Basic Arthiritis Profile - Male

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23 parameters

Report in 8Hrs

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No Fasting Required

Details

Arthritis panel tailored for males (includes uric acid, RF, CRP).

₹666₹951

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Parameters

List of Tests
- PSA - Total
- Urine Complete
- Anti - Streptolysin O
- RF
- ESR
- CRP

Basic Arthritis Profile - Male

Why is it done?
- Comprehensive screening for inflammatory and rheumatological conditions that affect joints, connective tissues, and systemic health in males
- Detection of rheumatoid arthritis (RA), autoimmune conditions, and post-streptococcal sequelae through multiple complementary markers
- PSA Total: Prostate cancer screening and assessment of prostate health in aging males
- Urine Complete: Assessment of urinary tract health, kidney function, and detection of urinary tract infections or metabolic disorders
- Anti-Streptolysin O (ASO): Detection of recent or past streptococcal infection and identification of post-streptococcal rheumatic fever risk
- Rheumatoid Factor (RF): Identification of autoimmune rheumatological diseases, particularly rheumatoid arthritis
- Erythrocyte Sedimentation Rate (ESR): Measurement of non-specific systemic inflammation and disease activity monitoring
- C-Reactive Protein (CRP): Assessment of acute phase inflammatory response and cardiovascular risk stratification
- Indicated for patients presenting with joint pain, swelling, stiffness, family history of arthritis, or systemic symptoms suggestive of inflammatory disease
- Typically recommended for men over 40 years of age or younger males with symptoms suggestive of autoimmune or inflammatory conditions
Normal Range
- PSA - Total: 0.0-4.0 ng/mL (nanograms per milliliter); normal range may vary slightly by age and laboratory methodology
- Urine Complete: Color (pale to dark yellow), Clarity (clear), pH (4.5-8.0), Specific Gravity (1.005-1.030), Protein (negative/trace), Glucose (negative), Ketones (negative), Leukocyte Esterase (negative), Nitrites (negative), RBC (0-3 per high power field), WBC (0-5 per high power field)
- Anti-Streptolysin O (ASO): Less than 200 IU/mL (International Units per milliliter) is considered negative or normal; some laboratories use 240 IU/mL as cutoff
- Rheumatoid Factor (RF): Less than 14 IU/mL (International Units per milliliter) or negative is normal; values vary by laboratory and assay method
- ESR (Erythrocyte Sedimentation Rate): 0-15 mm/hour for males; may be slightly elevated in older males (up to 20 mm/hour)
- CRP (C-Reactive Protein): Less than 3.0 mg/L (milligrams per liter) or less than 0.3 mg/dL is normal; high-sensitivity CRP may use 1.0 mg/L as upper limit
Interpretation
- PSA - Total: Values 4.0-10.0 ng/mL warrant further investigation; above 10.0 ng/mL suggests significant prostate pathology requiring digital rectal examination and possible ultrasound; rapid increase over time is concerning regardless of absolute value
- Urine Complete - Abnormal findings: Proteinuria suggests kidney disease or urinary tract pathology; glycosuria indicates diabetes or renal threshold issues; hematuria (RBC present) suggests infection, stones, or malignancy; pyuria (WBC present) indicates infection
- Anti-Streptolysin O: Values 200-400 IU/mL suggest recent or recent past streptococcal infection; values above 400 IU/mL indicate definite recent infection; rising titers on serial testing are more significant than single elevated values
- Rheumatoid Factor: Values 14-40 IU/mL are weakly positive, suggesting possible RA or other autoimmune disease; above 40 IU/mL is strongly positive and highly suggestive of RA; negative RF does not exclude RA (20% of RA patients are RF-negative)
- ESR: 15-30 mm/hour indicates mild elevation suggesting inflammation; above 30 mm/hour indicates significant inflammation or systemic disease; values above 100 mm/hour warrant investigation for serious conditions including malignancy or severe infection
- CRP: 3.0-10.0 mg/L indicates mild inflammation; above 10.0 mg/L suggests moderate to severe inflammation; extremely elevated values (>100 mg/L) warrant urgent evaluation for acute infection, trauma, or serious systemic disease
- Combination patterns: Elevated RF with elevated ESR/CRP strongly suggests active rheumatoid arthritis; elevated ASO with clinical symptoms suggests acute rheumatic fever; elevated inflammatory markers with abnormal urinalysis may indicate systemic lupus erythematosus or other connective tissue disease
- Factors affecting results: Age affects PSA levels and ESR (normally higher in elderly); recent infections increase ESR, CRP, and ASO; medications (especially NSAIDs) may affect inflammatory markers; time of day affects PSA testing; recent urinary tract trauma affects urinalysis
Associated Organs
- PSA - Total: Evaluates the prostate gland, a male reproductive organ; abnormal levels indicate benign prostatic hyperplasia (BPH), prostatitis, or prostate cancer; elevated PSA increases cardiovascular mortality risk
