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Covid Package

Bacterial/ Viral

64 parameters

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Report in 24Hrs

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At Home

fastingrequire

Fasting Required

Details

Comprehensive Covid profile check - SARS check, sugar, inflamation, iron, liver, lipid, kidney, thyroid, blood, diabetes, vitamins

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Parameters

  • List of Tests
    • Sugar (Glucose) Fasting
    • ESR
    • Iron Studies
      • Iron
      • TIBC
      • Transferrin Saturation
    • Liver Function Test
      • Albumin
      • Alkaline Phosphatase
      • Bilirubin - Direct
      • Bilirubin - Indirect
      • Bilirubin - Total
      • AST/SGOT
      • ALT/SGPT
      • Total Protein
      • A/G Ratio
      • Gamma GT
      • Globulin
    • Kidney Profile
      • BUN
      • Calcium
      • Creatinine
      • Uric Acid
      • eGFR
      • BUN/Creatinine
      • Urea
    • Lipid Profile
      • Cholestrol/HDL
      • LDL/HDL
      • Non HDL
      • VLDL
      • Total Cholestrol
      • Triglycerides
      • HDL
      • LDL
    • Thyroid Profile
      • Total T3
      • Total T4
      • TSH
    • Hba1c
    • eAG
    • CBC - Complete Hemogram
    • Vitamin Profile
      • 25 - OH Vitamin D
      • Folic Acid
      • Vitamin B12
    • SARS-COV-2 Spike protein IgG Antibodies

