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Anti Chlamydia trachomatis Antibody Igg
Bacterial/ Viral
Report in 192Hrs
At Home
No Fasting Required
Details
Detects IgG antibodies against Chlamydia trachomatis.
₹962₹1,374
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Anti Chlamydia trachomatis Antibody IgG - Comprehensive Test Information Guide
- Why is it done?
- Test Purpose: Detects IgG antibodies produced by the immune system in response to Chlamydia trachomatis infection. This test identifies past or chronic chlamydial infections, as IgG antibodies indicate previous exposure to the pathogen.
- Primary Indications: Evaluation of patients with history of sexually transmitted infections; investigation of chronic pelvic pain or infertility; assessment of tubo-ovarian pathology; evaluation of reactive arthritis; screening for past chlamydial exposure in sexually active individuals; assessment of seronegative cases with clinical suspicion
- Typical Timing/Circumstances: Performed when acute infection testing (IgM) is negative but clinical suspicion remains high; during follow-up evaluation weeks to months after symptomatic infection; in evaluation of chronic inflammatory conditions related to past chlamydial exposure; as part of infertility workup; during assessment of complications such as pelvic inflammatory disease
- Normal Range
- Reference Range Values: Negative: <0.8 or <1.0 Index (varies by laboratory); Borderline/Equivocal: 0.8-1.0 or 1.0-1.1 Index; Positive: >1.0 or >1.1 Index (laboratory-specific)
- Units of Measurement: Index value or optical density (OD); some labs report as IU/mL (International Units per milliliter) or qualitative positive/negative/equivocal
- Result Interpretation: Negative = No detectable IgG antibodies; absence of past or current infection or seroconversion not yet occurred; Positive = Presence of IgG antibodies indicating past or ongoing infection; Borderline/Equivocal = Requires repeat testing or additional investigations to confirm
- Normal vs Abnormal Meaning: Normal (Negative) = No evidence of past chlamydial infection; no immune response to C. trachomatis antigens detected. Abnormal (Positive) = Evidence of past or current chlamydial infection; immune system has produced IgG antibodies in response to antigen exposure
- Interpretation
- Positive IgG Result: Indicates past exposure to C. trachomatis; may indicate current infection if combined with positive IgM; suggests previous infection even if currently asymptomatic; chronic persistent infection possible; does not indicate immunity or protection against reinfection
- Negative IgG Result: No past infection detected; acute infection possible if recently exposed (before seroconversion window); rules out chronic or recurrent infection; suggests susceptibility to primary infection
- Borderline/Equivocal Result: Inconclusive; recommend repeat testing after 1-2 weeks; may indicate early seroconversion; potential cross-reactivity with other organisms; requires clinical correlation
- Factors Affecting Results: Time since infection (seroconversion typically occurs 2-3 weeks post-infection); immunocompromised status (may have delayed or absent response); prior treatments affecting antibody levels; laboratory methodology and assay sensitivity; cross-reactivity with similar organisms; sample handling and storage conditions
- Clinical Significance Patterns: IgG positive + IgM positive = Recent acute infection; IgG positive + IgM negative = Past infection/chronic infection; IgG negative + IgM positive = Very early acute infection; IgG negative + IgM negative = No current or past infection; High IgG titers = Recent infection or chronic persistent infection
- Associated Organs
- Primary Organ Systems: Urogenital tract (urethra, bladder); reproductive organs (fallopian tubes, ovaries, endometrium, prostate, epididymis); mucosal surfaces (conjunctiva, respiratory tract); joints (reactive arthritis); rectum and anus
- Associated Medical Conditions: Pelvic inflammatory disease (PID); chronic urethritis; prostatitis; epididymitis; tubo-ovarian abscess; ectopic pregnancy; infertility; reactive arthritis (Reiter syndrome); conjunctivitis; neonatal pneumonia and conjunctivitis; chronic pelvic pain; cervicitis; urethritis
- Diseases Diagnosed or Monitored: Chlamydial infection (past or chronic); sexually transmitted infections; complications of untreated chlamydia; chronic sequelae of past infection; immunological responses to infection
- Potential Complications Associated with Abnormal Results: Tubal factor infertility; ectopic pregnancy; chronic pelvic inflammatory disease; adhesions and scarring; chronic pelvic pain syndrome; neonatal complications if untreated during pregnancy; conjunctivitis in newborns; pneumonia in infants; reactive arthritis with joint inflammation; orchitis; prostatitis complications
- Follow-up Tests
- Recommended Additional Tests: Anti Chlamydia trachomatis IgM antibody (to assess for recent/acute infection); Chlamydia trachomatis nucleic acid amplification test (NAAT) or PCR (to detect active infection); Anti Chlamydia trachomatis IgA antibody (indicates mucosal infection); Repeat IgG testing if borderline result
- Imaging Studies if Clinically Indicated: Pelvic ultrasound (to evaluate tubo-ovarian pathology, free fluid, adhesions); Hysterosalpingography (for tubal patency in infertility workup); MRI pelvis (for detailed evaluation of chronic pelvic disease)
- Additional Serological Tests: Screening for other STIs (gonorrhea, syphilis, HIV, hepatitis B and C); evaluation for reactive arthritis (ESR, CRP, HLA-B27, joint imaging)
- Monitoring Frequency: Repeat testing in 1-2 weeks if borderline result; 3-6 weeks after treatment to document clearance; annual screening for sexually active individuals at risk; repeat testing if clinical symptoms persist despite treatment
- Complementary Tests: Urinalysis and urine culture; genital culture or smear; direct fluorescent antibody (DFA) testing; enzyme immunoassay (EIA) for confirmatory testing; test of cure following treatment (typically 3-6 weeks post-therapy)
- Fasting Required?
- Fasting Requirement: No
- Fasting Duration: Not applicable - no fasting required for this serology test
- Special Instructions: No specific dietary restrictions; patient may eat and drink normally; no liquid or food restrictions prior to phlebotomy
- Medications to Avoid: No specific medications need to be withheld; continue regular medications as prescribed; recent antibiotic treatment may affect culture results but does not affect antibody serology
- Patient Preparation Requirements: Arrive well-hydrated; bring identification and insurance information; inform phlebotomist of any bleeding disorders or medications affecting coagulation; may wear comfortable clothing with accessible arm for blood draw; no special prior preparation needed for serology testing
- Sample Collection: Standard venipuncture (blood draw from arm); typically 5-7 mL serum required; collected in standard serum separator tube (SST); no special handling required; samples should be processed promptly; can be frozen if delayed testing necessary
How our test process works!
