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Corn biopsy - Medium 1-3 cm

Biopsy
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Report in 288Hrs

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At Home

nofastingrequire

No Fasting Required

Details

Skin biopsy.

₹370₹529

30% OFF

Corn Biopsy - Medium 1-3 cm

  • Why is it done?
    • Histopathological examination of skin lesions on the feet to differentiate between benign corns and other dermatological conditions such as warts, calluses, or malignant lesions
    • To confirm diagnosis of heloma (corn) and rule out other pathological conditions including plantar warts, squamous cell carcinoma, or other malignant growths
    • When clinical examination is inconclusive or when lesions fail to respond to conservative treatment
    • To assess for secondary infections or inflammatory complications
    • Performed when lesions are 1-3 cm in diameter, representing medium-sized pathological specimens requiring tissue analysis
  • Normal Range
    • Normal/Benign Findings: Characteristic hyperkeratotic core with concentric arrangement of keratin layers, intact basement membrane, and absence of malignant cells
    • Interpretation Categories:
    • Benign Corn (Heloma Durum): Positive confirmation with normal histology
    • Normal Skin: Absence of pathological changes, normal epidermal-dermal architecture
    • Units of Measurement: Histological findings reported descriptively with specific architectural features noted
    • Size Reference: Medium biopsy specimens of 1-3 cm diameter provide adequate tissue for comprehensive histopathological assessment
  • Interpretation
    • Benign Corn (Heloma Durum): Shows dense keratin core with concentric lamellation, surrounding inflammatory infiltrate minimal, basement membrane intact, no atypia present
    • Plantar Wart (Verruca Vulgaris): Demonstrates thickened epidermis with columnar parakeratosis, rete ridges elongated with cupping, viral changes with koilocytes may be present
    • Callus (Tyloma): Shows diffuse hyperkeratosis and acanthosis without central keratinous core, normal skin architecture with mild inflammatory changes
    • Squamous Cell Carcinoma: Demonstrates atypical keratinocytes, increased mitotic figures, abnormal nuclear features, invasion into dermis, loss of normal architecture
    • Inflammatory Changes: May indicate secondary infection, immunological response, or irritation from chronic pressure
    • Factors Affecting Results: Proper tissue fixation, specimen orientation, adequate sampling, recent treatment history, immunological status of patient
  • Associated Organs
    • Primary System: Integumentary system (skin and soft tissues of the foot)
    • Musculoskeletal System: Involvement of underlying bony structures, pressure-related joint complications
    • Associated Conditions with Abnormal Results:
    • Heloma durum (hard corn) - most common benign finding with typical concentric keratin layers
    • Plantar warts caused by human papillomavirus (HPV) infection with potential for malignant transformation
    • Cutaneous malignancies including squamous cell carcinoma and melanoma
    • Secondary bacterial infections leading to cellulitis or abscess formation
    • Inflammatory dermatological conditions and autoimmune manifestations
    • Potential Complications:
    • Pain and functional impairment affecting gait and mobility if malignancy detected
    • Risk of metastatic disease if malignant lesion is identified
    • Post-biopsy bleeding, infection, or scarring at biopsy site
  • Follow-up Tests
    • If Benign Corn Confirmed:
    • Clinical follow-up examination in 2-4 weeks to assess healing and treatment response
    • Podiatric assessment for biomechanical correction and pressure-relieving interventions
    • If Plantar Wart Identified:
    • HPV typing may be considered for high-risk strains
    • Dermatological referral for cryotherapy, laser therapy, or immunological treatment
    • Follow-up examination at 3-6 month intervals to monitor for recurrence
    • If Malignancy Suspected or Confirmed:
    • Urgent oncology consultation and staging workup (imaging, additional biopsies if indicated)
    • CT or MRI imaging for assessment of local extension and metastatic disease
    • Sentinel lymph node biopsy if melanoma or high-grade carcinoma identified
    • Surgical excision with wide margins as primary treatment modality
    • If Secondary Infection Present:
    • Bacterial culture and sensitivity testing if not already performed
    • Antibiotic therapy based on culture results
    • Follow-up assessment in 1-2 weeks to confirm infection resolution
    • Complementary Tests:
    • Immunohistochemical staining for tumor markers and classification if malignancy detected
    • Dermoscopy for non-invasive evaluation of pigmented lesions
  • Fasting Required?
    • Fasting Required: No
    • Pre-procedure Preparation:
    • No fasting or dietary restrictions required
    • Cleanse the biopsy site thoroughly with antiseptic solution 24 hours prior if possible
    • Remove any topical medications or ointments from the lesion area 48 hours before biopsy
    • Wear comfortable, loose-fitting footwear on day of procedure
    • Medications to Avoid:
    • Discontinue aspirin and NSAIDs for 5-7 days prior if possible to reduce bleeding risk (consult with physician if on these for medical reasons)
    • Avoid anticoagulant medications if not medically contraindicated
    • Continue regular essential medications unless specifically directed otherwise by provider
    • Additional Patient Instructions:
    • Inform provider of any allergies (especially to local anesthetics) prior to procedure
    • Discuss all current medications with healthcare provider, particularly anticoagulants or immunosuppressants
    • Plan for transportation as there may be temporary discomfort affecting normal walking
    • Post-procedure wound care instructions will be provided for proper healing and infection prevention

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