COVID Package - Comprehensive Diagnostic Guide

  • Why is it done?
    • Comprehensive assessment of COVID-19 infection status through detection of SARS-CoV-2 Spike protein IgG antibodies, indicating past infection or vaccination response
    • Evaluation of systemic health impact of COVID-19 infection through metabolic and inflammatory markers including glucose control, kidney function, liver function, and lipid metabolism
    • Assessment of nutritional status and micronutrient deficiencies (Vitamin D, B12, Folic Acid) commonly associated with COVID-19 severity and recovery
    • Evaluation of complete blood count to detect COVID-19 related hematologic abnormalities including lymphopenia, anemia, and thrombocytopenia
    • Assessment of thyroid function as COVID-19 can impact thyroid hormone metabolism and immune regulation
    • Evaluation of inflammatory markers (ESR) to assess systemic inflammation severity in COVID-19 patients
    • Monitoring for long-COVID complications including metabolic dysfunction, organ damage, and nutritional deficiencies during recovery
    • Post-vaccination antibody response verification to assess immune protection level following COVID-19 vaccination
    • Identification of pre-existing comorbidities (diabetes, cardiovascular disease) that increase COVID-19 risk severity
  • Normal Range
    • Sugar (Glucose) Fasting: 70-100 mg/dL (3.9-5.6 mmol/L) - Normal fasting blood glucose, indicating proper glucose homeostasis and pancreatic function
    • ESR (Erythrocyte Sedimentation Rate): 0-15 mm/hr in males, 0-20 mm/hr in females - Normal range indicating minimal systemic inflammation
    • Iron Studies - Iron: 60-170 μg/dL (11-30 μmol/L) - Normal serum iron level; TIBC: 250-425 μg/dL (45-72 μmol/L) - Normal total iron-binding capacity; Transferrin Saturation: 20-50% - Normal iron transport efficiency
    • Liver Function Tests: Albumin 3.5-5.0 g/dL; Alkaline Phosphatase 30-120 IU/L; Bilirubin (Total) 0.1-1.2 mg/dL, (Direct) 0.0-0.3 mg/dL, (Indirect) 0.1-1.0 mg/dL; AST 10-40 IU/L; ALT 7-56 IU/L; Total Protein 6.0-8.0 g/dL; A/G Ratio 1.0-2.5; Gamma GT 9-48 IU/L (males), 9-32 IU/L (females); Globulin 2.3-3.5 g/dL
    • Kidney Profile: BUN 7-20 mg/dL (2.5-7.1 mmol/L); Calcium 8.5-10.5 mg/dL (2.12-2.62 mmol/L); Creatinine 0.7-1.3 mg/dL (62-115 μmol/L); Uric Acid 3.5-7.2 mg/dL (208-428 μmol/L); eGFR >60 mL/min/1.73m²; BUN/Creatinine Ratio 10-20; Urea 2.5-7.1 mmol/L
    • Lipid Profile: Total Cholesterol <200 mg/dL (<5.18 mmol/L) - Desirable; HDL >40 mg/dL (>1.04 mmol/L) in males, >50 mg/dL (>1.30 mmol/L) in females - Protective; LDL <100 mg/dL (<2.59 mmol/L) - Optimal; Triglycerides <150 mg/dL (<1.69 mmol/L) - Normal; VLDL <30 mg/dL (<0.78 mmol/L); Non-HDL <130 mg/dL; Cholesterol/HDL Ratio <5; LDL/HDL Ratio <3
    • Thyroid Profile: TSH 0.4-4.0 mIU/L - Normal thyroid-stimulating hormone; Total T3 80-200 ng/dL (1.2-3.1 nmol/L) - Normal triiodothyronine; Total T4 4.5-12.0 μg/dL (58-154 nmol/L) - Normal thyroxine
    • HbA1c: <5.7% (<39 mmol/mol) - Normal glucose control; eAG <100 mg/dL (<5.6 mmol/L) equivalent average glucose
    • Complete Blood Count: WBC 4.5-11.0 x10³/μL; RBC 4.5-5.9 x10⁶/μL (males), 4.1-5.1 x10⁶/μL (females); Hemoglobin 13.5-17.5 g/dL (males), 12.0-15.5 g/dL (females); Hematocrit 41-53% (males), 36-46% (females); MCV 80-100 fL; MCH 27-33 pg; MCHC 32-36 g/dL; Platelets 150-400 x10³/μL
    • Vitamin Profile: 25-OH Vitamin D 30-100 ng/mL (75-250 nmol/L) - Sufficient; Vitamin B12 200-900 pg/mL (148-664 pmol/L) - Normal; Folic Acid 5.4-16.0 ng/mL (>13.5 nmol/L) - Normal
    • SARS-CoV-2 Spike Protein IgG Antibodies: Negative or <0.8 Index - Negative (no detectable antibodies); Positive or ≥0.8 Index - Positive (indicates past infection or vaccination response)
  • Interpretation
    • Sugar (Glucose) Fasting - Elevated (>126 mg/dL): Indicates impaired glucose tolerance or diabetes mellitus; Decreased (<70 mg/dL): Indicates hypoglycemia which can cause acute symptoms; Values 100-126 mg/dL suggest prediabetes and increased COVID-19 severity risk
    • ESR - Elevated (>20 mm/hr in females, >15 mm/hr in males): Indicates acute or chronic inflammation commonly seen in active COVID-19 infection, systemic inflammation, or complications; Markedly elevated values (>50 mm/hr) suggest severe inflammation or secondary infections
    • Iron - Elevated: May indicate iron overload or hemochromatosis; Decreased: Indicates iron deficiency anemia affecting oxygen transport; TIBC Elevated: Suggests iron deficiency; TIBC Decreased: Suggests iron overload; Transferrin Saturation <20%: Iron deficiency; >50%: Iron overload risk
    • Liver Function Tests - Elevated Bilirubin: May indicate hepatic impairment or hemolysis, reported in severe COVID-19; Elevated AST/ALT: Indicates hepatocellular damage, common in COVID-19 patients; Elevated Alkaline Phosphatase: Suggests cholestasis or bone involvement; Low Albumin: Indicates malnutrition or liver dysfunction associated with severe infection; Elevated Gamma GT: Indicates liver or bile duct involvement; Abnormal A/G Ratio: Reflects hepatic synthetic function impairment
