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Child Nutrition and Toxicity Profile

Blood

77 parameters

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Report in 12Hrs

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At Home

fastingrequire

Fasting Required

Details

A combined screening panel for children that evaluates nutritional status (vitamins, minerals, proteins) along with toxic element exposure (like lead, arsenic, mercury, cadmium, aluminium).

₹2,999₹4,171

28% OFF

Parameters

  • List of Tests
    • Calcium
    • Uric Acid
    • 25 OH Vitamin D
    • TSH
    • Folic Acid
    • Vitamin B12
    • BUN, Creatinine, BUN/Creatinine
    • Lipid Profile
      • Cholesterol/HDL
      • LDL/HDL
      • Non-HDL
      • VLDL
      • Total Cholesterol
      • Triglycerides
      • HDL
      • LDL
    • Iron Studies
      • Iron
      • TIBC
      • Transferrin
    • Liver Function Test
      • Albumin
      • Alkaline Phosphatase
      • Bilirubin - Direct
      • Bilirubin - Indirect
      • Bilirubin - Total
      • SGOT
      • SGPT
      • Total Protein
      • A/G
      • GGT
      • Globulin
    • G6PD
    • Hemoglobinopathies Profile
      • Bands - F
      • Bands - A
      • Bands - S
      • Bands - C
      • Bands - E
      • Bands - A2
      • Bands - D
      • Bands - Unknown
    • Blood Toxic Element Profile
      • Arsenic
      • Cadmium
      • Chromium
      • Cobalt
      • Lead
      • Mercury
      • Selenium
      • Barium
      • Caesium
    • CBC - Complete Hemogram

