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Cervix biopsy - Small <1cm

Biopsy
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Report in 288Hrs

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At Home

nofastingrequire

No Fasting Required

Details

Evaluation of abnormal Pap smear, diagnosis of precancerous or cancerous lesions

₹299₹800

63% OFF

Cervix Biopsy - Small (<1cm)

  • Why is it done?
    • Diagnostic evaluation of abnormal Pap smear results (ASC-US, LSIL, HSIL, or atypical glandular cells)
    • Investigation of visible cervical lesions, polyps, or abnormal tissue growths during colposcopic examination
    • Detection and confirmation of cervical dysplasia, cervical intraepithelial neoplasia (CIN), or cervical cancer
    • Evaluation of abnormal bleeding, vaginal discharge, or persistent cervical inflammation
    • Assessment of human papillomavirus (HPV) infection and associated cervical changes
    • Follow-up of previous abnormal cytology or treated cervical lesions
  • Normal Range
    • Normal/Negative Result: No dysplasia, no malignancy, benign cervical tissue with normal squamous epithelium, normal columnar endocervical cells, or benign inflammatory changes
    • Specimen Quality: Adequate tissue sample with sufficient epithelium for accurate histopathologic evaluation
    • Benign Findings: Cervicitis, polyps, cysts, metaplasia, or other non-malignant pathology
  • Interpretation
    • Benign Findings: Normal cervical epithelium, chronic cervicitis, polyps, or squamous metaplasia; indicates absence of dysplasia or cancer
    • CIN Grade 1 (Mild Dysplasia): Abnormal cells involving lower third of epithelium; often associated with HPV infection; may regress spontaneously or progress; requires monitoring and potential treatment
    • CIN Grade 2 (Moderate Dysplasia): Abnormal cells involving up to two-thirds of epithelium; increased risk of malignant progression; typically requires treatment such as excisional procedures
    • CIN Grade 3 (Severe Dysplasia/Carcinoma in Situ): Abnormal cells involving full thickness of epithelium; significant malignant potential; requires prompt treatment and close follow-up
    • Invasive Cervical Cancer: Malignant cells breaching basement membrane into underlying stroma; requires staging, oncologic consultation, and treatment planning (surgery, radiation, chemotherapy)
    • Adenocarcinoma or Adenocarcinoma In Situ (AIS): Malignant glandular cells; associated with higher risk; typically requires hysterectomy or other aggressive management
    • Factors Affecting Results: Specimen adequacy, biopsy location, tissue orientation, patient age, HPV status, hormonal status, prior treatments, and histologist expertise
  • Associated Organs
    • Primary Organ: Cervix uteri (lower portion of uterus); part of female reproductive system
    • Related Organs: Uterus, vagina, endocervix, external cervical os, squamocolumnar junction
    • Associated Diseases:
      • Cervical intraepithelial neoplasia (CIN) grades 1-3
      • Cervical cancer (squamous cell carcinoma, adenocarcinoma)
      • Human papillomavirus (HPV) infection and related lesions
      • Cervical polyps and benign lesions
      • Chronic cervicitis and inflammatory conditions
      • Adenocarcinoma in situ (AIS)
    • Potential Complications:
      • Minimal vaginal bleeding or spotting (usually self-limited)
      • Mild cramping or pelvic discomfort
      • Rare infection (cervicitis or pelvic inflammatory disease)
      • Very rare perforation of cervix or uterine wall
      • Malignancy progression if dysplasia not identified and managed appropriately
  • Follow-up Tests
    • If Benign Results:
      • Return to routine cervical cancer screening (annual Pap smear or HPV testing per guidelines)
      • If HPV positive with benign findings, may require HPV-based surveillance
    • If CIN Grade 1 Diagnosed:
      • Repeat Pap smear in 12 months
      • HPV testing and surveillance
      • Consider ablative or excisional treatment in some cases
    • If CIN Grade 2 or 3 Diagnosed:
      • Excisional procedure (LEEP, cold knife cone biopsy, or laser cone) with negative margins
      • Follow-up Pap smear at 3 and 6 months post-treatment
      • HPV testing and extended surveillance for 20+ years
      • Colposcopy with repeat biopsy if persistently abnormal
    • If Invasive Cancer Diagnosed:
      • Urgent oncology referral
      • Staging studies (imaging, cystoscopy, rectoscopy as indicated)
      • Treatment planning (surgery, radiation, chemotherapy, or combinations)
    • Complementary Tests:
      • HPV testing (reflex HPV or co-testing)
      • Pap cytology for comparison
      • Immunohistochemistry (p16, Ki-67) for better classification in borderline cases
      • Colposcopy for additional biopsies if needed
  • Fasting Required?
    • Fasting Required: No
    • Timing and Scheduling:
      • Schedule during follicular phase of menstrual cycle (days 5-20 from menstruation onset) when cervix is most accessible
      • Avoid scheduling during menstruation or heavy bleeding
    • Medications to Avoid:
      • No specific medications need to be avoided
      • Continue regular medications including oral contraceptives
    • Patient Preparation Instructions:
      • Avoid douching 24 hours prior to procedure
      • Avoid vaginal intercourse, tampons, and spermicides 24 hours before biopsy
      • Wear comfortable, loose clothing for easy access during examination
      • Empty bladder and bowel before procedure for comfort
      • Arrange transportation as mild sedation may be offered
      • Avoid aspirin and NSAIDs 48-72 hours prior if possible (increases bleeding risk)
    • Post-Procedure Care:
      • Expect vaginal spotting or light bleeding for 1-2 weeks
      • Avoid tampons, douching, and sexual intercourse for 1-2 weeks
      • Report heavy bleeding, fever, severe pain, or foul-smelling discharge to healthcare provider

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