    • Kidney Profile - Elevated Creatinine (>1.3 mg/dL): Indicates impaired renal function or acute kidney injury documented in severe COVID-19; Elevated BUN: Suggests renal dysfunction or dehydration; Low eGFR (<60): Indicates chronic kidney disease stage 3 or worse; Elevated Uric Acid: Risk for gout; Abnormal Calcium: May indicate bone metabolism disruption or secondary hyperparathyroidism
    • Lipid Profile - Elevated Total Cholesterol/LDL: Increases cardiovascular risk and may be abnormal during acute illness; Elevated Triglycerides (>150 mg/dL): Associated with inflammatory states and metabolic dysfunction in COVID-19; Low HDL (<40 mg/dL males, <50 mg/dL females): Reduced protective effect against atherosclerosis; Elevated VLDL: Indicates increased triglyceride burden; Elevated Cholesterol/HDL Ratio: Indicates increased cardiovascular risk
    • Thyroid Profile - Elevated TSH (>4.0 mIU/L): Indicates primary hypothyroidism; Low TSH (<0.4 mIU/L): Indicates hyperthyroidism or pituitary dysfunction; TSH abnormalities documented post-COVID-19; Low T3/T4: Indicates central hypothyroidism or sick euthyroid syndrome common in acute illness
    • HbA1c - 5.7-6.4% (39-47 mmol/mol): Prediabetic range indicating increased risk; ≥6.5% (≥48 mmol/mol): Diagnostic of diabetes mellitus; Elevated HbA1c increases COVID-19 severity risk and complications; eAG correlates with average 3-month glucose control
    • Complete Blood Count - Low WBC (<4.5): Indicates immunosuppression or bone marrow suppression; High WBC (>11.0): Indicates infection or inflammatory response; Lymphopenia (<20% differential): Characteristic finding in severe COVID-19; Elevated WBC with left shift: Suggests bacterial superinfection risk; Low Hemoglobin: Anemia affecting oxygen delivery; Low Platelets (<150): Thrombocytopenia associated with severe COVID-19 and increased bleeding risk
    • Vitamin Profile - Low Vitamin D (<30 ng/mL): Associated with increased COVID-19 severity and poor immune response; Low B12 (<200 pg/mL): May cause neurologic symptoms and immune dysfunction; Low Folic Acid (<5.4 ng/mL): Associated with anemia and immune impairment; Deficiencies impact recovery and immune competence
    • SARS-CoV-2 Spike Protein IgG Antibodies - Positive (≥0.8 Index): Indicates immune response to COVID-19 from past infection or vaccination; Negative (<0.8 Index): Indicates no detectable antibodies, suggesting no prior infection or vaccination response, or early infection before seroconversion; Antibody level correlates with immune protection level; Serial testing shows antibody persistence and durability
  • Associated Organs
    • Sugar (Glucose) Fasting - Associated Organs: Pancreas (insulin production), liver (glucose metabolism), muscles (glucose utilization); Conditions: Diabetes mellitus, metabolic syndrome, obesity-related metabolic dysfunction; COVID-19 implications: Hyperglycemia worsens infection severity and healing; Comorbid diabetes increases mortality risk 10-fold
    • ESR - Associated Organs: Vascular system (affected by inflammation), tissues throughout body; Conditions: Chronic inflammation, infection, malignancy, autoimmune diseases; COVID-19 implications: Elevated ESR correlates with systemic inflammation severity, cytokine storm markers, and poor prognosis; Useful for monitoring disease progression
    • Iron Studies - Associated Organs: Bone marrow (RBC production), liver (iron storage), intestines (iron absorption); Conditions: Iron deficiency anemia, hemochromatosis, chronic disease anemia; COVID-19 implications: Iron deficiency reduces hemoglobin causing hypoxia; Elevated iron may impair immune response; Dysregulated hepcidin in infection alters iron metabolism
    • Liver Function Tests - Associated Organs: Liver (primary target), hepatic vessels, bile ducts, gallbladder; Conditions: Hepatitis, cirrhosis, fatty liver disease, liver injury, cholestasis; COVID-19 implications: Direct hepatic injury from viral infection reported in 30-40% of cases; Elevated transaminases indicate hepatocellular necrosis; Impaired synthetic function predicts worse outcomes; Liver failure risk in severe disease
    • Kidney Profile - Associated Organs: Kidneys (filtration), nephrons (functional units), glomeruli; Conditions: Acute kidney injury, chronic kidney disease, diabetes-related nephropathy, hypertensive nephropathy; COVID-19 implications: Acute kidney injury occurs in 9-23% of hospitalized patients; Direct renal infection via ACE2 receptors on podocytes; Elevated creatinine indicates poor prognosis; Kidney failure increases mortality significantly