Child Nutrition and Toxicity Profile

  • Why is it done?
    • Comprehensive assessment of pediatric nutritional status and metabolic health in children
    • Detection of toxic element exposure and bioaccumulation in growing children who are particularly vulnerable
    • Evaluation of micronutrient deficiencies that can impair growth, development, and cognitive function
    • Screening for metabolic disorders, hemoglobinopathies, and G6PD deficiency prevalent in pediatric populations
    • Assessment of thyroid function and bone health in developing children
    • Monitoring lipid metabolism and cardiovascular risk factors in pediatric patients
    • Evaluation of children with poor growth, developmental delays, pallor, or exposure to contaminated environments
    • Baseline assessment during well-child visits and as part of comprehensive health screening programs
    • Investigation of non-specific symptoms including fatigue, weakness, irritability, or delayed milestones
    • Monitoring children in resource-limited settings with high malnutrition prevalence
  • Normal Range
    • Calcium: 8.5-10.5 mg/dL (2.1-2.6 mmol/L) - essential for bone development and muscle function in children
    • Uric Acid: 3.5-7.2 mg/dL (0.21-0.43 mmol/L) for children; normal range varies with age
    • 25-OH Vitamin D: 30-100 ng/mL (75-250 nmol/L) - optimal for bone health and immune function
    • TSH (Thyroid Stimulating Hormone): 0.5-5.0 mIU/L for children - critical for growth and metabolism
    • Folic Acid: 2.7-17.0 ng/mL (6-38 nmol/L) - essential for cell division and DNA synthesis
    • Vitamin B12: 200-900 pg/mL (148-664 pmol/L) - required for neurological development and hematopoiesis
    • BUN (Blood Urea Nitrogen): 7-20 mg/dL (2.5-7.1 mmol/L) for children
    • Creatinine: 0.3-0.7 mg/dL (26-62 µmol/L) for children; varies with age and muscle mass
    • BUN/Creatinine Ratio: 10:1 to 20:1 - indicator of kidney function and hydration status
    • Total Cholesterol: <170 mg/dL (<4.4 mmol/L) for children
    • HDL (High-Density Lipoprotein): >45 mg/dL (>1.2 mmol/L) for children - protective cholesterol
    • LDL (Low-Density Lipoprotein): <110 mg/dL (<2.8 mmol/L) for children - harmful cholesterol
    • VLDL (Very Low-Density Lipoprotein): <30 mg/dL (<0.78 mmol/L)
    • Triglycerides: <150 mg/dL (<1.7 mmol/L) for children
    • Cholesterol/HDL Ratio: <3.5 - lower ratio indicates better cardiovascular health
    • LDL/HDL Ratio: <2.0 - indicates favorable lipid profile
    • Non-HDL Cholesterol: <130 mg/dL (<3.4 mmol/L) for children
    • Iron: 50-120 µg/dL (9-21 µmol/L) for children - essential for oxygen transport
    • TIBC (Total Iron-Binding Capacity): 250-425 µg/dL (45-76 µmol/L)
    • Transferrin: 200-360 mg/dL (2.0-3.6 g/L) - iron transport protein
    • Transferrin Saturation: 20-50% - percentage of transferrin bound to iron
    • Albumin: 3.5-5.5 g/dL (35-55 g/L) - marker of protein nutrition
    • Total Protein: 6.0-8.3 g/dL (60-83 g/L)
    • Globulin: 2.0-3.5 g/dL (20-35 g/L)
    • A/G Ratio (Albumin/Globulin): 1.0-2.5 - indicates protein balance
    • Bilirubin - Total: 0.1-1.2 mg/dL (2-21 µmol/L)
    • Bilirubin - Direct: 0.0-0.3 mg/dL (0-5 µmol/L)
    • Bilirubin - Indirect: 0.1-0.9 mg/dL (2-15 µmol/L)
    • SGOT (AST - Aspartate Aminotransferase): 10-40 U/L (0.17-0.67 µkat/L)
    • SGPT (ALT - Alanine Aminotransferase): 7-56 U/L (0.12-0.93 µkat/L)
    • Alkaline Phosphatase: 30-120 U/L (0.5-2.0 µkat/L) for children; higher in growing children
    • GGT (Gamma-Glutamyl Transferase): 9-48 U/L (0.15-0.8 µkat/L)
    • G6PD (Glucose-6-Phosphate Dehydrogenase): >4.11 U/g Hb (>0.26 U/mmol Hb) - normal activity; negative screening
    • Hemoglobin F (Fetal): <1% in children beyond 6 months of age
    • Hemoglobin A: 96-98% - predominant form in normal children
    • Hemoglobin S, C, E, D: Absent in normal hemoglobin pattern
    • Hemoglobin A2: 2-3.5% - normal secondary hemoglobin
    • Lead (Pb): <5 µg/dL (<0.24 µmol/L) - acceptable level; >10 µg/dL requires intervention
    • Mercury (Hg): <5 µg/L (<25 nmol/L) - normal baseline level
    • Arsenic (As): <5 µg/L (<67 nmol/L) - normal exposure level
    • Cadmium (Cd): <0.5 µg/L (<4.5 nmol/L) - extremely low in children
