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ANC Profile

Pregnancy

32 parameters

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Report in 8Hrs

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At Home

nofastingrequire

No Fasting Required

Details

Measures absolute neutrophil count with differential profile.

₹1,249₹1,832

32% OFF

Parameters

  • List of Tests
    • CBC
    • Sugar (Glucose) Fasting
    • HBsAg
    • TSH
    • Urine - Complete
    • Anti HCV - Total
    • ABO Blood Group and Rh Type
    • HIV I & II
    • VDRL (RPR)

ANC Profile - Comprehensive Test Guide

  • Why is it done?
    • The ANC (Antenatal Care) Profile is a comprehensive screening package designed to assess the overall health and detect potential complications during pregnancy
    • CBC (23) screens for anemia, infections, and blood cell disorders that could affect maternal health and fetal development
    • Fasting Glucose detects gestational diabetes mellitus (GDM), a pregnancy-specific metabolic disorder affecting 2-10% of pregnancies
    • HBsAg (Hepatitis B Surface Antigen) screening prevents vertical transmission of Hepatitis B to the neonate
    • TSH (Thyroid Stimulating Hormone) assessment identifies thyroid disorders that can affect fetal neurodevelopment and pregnancy outcomes
    • Complete Urine Analysis detects urinary tract infections, proteinuria, and glycosuria which can indicate complications
    • Anti-HCV (Hepatitis C antibody) screening prevents transmission of Hepatitis C to the baby
    • ABO Blood Group and Rh Type determination ensures safe blood transfusion if needed during delivery and identifies risk of hemolytic disease in Rh-negative mothers
    • HIV I & II screening identifies maternal HIV infection to prevent mother-to-child transmission (MTCT)
    • VDRL (RPR) screening detects syphilis, a sexually transmitted infection that can cause severe fetal complications including stillbirth and congenital syphilis
    • Typically ordered during first antenatal visit (first trimester) and may be repeated in third trimester for certain tests
    • Acts as a baseline assessment for maternal health status and guides management decisions throughout pregnancy
  • Normal Range
    • CBC (Complete Blood Count - 23 parameters): Hemoglobin: 11.0-13.0 g/dL (normal for pregnancy); WBC: 4,500-11,000 cells/μL; RBC: 3.5-5.0 million/μL; Platelets: 150,000-400,000/μL; Hematocrit: 33-39%
    • Fasting Glucose: <92 mg/dL (or <5.1 mmol/L) for fasting values in pregnant women; WHO threshold for GDM diagnosis
    • HBsAg (Hepatitis B Surface Antigen): Negative - indicates no Hepatitis B infection; Positive - indicates active or chronic Hepatitis B infection
    • TSH (Thyroid Stimulating Hormone): 0.1-2.5 mIU/L (first trimester); 0.2-3.0 mIU/L (second/third trimester); normal range adjusted for pregnancy
    • Urine - Complete: Protein: Negative/Trace; Glucose: Negative; RBC: 0-3/hpf; WBC: 0-5/hpf; Bacteria: Negative; Casts: Negative
    • Anti-HCV (Hepatitis C Antibody): Negative - no Hepatitis C infection; Positive - may indicate current or past Hepatitis C infection; requires confirmation with HCV RNA test
    • ABO Blood Group: Type A, B, AB, or O (describes red cell antigens); Rh Type: Positive (presence of RhD antigen) or Negative (absence of RhD antigen)
    • HIV I & II: Negative (Undetectable/Non-reactive) - no HIV infection; Positive (Reactive/Detectable) - indicates HIV infection requiring confirmatory testing
    • VDRL (Venereal Disease Research Laboratory): Non-reactive/Negative - no syphilis; Reactive/Positive - indicates syphilis infection; reported as titer (1:1, 1:2, 1:4, etc.)
  • Interpretation
    • CBC Interpretation: Hemoglobin <11.0 g/dL indicates maternal anemia increasing miscarriage and preterm delivery risk; elevated WBC (>11,000) suggests infection; low platelets (<150,000) warrant investigation for thrombocytopenia or HELLP syndrome risk
    • Fasting Glucose >92 mg/dL meets diagnostic criteria for gestational diabetes; levels 92-125 mg/dL warrant further 75g OGTT testing; >125 mg/dL suggests overt diabetes requiring insulin management