    • Lipid Profile - Associated Organs: Liver (lipid synthesis), blood vessels (atherosclerosis site), heart (cardiac disease risk); Conditions: Hyperlipidemia, atherosclerosis, cardiovascular disease, metabolic syndrome; COVID-19 implications: Dyslipidemia associated with severe COVID-19; Low HDL indicates inflammatory state; Elevated triglycerides with inflammation increases thrombotic risk; Post-COVID persistent lipid abnormalities may indicate long-term vascular damage
    • Thyroid Profile - Associated Organs: Thyroid gland, pituitary gland (TSH production), hypothalamus; Conditions: Hypothyroidism, hyperthyroidism, thyroiditis, Grave's disease, Hashimoto's thyroiditis; COVID-19 implications: COVID-19 associated thyroiditis reported; Thyroid hormone affects immune response and inflammation control; Abnormal thyroid function worsens COVID-19 outcomes and recovery; Post-viral thyroid dysfunction is recognized complication
    • HbA1c/eAG - Associated Organs: Pancreas (insulin production), blood (glucose measurement), tissues (glucose utilization); Conditions: Diabetes mellitus type 1 and 2, prediabetes, metabolic dysfunction; COVID-19 implications: Elevated HbA1c indicates poor glycemic control and increased infection severity; Hyperglycemia impairs immune function and increases mortality; Diabetic patients have 2-3 fold increased hospitalization rate
    • Complete Blood Count - Associated Organs: Bone marrow (cell production), spleen (blood cell sequestration/immune), lymphoid tissues (WBC origin); Conditions: Anemia, leukopenia, thrombocytopenia, leukemia, infections, autoimmune diseases; COVID-19 implications: Lymphopenia is key COVID-19 finding correlating with severity; WBC elevation indicates infection/inflammation; Anemia impairs oxygen delivery to tissues; Thrombocytopenia increases hemorrhage risk and correlates with hypercoagulability and poor outcomes
    • Vitamin Profile - Associated Organs: Bone (Vitamin D metabolism), bone marrow (B12 dependent hematopoiesis), nerves (B12 dependent myelination); Conditions: Vitamin D deficiency related rickets/osteomalacia, B12 deficiency anemia, folate deficiency anemia, neurologic complications; COVID-19 implications: Severe Vitamin D deficiency increases COVID-19 susceptibility and severity; B12 deficiency impairs immune response and recovery; Deficiencies predispose to secondary infections and poor outcomes
    • SARS-CoV-2 Spike Protein IgG Antibodies - Associated Organs: Lymphoid tissues (antibody production), lungs (primary infection site), mucous membranes (entry site), blood (antibody circulation); Conditions: COVID-19 infection, post-vaccination status, immunosuppression preventing seroconversion; COVID-19 implications: Antibodies provide immune memory and protection against reinfection; Positive results confirm prior infection or successful vaccination; Absence in vaccinated individuals may indicate immunocompromise requiring investigation
  • Follow-up Tests
    • Sugar (Glucose) Fasting - Follow-up: Oral Glucose Tolerance Test (OGTT) if 100-125 mg/dL for diabetes screening; Repeat fasting glucose in 1-2 weeks if abnormal; Continuous glucose monitoring if diabetic; Hemoglobin A1c already included in package but can be repeated in 3 months if abnormal
    • ESR - Follow-up: C-Reactive Protein (CRP) for more specific acute phase response measurement; Procalcitonin if bacterial infection suspected; Repeat ESR in 1-2 weeks to track inflammation resolution; Fibrinogen level if persistent elevation
    • Iron Studies - Follow-up: Ferritin level for iron storage assessment; Peripheral blood smear to evaluate RBC morphology; Bone marrow biopsy if severe anemia; Reticulocyte count to assess bone marrow response; Iron supplementation trial if deficient; Repeat iron studies in 4-8 weeks after supplementation
    • Liver Function Tests - Follow-up: Hepatitis B and C serology if elevated transaminases; Abdominal ultrasound for fatty liver or cirrhosis assessment; Viral hepatitis panel; Autoimmune hepatitis antibodies if autoimmune suspected; Repeat LFTs weekly during acute illness; CT abdomen if abdominal pain present; Prothrombin time/INR if synthetic dysfunction evident
    • Kidney Profile - Follow-up: 24-hour urine collection for creatinine clearance validation; Urine routine and microscopy for proteinuria/hematuria assessment; Renal ultrasound or CT if acute kidney injury; Cystatin C as alternative GFR estimate; Repeat kidney function tests daily during acute illness; Urinalysis to detect kidney damage; Consider nephrology consultation if creatinine elevated
    • Lipid Profile - Follow-up: Repeat lipid panel in 4-6 weeks; Lipoprotein(a) testing for cardiovascular risk stratification; Advanced lipid panel with particle size analysis; Apolipoprotein B measurement; Post-COVID cardiovascular assessment including ECG and stress testing; Repeat testing 3-6 months after acute illness to identify persistent abnormalities