    • Chromium (Cr): <2 µg/L (<38 nmol/L)
    • Cobalt (Co): <1 µg/L (<17 nmol/L)
    • Selenium (Se): 70-150 µg/L (0.89-1.90 µmol/L) - essential trace element
    • Barium (Ba): <5 µg/L (<36 nmol/L)
    • Caesium (Cs): <2 µg/L - minimal normal levels
    • Hemoglobin (Hb): 11.5-15.5 g/dL (115-155 g/L) for children 6-12 years; higher in adolescents
    • Hematocrit (Hct): 34-40% (0.34-0.40 L/L) for children 6-12 years
    • RBC (Red Blood Cell Count): 4.5-5.5 million cells/µL (4.5-5.5 × 10¹²/L)
    • MCV (Mean Corpuscular Volume): 75-95 fL - indicates size of red blood cells
    • MCH (Mean Corpuscular Hemoglobin): 24-33 pg - hemoglobin per red blood cell
    • MCHC (Mean Corpuscular Hemoglobin Concentration): 31-37 g/dL - hemoglobin concentration in RBCs
    • RDW (Red Cell Distribution Width): 11-15% - measures RBC size variation
    • WBC (White Blood Cell Count): 5.0-15.0 thousand cells/µL (5.0-15.0 × 10⁹/L) for children
    • Platelet Count: 150-400 thousand/µL (150-400 × 10⁹/L)
    • Neutrophils: 45-75% of WBC (2.5-7.5 × 10⁹/L absolute)
    • Lymphocytes: 20-50% of WBC (1.0-7.0 × 10⁹/L absolute)
    • Monocytes: 2-8% of WBC (0.2-0.8 × 10⁹/L absolute)
    • Eosinophils: 1-4% of WBC (0.1-0.4 × 10⁹/L absolute)
    • Basophils: 0-1% of WBC (0.0-0.1 × 10⁹/L absolute)
  • Interpretation
    • Calcium Abnormalities: Elevated levels (>10.5 mg/dL) may indicate hypercalcemia from vitamin D toxicity or hyperparathyroidism; low levels (<8.5 mg/dL) suggest hypocalcemia from vitamin D deficiency, hypoalbuminemia, or malabsorption, causing tetany or seizures
    • Uric Acid Abnormalities: Elevated levels may indicate gout, leukemia, or metabolic disorders; low levels can suggest xanthine oxidase deficiency or allopurinol therapy
    • Vitamin D Deficiency: <20 ng/mL indicates deficiency causing rickets, impaired bone mineralization, increased fracture risk, and immune dysfunction; 20-29 ng/mL is insufficient; >30 ng/mL is optimal
    • TSH Abnormalities: Elevated TSH (>5.0 mIU/L) indicates primary hypothyroidism affecting growth and development; low TSH (<0.5 mIU/L) suggests hyperthyroidism causing hyperactivity and accelerated metabolism; critical in early childhood screening
    • Folic Acid Deficiency: <2.7 ng/mL indicates deficiency causing megaloblastic anemia, neural tube defects, and developmental impairment; common in malabsorptive disorders and dietary insufficiency
    • Vitamin B12 Abnormalities: <200 pg/mL indicates deficiency causing macrocytic anemia, neurological deterioration, and cognitive decline; elevated levels rarely occur but may indicate myeloproliferative disorders or liver disease
    • BUN/Creatinine Interpretation: Elevated BUN (>20 mg/dL) with normal creatinine may indicate dehydration or high protein intake; elevated creatinine (>0.7 mg/dL) suggests kidney dysfunction; abnormal ratios indicate acute vs. chronic kidney disease
    • Lipid Profile Interpretation: Total cholesterol >170 mg/dL, LDL >110 mg/dL, or triglycerides >150 mg/dL indicate elevated cardiovascular risk; low HDL (<45 mg/dL) is protective factor loss; elevated ratios suggest atherosclerosis risk
    • Iron Studies Abnormalities: Low iron (<50 µg/dL) with high TIBC indicates iron deficiency anemia; elevated ferritin and iron saturation suggest hemochromatosis or chronic transfusions; transferrin saturation >45% indicates iron overload
    • Liver Function Abnormalities: Low albumin (<3.5 g/dL) indicates malnutrition or chronic liver disease; elevated bilirubin suggests jaundice or hemolysis; elevated transaminases (SGOT/SGPT) indicate hepatocyte injury; elevated ALP is expected in growing children; elevated GGT suggests cholestasis
    • G6PD Deficiency: <4.11 U/g Hb indicates deficiency increasing hemolytic crisis risk with oxidative triggers (fava beans, sulfonamides, antimalarials); X-linked inheritance with variable expression; more common in populations of African, Mediterranean, and Asian descent
    • Hemoglobinopathies Pattern Interpretation: Presence of Hb S indicates sickle cell disease or trait; Hb C suggests hemoglobin C disease; Hb E indicates E thalassemia; elevated Hb A2 (>3.5%) indicates beta-thalassemia trait; elevated Hb F suggests hemolytic disease or beta-thalassemia major
