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Anti Hepatitis A Virus (ANTI HAV) - IgM

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The Anti-HAV IgM test detects IgM antibodies produced by the immune system in response to acute Hepatitis A virus (HAV)

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🧪 Anti-HAV IgM (Anti–Hepatitis A Virus Immunoglobulin M)

Parameter

Details

Full Name

Anti-Hepatitis A Virus – IgM Antibody

Sample Type

Blood (Serum)

Fasting Required

❌ No

Method

ELISA / CLIA (Enzyme Immunoassay or Chemiluminescence)

🔬 What Is It?

The Anti-HAV IgM test detects IgM antibodies produced by the immune system in response to acute Hepatitis A virus (HAV) infection.

  • IgM is the first antibody to appear in response to HAV.
  • Indicates a recent or ongoing infection.

🧠 Organs Involved

Organ/System

Involvement

Liver

Target organ of HAV, often inflamed

Immune System

Produces IgM antibodies in acute phase

🎯 Why Is This Test Ordered?

Purpose

Clinical Context

✅ Diagnose acute hepatitis A

Patient presents with jaundice, fatigue, nausea

🧪 Identify early-stage HAV

Especially in outbreaks or contaminated food events

🛑 Confirm source of hepatitis

When ALT/AST are elevated with unknown cause

🧪 When Does IgM Appear?

  • Appears: ~2–3 weeks after exposure
  • Peaks: During symptomatic phase
  • Disappears: In 3–6 months

📊 Test Interpretation

Result

Meaning

Positive

Recent or active acute hepatitis A infection

Negative

No recent HAV infection (consider testing IgG instead)

A positive Anti-HAV IgM is diagnostic of acute HAV infection when supported by symptoms or elevated liver enzymes.

🧪 Recommended Tests to Be Done Alongside

Test

Purpose

Liver Function Tests (LFT)

Assess liver inflammation (ALT, AST, Bilirubin)

Anti-HAV IgG

Determine if patient has long-term immunity post-infection

Hepatitis B & C panel

Rule out co-infection or alternate cause of hepatitis

CBC

May show lymphocytosis or mild leukocytosis

🔬 Anti-HAV IgM vs Anti-HAV IgG

Feature

Anti-HAV IgM

Anti-HAV IgG

Appears

Early (acute phase)

Later (recovery or post-vaccination)

Duration

Short-term (disappears in months)

Long-term (lifelong immunity)

Indicates

Active/recent infection

Past infection or vaccination

✅ Summary Table

Test Name

Anti-HAV IgM

Used For

Diagnosing acute Hepatitis A

Result Meaning (Positive)

Recent or current infection

Sample Type

Serum (Blood)

Fasting Required

❌ No

Often Ordered With

Anti-HAV IgG, LFT, Hepatitis B/C markers

⚠️ Clinical Tips

  • Most cases of HAV are self-limiting, but early detection prevents transmission, especially in community or travel settings.
  • Anti-HAV IgM does not indicate immunityIgG must be tested for that.

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