    • Thyroid Profile - Follow-up: Free T3 and Free T4 if abnormal total levels; Thyroid antibodies (TPO, thyroglobulin) if thyroiditis suspected; Repeat thyroid panel in 4-6 weeks to confirm persistent abnormalities; Thyroid ultrasound if nodule suspected; TSH receptor antibodies if Graves' disease suspected; Repeat testing 3-6 months post-COVID to assess recovery
    • HbA1c/eAG - Follow-up: Repeat HbA1c in 3 months for diagnosis confirmation; Continuous glucose monitoring initiation; Endocrinology consultation if diabetic; Fasting and post-prandial glucose monitoring; Urine microalbumin for diabetes complications screening; Annual retinal screening for diabetic retinopathy
    • Complete Blood Count - Follow-up: Peripheral blood smear to evaluate WBC types and RBC morphology; Reticulocyte count if anemia present; Bone marrow biopsy if severe cytopenias; Flow cytometry if lymphoproliferative disorder suspected; Blood cultures if fever and elevated WBC; Repeat CBC daily during acute illness; Coagulation studies (PT/INR, aPTT, D-dimer) if thrombotic complications suspected
    • Vitamin Profile - Follow-up: Repeat vitamin levels in 4-6 weeks after supplementation; Methylmalonic acid and homocysteine if B12 deficiency suspected for neurologic assessment; 1,25-OH Vitamin D and PTH if suspected vitamin D related bone disease; Intrinsic factor antibodies if pernicious anemia suspected; Dietary assessment with nutritionist; Repeat testing 3 months after supplementation to verify repletion
    • SARS-CoV-2 Spike Protein IgG Antibodies - Follow-up: SARS-CoV-2 RT-PCR if current infection symptoms present (confirms active infection); Repeat IgG serology in 2-4 weeks to assess antibody persistence; Total antibody testing if IgG negative; Neutralizing antibody testing for vaccine effectiveness assessment; Testing at 6 and 12 months post-infection/vaccination to monitor antibody duration; IgM antibodies if recent acute infection suspected; Viral variant-specific antibody testing if reinfection suspected
  • Fasting Required?
    • YES - Fasting is REQUIRED for the complete COVID Package
    • Fasting Duration: Minimum 8-12 hours of fasting required before blood collection; Overnight fasting (12 hours) preferred for optimal accuracy; Blood collection should ideally occur between 7:00 AM - 9:00 AM after overnight fasting
    • Dietary Restrictions: No food consumption during fasting period; Water intake is allowed and encouraged; Avoid all beverages except water (no coffee, tea, juice, energy drinks, alcohol); No chewing gum or mints during fasting period
    • Medications: Continue regular morning medications unless specifically instructed otherwise by physician; Certain medications may be withheld if they interfere with testing - consult ordering physician; Antidiabetic medications should be held if instructed by physician for glucose testing; Blood pressure medications can generally be continued
    • Preparation Day Before: Avoid heavy meals 24 hours before test; Avoid excess fat, sugar, and alcohol 24 hours before test; Maintain normal physical activity; Ensure adequate sleep (7-8 hours) the night before
    • Morning of Test: Take no food after midnight; Brush teeth (spit out, do not swallow water); Avoid smoking if possible as nicotine affects results; Avoid strenuous exercise 24 hours prior; Rest for 5-10 minutes before blood collection; Sit upright during blood draw to reduce vasovagal reactions
    • Special Considerations: Women should ideally test during days 7-11 of menstrual cycle when hormone fluctuations are minimal (for lipid accuracy); Inform phlebotomist of any COVID-19 symptoms or recent infection status; Wear mask if currently symptomatic; Inform lab of all current medications including supplements; Postpone testing if experiencing acute illness; Hydration status affects results - ensure well-hydrated
    • Why Fasting Required: Fasting glucose test requires 8-12 hour food abstinence to establish baseline glucose without food influence; Lipid profile accuracy requires fasting state as postprandial triglycerides significantly elevate non-fasting; Liver and kidney profiles can be affected by food intake and require fasting for standardized interpretation; Iron studies and vitamin levels may vary with food intake; Most tests in comprehensive packages standardize results by requiring fasting state
    • Non-Fasting Tests: SARS-CoV-2 Spike Protein IgG Antibodies can be drawn non-fasting as they are unaffected by food; CBC can technically be performed non-fasting but often done with fasting package for convenience; However, for consistency and accuracy of the entire package, fasting is mandatory
    • Rescheduling: If unable to fast, reschedule appointment rather than testing non-fasting; Results obtained non-fasting will require physician interpretation caveat; If accidentally ate before test, inform lab immediately - may choose to reschedule for accurate results

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