Covid 19 Antibodies - Total
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This test detects total antibodies developed in response to SARS-CoV-2, the virus responsible for COVID-19.
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🧪 COVID-19 Antibodies – Total (IgG + IgM + IgA)
Test Name | COVID-19 Antibodies – Total |
|---|---|
Sample Type | Serum (blood sample) |
Fasting Required | ❌ Not required |
Detection Method | CLIA / ELISA / CMIA (depending on lab) |
Turnaround Time | 1–2 working days |
Department | Infectious Disease / Immunology |
🦠 What Does It Measure?
This test detects total antibodies developed in response to SARS-CoV-2, the virus responsible for COVID-19. It includes:
- IgM – Appears early in infection (~5–7 days)
- IgG – Appears later (~10–14 days) and lasts longer
- IgA – Found in mucosal secretions; some tests include it
🧭 When is this test recommended?
Use Case | Purpose |
|---|---|
Post-exposure or post-symptom period | Detect if individual had a past infection |
After vaccination | Assess antibody response to vaccine |
Long COVID evaluation | Check immune response post-recovery |
Pre-surgery or travel screening | Check for seropositivity (especially for history) |
Serosurveillance studies | Population-level exposure assessment |
🧬 Not for Diagnosis of Active Infection
- It cannot detect active COVID-19 infection.
- Use RT-PCR or Rapid Antigen Test if symptomatic or recently exposed.
📈 Interpretation of Results
Result | Meaning |
|---|---|
Reactive / Positive | Antibodies present → Past infection OR vaccination |
Non-reactive / Negative | No detectable antibodies → No past exposure or insufficient immune response |
🧪 Commonly Ordered With
Related Test | Purpose |
|---|---|
COVID-19 RT-PCR (Swab) | Detect active infection |
COVID-19 IgG only | Specific for long-term immunity tracking |
Neutralizing Antibody Test | Detect if antibodies can block virus from infecting cells |
COVID-19 Spike Protein Ab | Check for vaccine response |
CBC + CRP + D-Dimer + IL-6 | Monitor post-COVID or cytokine storm in moderate/severe cases |
📌 Limitations
- Antibody levels wane over time — a negative test doesn’t rule out previous infection.
- Some people, especially the elderly or immunocompromised, may not mount a strong antibody response.
💉 Vaccination & Antibody Test
- After COVID vaccination (Covishield, Covaxin, mRNA vaccines), antibodies may take 2–4 weeks to develop.
- Antibody presence doesn’t always correlate with protective immunity.
📋 Summary
Aspect | Details |
|---|---|
Use | Confirm past exposure or immune response |
Includes | IgG, IgM, ± IgA |
Result | Reactive = Exposed/Vaccinated, Non-reactive = No antibodies |
Not for | Detecting current infection |
Commonly Paired Tests | RT-PCR, Spike Ab, Neutralizing Ab |
How our test process works!