    • HBsAg Positive: Indicates Hepatitis B infection; requires HBeAg and HBV DNA testing; neonatal vaccination and immunoglobulin (HBIG) prophylaxis needed; vertical transmission risk 10-90% depending on HBeAg status
    • TSH Elevated (>2.5 mIU/L first trimester): Indicates hypothyroidism; requires Free T4 confirmation; associated with increased miscarriage, preterm birth, and impaired fetal neurodevelopment; levothyroxine therapy recommended
    • TSH Suppressed (<0.1 mIU/L): May indicate hyperthyroidism or over-replacement; associated with atrial fibrillation and fetal tachycardia; requires Free T4 evaluation and dose adjustment
    • Urine Protein >1+ or positive proteinuria: Suggests preeclampsia, chronic kidney disease, or urinary tract infection; requires 24-hour urine protein measurement and BP monitoring
    • Urine Glucose present: Indicates glycosuria; normal in pregnancy due to increased glomerular filtration but warrants glucose screening; may indicate GDM or diabetes
    • Urine Bacteria or WBC >5/hpf: Suggests urinary tract infection (UTI) or asymptomatic bacteriuria; requires urine culture and treatment to prevent pyelonephritis and preterm labor
    • Anti-HCV Positive: Requires confirmatory HCV RNA (RT-PCR) testing; positive RNA indicates active viremia; transmission risk 3-5% during pregnancy; impacts feeding decisions
    • Rh Negative Mother: Sensitization risk if fetus is Rh positive; requires antenatal RhIG prophylaxis at 28 weeks and postnatal within 72 hours of delivery
    • Rh Positive with Negative Partner: Generally safe; monitor for ABO incompatibility risk if newborn jaundice develops
    • HIV Positive: Requires antiretroviral therapy (ART) initiation; reduces MTCT to <1% if undetectable viral load; affects delivery mode and feeding decisions
    • VDRL Reactive: Requires RPR confirmation and FTA-ABS (Fluorescent Treponemal Antibody Absorption) for confirmation; indicates active or past syphilis; warrants partner notification and treatment
    • High VDRL titer (≥1:8) in first/second trimester: Indicates active infection; treatment with benzathine penicillin G prevents congenital syphilis in 98% of cases if given before 18 weeks gestation
  • Associated Organs
    • CBC: Evaluates bone marrow (hematopoietic system), spleen (blood cell reservoir and destruction), and circulating blood; detects anemia affecting placental perfusion, leukemia, and thrombotic disorders
    • Fasting Glucose: Evaluates pancreatic beta cells and insulin production; identifies pancreatic dysfunction; detects gestational diabetes affecting placental metabolism and fetal hyperinsulinemia
    • HBsAg: Detects Hepatitis B virus infection of liver; identifies risk of liver cirrhosis, hepatocellular carcinoma, and vertical transmission
    • TSH: Evaluates thyroid gland and hypothalamic-pituitary-thyroid (HPT) axis; hypothyroidism increases miscarriage (3 times), preterm birth, and intellectual disability in offspring; hyperthyroidism causes maternal complications
    • Urine Analysis: Evaluates kidneys (glomerular filtration), urinary tract, and bladder; detects kidney disease, UTI, preeclampsia, and diabetes complications
    • Anti-HCV: Detects Hepatitis C virus infection of liver; identifies risk of chronic hepatitis, cirrhosis, hepatocellular carcinoma, and potential vertical transmission
    • ABO Blood Group and Rh Type: Evaluates red blood cells and immune system; critical for identifying hemolytic disease risk (ABO incompatibility, Rh disease), transfusion compatibility, and alloimmunization
    • HIV I & II: Detects infection of CD4+ T lymphocytes and immune system; identifies risk of opportunistic infections, AIDS, and prevention of mother-to-child transmission
    • VDRL: Detects Treponema pallidum infection affecting multiple organ systems; congenital syphilis causes fetal developmental damage, skeletal abnormalities, CNS involvement, and hepatosplenomegaly
  • Follow-up Tests
    • CBC Abnormalities: Complete Metabolic Panel (CMP) for electrolytes and renal function; Peripheral smear for cell morphology; Reticulocyte count if anemia suspected; Coagulation profile (PT/INR, aPTT) if platelet abnormalities present
