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Blood C/S - BacT/Alert (without bottle)

Bacterial/ Viral
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Report in 120Hrs

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At Home

nofastingrequire

No Fasting Required

Details

Detect bacteria or fungi in bloodstream causing sepsis or systemic infections

4201,045

60% OFF

Blood C/S - BacT/Alert (without bottle)

  • Why is it done?
    • Detects bacterial and fungal pathogens in the bloodstream to diagnose sepsis, bacteremia, and systemic infections
    • Identifies causative organisms responsible for fever of unknown origin and systemic infection
    • Performs antimicrobial susceptibility testing to guide appropriate antibiotic therapy
    • Ordered when patients present with symptoms of systemic infection: fever, chills, hypotension, tachycardia, or signs of sepsis
    • Typically performed during acute illness, upon hospital admission, or when sepsis is suspected
    • May be repeated if initial culture is negative but clinical suspicion remains high
  • Normal Range
    • Normal Result: Negative (No growth detected after 5 days of incubation)
    • Abnormal Result: Positive (Growth of bacteria or fungi detected)
    • Time to Detection: Typically 24-48 hours for common pathogens; full identification and susceptibility may take 3-5 days
    • Units: Organism identification (organism name and type), colony-forming units (CFU/mL when quantified)
    • Interpretation Guide: Negative = No bloodstream infection; Positive = Confirmed bacteremia or fungemia requiring treatment
  • Interpretation
    • Negative Culture: Indicates no bacteria or fungi detected in bloodstream; suggests infection is localized or non-infectious cause of symptoms
    • Positive Culture with Pathogenic Organism: Confirms bacteremia/fungemia; common pathogens include Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Candida species
    • Positive Culture with Skin Contaminant: May represent contamination (e.g., Coagulase-negative Staphylococcus, Corynebacterium); correlation with clinical presentation required
    • Antimicrobial Susceptibility: Reported as susceptible (S), intermediate (I), or resistant (R) to specific antibiotics; guides targeted therapy
    • Factors Affecting Results: Prior antibiotic therapy, improper collection technique, contamination during sample processing, timing of collection relative to fever spikes
    • Clinical Significance: Critical for diagnosing sepsis, endocarditis, osteomyelitis, and other serious infections; positive results warrant immediate clinical attention and initiation of targeted antimicrobial therapy
  • Associated Organs
    • Primary Systems Involved: Circulatory system (bloodstream), immune system, cardiovascular system
    • Conditions Associated with Abnormal Results: Sepsis, bacteremia, fungemia, endocarditis, osteomyelitis, meningitis, pneumonia with bacteremia, urinary tract infections with sepsis, wound infections, intra-abdominal infections
    • Diseases Diagnosed or Monitored: Infective endocarditis, catheter-related bloodstream infections, hospital-acquired infections (HAI), community-acquired infections, nosocomial infections
    • Potential Complications: Septic shock, multi-organ failure, disseminated intravascular coagulation (DIC), cardiovascular collapse, death if untreated; increased morbidity in immunocompromised patients
    • High-Risk Populations: Immunocompromised patients, those with central venous catheters, elderly patients, neonates, patients with indwelling medical devices
  • Follow-up Tests
    • If Culture Positive: Repeat blood cultures after 48-72 hours to document clearance of bacteremia; source control imaging (CT, ultrasound, echocardiography); additional cultures from suspected infection sites
    • Complementary Tests: Complete blood count (CBC), procalcitonin, lactate levels, C-reactive protein (CRP), blood glucose, liver and kidney function tests, coagulation studies
    • Imaging Studies: Transthoracic or transesophageal echocardiography for endocarditis evaluation, CT chest/abdomen/pelvis for sepsis source identification
    • Monitoring Frequency: Repeat cultures recommended if clinical deterioration occurs; follow-up cultures at end of antibiotic therapy for certain infections
    • If Culture Negative with High Clinical Suspicion: Repeat blood cultures; consider molecular/PCR-based testing; cultures from other body sites (urine, CSF, respiratory secretions); review prior antibiotic exposure
    • Related Microbiological Tests: Gram stain of blood culture broth, molecular pathogen identification, rapid identification panels, extended antimicrobial susceptibility panels
  • Fasting Required?
    • Fasting Requirement: No
    • Special Preparation Instructions: Patient may eat and drink normally; no dietary restrictions required
    • Medications: Do not discontinue antibiotics or other medications unless specifically instructed; antibiotic therapy may affect culture results if initiated before collection
    • Sample Collection Timing: Collect samples during febrile episodes or sepsis presentation when feasible; before or early in course of antibiotic therapy for optimal culture yield
    • Collection Technique: Peripheral venipuncture preferred; cleanse skin with 70% alcohol or chlorhexidine using circular motion; allow skin to air dry; use aseptic technique to prevent contamination
    • Volume Requirements: Typically 8-10 mL per culture bottle (without bottle refers to standalone collection); multiple sets from different sites recommended for better diagnostic accuracy
    • Additional Patient Preparation: Inform patient of test purpose; position patient comfortably; avoid talking or coughing during collection; transport samples to laboratory immediately at room temperature

How our test process works!

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