests:
    • Inhalant allergen panel: screen for pollen allergies contributing to oral allergy syndrome
    • Complete metabolic panel: establish nutritional status and baseline organ function before dietary restrictions
    • Iron and vitamin B12 studies: assess risk of deficiency with restricted plant-based diet
    • Celiac panel (tissue transglutaminase, total IgA): rule out celiac disease with wheat allergy
    • IgG food sensitivity testing: evaluate non-IgE mediated food intolerances if symptoms persist
    • Monitoring and Reassessment Frequency:
    • Initial follow-up: within 2-4 weeks to assess patient comprehension and adaptation to dietary restrictions
    • Annual or biennial reassessment: IgE levels may naturally decrease with sustained allergen avoidance
    • As-needed retesting: if new symptoms develop suggesting reaction to different allergen
    • Desensitization follow-up: if undergoing immunotherapy, baseline and periodic monitoring of IgE and IgG4
    • Related Consultation Services:
    • Allergy and Immunology specialist consultation for management plan development
    • Registered Dietitian: create nutritionally adequate meal plans with allergen avoidance
  • Fasting Required?
    • Fasting Requirement: No fasting is required for this test
    • Blood sample can be drawn at any time of day
    • Food or fluid intake does not affect IgE antibody test results
    • Medication Considerations:
    • Avoid antihistamines (H1 and H2 blockers) for 3-5 days before testing
    • Common antihistamines to discontinue: diphenhydramine, cetirizine, loratadine, ranitidine, famotidine
    • Tricyclic antidepressants may affect results; notify phlebotomist if taking these medications
    • Systemic corticosteroids may transiently reduce IgE levels; discuss with ordering physician
    • Proton pump inhibitors and other routine medications do not interfere with test
    • Pre-Test Instructions:
    • Normal meals and beverages are permitted morning of test
    • Avoid consuming tested allergens immediately before blood draw to minimize immune activation
    • Arrive for appointment well-hydrated to facilitate blood draw
    • Inform phlebotomist and laboratory of all current medications and supplements
    • Provide detailed history of allergic reactions and symptoms to healthcare provider
    • Avoid strenuous exercise or emotional stress for 24 hours before testing if possible
    • Post-Test Care:
    • Results typically available within 1-3 business days
    • Schedule follow-up appointment with allergist to discuss results and management plan
    • Apply pressure to venipuncture site for 2-3 minutes if bleeding continues
    • Report any persistent bleeding, bruising, or signs of infection at puncture site

How our test process works!

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