    • Elevated Fasting Glucose: 75g Oral Glucose Tolerance Test (OGTT) at 24-28 weeks if initial value 88-92 mg/dL; HbA1c for assessment of glycemic control; repeated monitoring monthly if GDM diagnosed; fetal growth ultrasound at 32 weeks
    • HBsAg Positive: HBeAg and anti-HBe for infectivity assessment; HBV DNA (PCR) quantification for viral load; Anti-HBc to differentiate acute vs chronic infection; Liver function tests (ALT, AST, bilirubin); Hepatitis B vaccination for newborn within 12 hours
    • Elevated TSH: Free T4 (fT4) measurement for thyroid function assessment; Thyroid peroxidase (TPO) and thyroglobulin antibodies to identify autoimmune thyroiditis; repeat TSH every 6-8 weeks during pregnancy for dose adjustment
    • Urine Abnormalities: Urine culture and sensitivity if bacteria/pyuria present; 24-hour urine protein if proteinuria ≥1+; blood pressure monitoring; Doppler ultrasound to assess fetal well-being; serum creatinine and BUN if kidney disease suspected
    • Anti-HCV Positive: HCV RNA by RT-PCR (quantitative) to confirm active infection; Liver function tests (ALT, AST, GGT); hepatitis C genotype testing; specialist referral to hepatology or maternal-fetal medicine
    • Rh Negative Status: Indirect Coombs test (Antibody Screening) at first visit; RhIG (Rh immunoglobulin) 300 μg at 28 weeks gestation; repeat Coombs at delivery; post-partum RhIG within 72 hours if baby is Rh positive
    • HIV Positive: CD4+ count and HIV RNA viral load assessment; Opportunistic infection prophylaxis if CD4 <200 cells/mm3; antiretroviral therapy regimen adjustment; repeat viral load at 32-34 weeks to confirm undetectable status (<50 copies/mL)
    • VDRL Reactive: FTA-ABS (Fluorescent Treponemal Antibody Absorption) or TP-PA (Treponema pallidum Particle Agglutination) for confirmation; RPR titer quantification; Partner testing and notification; Penicillin G treatment initiation; repeat RPR at delivery to assess treatment response
    • Monitoring Frequency: ANC Profile tests repeated at third trimester (28-32 weeks) for HIV, HBsAg, VDRL, and Urine analysis in high-risk populations; monthly glucose monitoring if GDM diagnosed
  • Fasting Required?
    • YES - Fasting is required for this test package
    • Fasting Duration: 8-12 hours (overnight fasting preferred; typically nothing to eat or drink after midnight before morning blood draw)
    • Reason for Fasting: Fasting glucose measurement requires empty stomach to establish baseline blood sugar levels; food intake elevates glucose falsely, compromising gestational diabetes screening accuracy
    • Medications to Avoid: Continue prenatal vitamins unless otherwise advised; most routine medications can be taken with small sip of water; consult physician about diabetes or thyroid medications (usually taken on empty stomach anyway)
    • Dietary Restrictions: No food or beverages (except plain water) for 8-12 hours prior to blood draw; avoid sugary drinks, juice, coffee with cream/sugar, milk, or snacks
    • Water Intake: Drinking plain water is encouraged to maintain hydration and facilitate blood draw; dehydration can affect blood glucose levels and hemoconcentration
    • Timing: Schedule blood draw in early morning (7-9 AM) when fasting state is maintained; morning collections ensure consistent results and easier compliance with fasting requirement
    • Physical Activity: Avoid strenuous exercise for 24 hours before testing as it can affect glucose and other metabolic parameters; light activity (walking) is acceptable
    • Stress Management: Minimize stress before testing as stress hormones elevate glucose levels; relax for 10 minutes before blood draw if possible
    • Special Considerations for Pregnant Women: Schedule appointment to avoid excessive nausea if morning sickness is present; recline during blood draw to prevent syncope; bring snack to eat after collection; maintain normal sleep schedule before testing

How our test process works!

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