- Urine Complete: Evaluates kidneys, ureters, bladder, and urethra; abnormalities indicate chronic kidney disease, nephrotic syndrome, urinary tract infections, bladder disorders, or metabolic diseases affecting renal function
- Anti-Streptolysin O: Indirectly evaluates joints, heart, and connective tissues affected by post-streptococcal sequelae; evaluates immune system response to Group A Streptococcus infection
- Rheumatoid Factor: Evaluates joints, connective tissues, and synovial membrane inflammation; elevated RF indicates autoimmune attack on joint tissues; associated with rheumatoid arthritis affecting hands, feet, knees, and other joints
- ESR: Non-specific marker of whole-body inflammation; elevated in conditions affecting joints, kidneys, heart, lungs, and other organs; indicates systemic inflammatory or infectious diseases
- CRP: Acute phase reactant produced by liver in response to inflammation; elevated in cardiovascular disease, acute infections, autoimmune conditions, and malignancy; reflects whole-body inflammatory burden
- Rheumatic complications: Abnormal results collectively suggest risk for joint destruction, systemic lupus erythematosus, Sjogren's syndrome, systemic sclerosis, or vasculitis affecting multiple organ systems
Follow-up Tests
- PSA - Total elevated: PSA Free/Total ratio determination, repeat PSA in 4 weeks, transrectal ultrasound (TRUS), digital rectal examination (DRE), and possible prostate biopsy if persistently elevated
- Urine Complete abnormal: Urine culture if infection suspected, 24-hour urine protein, serum creatinine, blood urea nitrogen (BUN), ultrasound of kidneys and bladder, urology referral if hematuria present
- Anti-Streptolysin O elevated: Repeat ASO titer in 2-4 weeks to assess for rising trend, throat culture if acute infection suspected, electrocardiogram (ECG) to assess for rheumatic heart disease, echocardiogram if cardiac involvement suspected
- Rheumatoid Factor positive: Anti-CCP (anti-cyclic citrullinated peptide) antibodies, ANA (antinuclear antibody) panel, complement levels (C3, C4), complete metabolic panel, imaging of affected joints, rheumatology consultation
- ESR elevated: Differential diagnosis workup including complete blood count, comprehensive metabolic panel, comprehensive autoimmune panel, chest X-ray if infection suspected, bone marrow biopsy if markedly elevated with anemia
- CRP elevated: Repeat CRP in follow-up visits to monitor response to treatment, additional inflammatory markers (IL-6, TNF-alpha if available), imaging studies based on clinical presentation, cardiac risk assessment with lipid panel
- Pattern-based follow-up: If RF, ESR, and CRP all elevated, consider HLA-B27 testing, additional specific antibodies (anti-Ro, anti-La, anti-Sm), and imaging of affected joints; recommended monitoring frequency every 6-12 weeks for active inflammatory disease
- Long-term monitoring: Periodic repeat of this panel to assess disease progression or response to DMARDs (disease-modifying antirheumatic drugs); PSA screening should continue annually or based on physician discretion; renal function should be monitored if any urine abnormalities persist
Fasting Required?
- Overall Fasting Requirement: NOT strictly required for this test package; however, fasting for 8-12 hours is recommended for optimal accuracy and consistency
- Specific test guidance: PSA testing does not require fasting; Urine Complete is best performed on first morning void but fasting not required; Anti-Streptolysin O does not require fasting; Rheumatoid Factor does not require fasting; ESR does not require fasting; CRP does not require fasting
- Medications: Avoid NSAIDs (ibuprofen, naproxen, aspirin) for 48 hours before testing as they may artificially lower ESR and CRP values; corticosteroids should not be discontinued without physician guidance; continue regular medications unless specifically instructed otherwise
- Timing considerations: Collect urine sample as first morning void for optimal results; PSA levels fluctuate slightly throughout the day (lower in morning); collect blood samples in morning between 7:00-9:00 AM for consistency in inflammatory markers
- Additional preparation: Avoid excessive physical exertion or stress for 24 hours before testing, as vigorous exercise and psychological stress can elevate inflammatory markers; avoid alcohol for 24 hours before testing; maintain normal hydration levels
- PSA-specific considerations: Avoid ejaculation for 48 hours before PSA testing; avoid vigorous cycling for 48 hours before testing as it may elevate PSA; wait at least 4-6 weeks after prostate manipulation, cystoscopy, or biopsy before PSA testing
- Urine sample preparation: Perform genital hygiene before collection; use clean-catch midstream technique to minimize contamination; do not include the first portion of urine or the last drops; collect sample in sterile container provided by laboratory
- Acute infection timing: If acute streptococcal infection is suspected, ideally collect sample 2-3 weeks after symptom onset as ASO titers take time to develop; acute phase inflammatory markers may be highest at 3-5 days post-infection

How our test process works!