    • Lead Toxicity: 5-10 µg/dL requires monitoring and source identification; 10-44 µg/dL necessitates clinical evaluation and possible chelation consideration; >45 µg/dL indicates severe poisoning causing irreversible neurological damage, developmental delays, and learning disabilities
    • Mercury Toxicity: Elevated levels cause neurotoxicity, tremors, behavioral changes; organic mercury (methylmercury) poses highest risk; accumulates in brain and kidney; critical concern from contaminated fish and environmental exposure
    • Arsenic Toxicity: Elevated levels cause gastrointestinal symptoms, skin changes, and increased cancer risk; chronic exposure impairs cognitive development; sources include contaminated groundwater and certain pesticides
    • Cadmium Toxicity: Highly toxic even at low levels; causes renal dysfunction, bone disease, and developmental impairment; bioaccumulates with no safe threshold; sources include contaminated shellfish and industrial pollution
    • Chromium/Cobalt/Barium Toxicity: Elevated levels may indicate environmental or occupational exposure; chromium VI is particularly carcinogenic; cobalt causes allergic reactions and bone marrow suppression; barium causes GI and muscle effects
    • Selenium Status: <70 µg/L indicates deficiency causing Keshan disease and impaired antioxidant defense; >150 µg/L may cause toxicity with hair and nail changes; balance essential for thyroid and immune function
    • CBC Abnormalities: Low Hb (<11.5 g/dL) indicates anemia; elevated MCV (>95 fL) suggests macrocytic anemia from B12/folate deficiency; low MCV (<75 fL) indicates microcytic anemia from iron deficiency; elevated WBC (>15.0 × 10⁹/L) may indicate infection or leukemia; low platelets (<150 × 10⁹/L) increase bleeding risk
    • Differential Count Interpretation: Elevated neutrophils indicate bacterial infection; elevated lymphocytes suggest viral infection; elevated eosinophils may indicate parasitic infection or allergy; elevated monocytes occur in chronic infections; immature bands indicate acute infection or leukemia
  • Associated Organs
    • Calcium and Vitamin D Tests: Evaluate skeletal system, parathyroid gland function, and bone mineralization; abnormalities lead to rickets, osteomalacia, osteoporosis, tetany, and growth retardation
    • TSH and Thyroid Function: Assess thyroid gland; abnormalities affect metabolism, growth, neurological development, and temperature regulation; primary cause of preventable intellectual disability when untreated in infancy
    • Folic Acid and Vitamin B12: Evaluate bone marrow function and nervous system; deficiencies cause megaloblastic anemia, neuropathy, and developmental disorders; particularly important for rapidly dividing cells in growing children
    • BUN and Creatinine Tests: Assess kidney function and glomerular filtration rate; abnormalities indicate acute kidney injury, chronic kidney disease, dehydration, or urinary tract obstruction
    • Lipid Profile Tests: Evaluate cardiovascular system and metabolic health; abnormalities increase risk of atherosclerosis, coronary artery disease, and metabolic syndrome even in pediatric years
    • Iron Studies: Assess bone marrow, intestinal absorption, and storage organs; deficiency causes microcytic anemia and developmental delay; overload causes cirrhosis, heart disease, and endocrine dysfunction
    • Liver Function Tests: Evaluate hepatic function, protein synthesis, bile metabolism; abnormalities indicate hepatitis, cirrhosis, fatty liver disease, biliary obstruction, or toxic injury
    • G6PD and Hemoglobinopathies: Assess bone marrow and red blood cell function; abnormalities cause hemolytic anemia, tissue damage from sickling, and end-organ complications
    • Blood Toxic Elements: Assess multiple organ systems including nervous system (neurotoxicity), kidneys (nephrotoxicity), liver (hepatotoxicity), and hematopoietic system; lead accumulates in bone; mercury concentrates in brain and kidney
    • CBC Parameters: Assess bone marrow production, immune function, and oxygen-carrying capacity; abnormalities indicate anemia, infection, immune disorders, leukemia, or blood coagulation disorders
  • Follow-up Tests
    • For Calcium/Vitamin D Abnormalities: Parathyroid hormone (PTH), ionized calcium, phosphate, alkaline phosphatase, bone-specific alkaline phosphatase, magnesium; X-ray or DEXA for bone density assessment; may require genetic testing for familial hypercalcemia
    • For TSH Abnormalities: Free T4, free T3, TPO antibodies, thyroglobulin antibodies; thyroid ultrasound if structural abnormality suspected; repeat TSH screening at 1-2 week intervals if abnormal in neonatal period
    • For Vitamin B12/Folate Deficiency: Methylmalonic acid, homocysteine, intrinsic factor antibodies, parietal cell antibodies; bone marrow biopsy if megaloblastic changes evident; endoscopy to evaluate malabsorption; genetic testing for metabolic disorders
    • For Kidney Function Abnormalities: Estimated glomerular filtration rate (eGFR), urinalysis with microscopy, urine electrolytes, renal ultrasound, abdominal imaging; monitor progression at 3-6 month intervals for chronic disease
    • For Lipid Abnormalities: Apolipoprotein B, Lipoprotein(a), fibrinogen, homocysteine, C-reactive protein; ultrasound for fatty liver; genetic testing for familial hypercholesterolemia; repeat testing at 3-6 months
    • For Iron Studies Abnormalities: Ferritin, soluble transferrin receptor, reticulocyte count, peripheral blood smear; stool occult blood if deficiency; iron supplementation trial; endoscopy to investigate chronic bleeding; genetic testing for hemochromatosis
    • For Liver Function Abnormalities: Prothrombin time (PT), activated partial thromboplastin time (aPTT), INR, ammonia level, viral hepatitis serologies, autoimmune hepatitis markers, abdominal ultrasound or CT imaging; liver biopsy if cirrhosis suspected
    • For G6PD Deficiency: Confirm with enzyme assay, reticulocyte count during hemolytic episode, haptoglobin, LDH, bilirubin levels; genetic sequencing for variant identification; family screening recommended
    • For Hemoglobinopathies: High-performance liquid chromatography (HPLC), peripheral smear, reticulocyte count, splenic ultrasound, bone imaging for infarcts; genetic counseling and family testing; prenatal diagnosis for subsequent pregnancies
    • For Heavy Metal/Toxic Element Exposure: Source investigation and environmental assessment, baseline neuropsychological testing for lead, repeat testing after chelation therapy, urine heavy metal levels, home lead paint testing, water quality analysis
    • For CBC Abnormalities: Peripheral blood smear for cellular morphology, bone marrow aspirate and biopsy if malignancy suspected, flow cytometry for immune disorders, coagulation studies if platelet abnormality, imaging for splenomegaly
  • Fasting Required?
    • Fasting Status: YES - 8-12 hours fasting is required for accurate lipid profile results and some metabolic parameters
    • Fasting Duration: 8-12 hours (typically overnight fast from 8-10 PM until morning blood draw between 6-8 AM)
    • Water Intake: Plain water is permitted and encouraged during fasting period to maintain hydration
    • Medications: Continue routine morning medications with water unless specifically instructed otherwise by physician; inform laboratory staff of all medications including iron supplements, vitamins, and thyroid medications
    • Dietary Restrictions: No food, milk, juice, coffee, tea, or other beverages during fasting period; all dietary intake must cease at midnight or 8-10 hours before blood draw
    • Special Preparations: Avoid strenuous exercise 24 hours before testing; maintain normal activity level; avoid stress if possible as it can affect results
    • Child-Specific Considerations: For young children <6 years, fasting may be shortened to 6-8 hours with physician approval; schedule tests early morning for easier compliance; explain importance to child in age-appropriate manner
    • Timing of Draw: Morning collection between 6-8 AM preferred for consistent results; afternoon draws may show different values for some parameters
    • Post-Test Nutrition: After blood collection, resume normal eating and drinking immediately; bring light snack for child to prevent hypoglycemia symptoms; ensure adequate hydration following draw

How our test process works!

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