DHEA-Sulphate (DHEAS)
Report in 24Hrs
At Home
Details
Preferred marker in blood tests for assessing adrenal androgen function
₹399₹1045
62% OFF
1000+ Booked this Test
🧪 DHEA-Sulfate (DHEAS) Test
🧬 What is DHEA-Sulfate?
Dehydroepiandrosterone sulfate (DHEA-S or DHEAS) is a steroid hormone produced primarily by the adrenal glands, with smaller amounts made by the ovaries (in women) and testes (in men). It serves as a precursor to male and female sex hormones like testosterone and estrogens.
DHEAS is more stable and has a longer half-life than free DHEA, making it the preferred marker in blood tests for assessing adrenal androgen function.
🩺 Why is the DHEAS Test Done?
The test is used to:
- Evaluate adrenal gland function
- Investigate early puberty (precocious puberty) in children
- Diagnose adrenal tumors or adrenal hyperplasia
- Help assess polycystic ovary syndrome (PCOS) in women
- Investigate excess hair growth (hirsutism) and acne
- Evaluate androgen-producing tumors (e.g., in the adrenal cortex or gonads)
📊 Normal Ranges (Typical)
(Can vary slightly by lab and age/sex)
Group | DHEAS Range (µg/dL) |
|---|---|
Men (20–50 yrs) | 180 – 560 |
Women (20–50 yrs) | 65 – 380 |
Children | Varies with age and puberty stage |
🧪 Test Overview
Parameter | Details |
|---|---|
Sample Type | Blood (serum) |
Test Method | Chemiluminescence (CLIA) / Immunoassay |
Fasting Required | ❌ Not typically required |
Collection Time | Morning sample preferred |
Turnaround Time | 1–2 days |
🔍 Interpretation of Results
Result | Possible Causes |
|---|---|
High DHEAS | - Adrenal hyperplasia |
Low DHEAS | - Adrenal insufficiency (Addison’s disease) |
🧩 Associated Organs and Conditions
Organ | Primary Role | ||
|---|---|---|---|
Adrenal Glands | Produce DHEAS and other corticosteroids | ||
Ovaries/Testes | Secondary source (minor) | ||
Pituitary Gland | Indirect control via ACTH | ||
Condition | DHEAS Role | ||
Polycystic Ovary Syndrome (PCOS) | Often elevated | ||
Adrenal Tumors | Very high levels may be present | ||
Congenital Adrenal Hyperplasia | Elevated in some forms | ||
Adrenal Insufficiency | Decreased DHEAS | ||
🔗 Related/Follow-up Tests
Test | Purpose |
|---|---|
Testosterone (Total/Free) | Assess androgen levels more directly |
LH & FSH | Evaluate pituitary-gonadal axis |
17-Hydroxyprogesterone | Screen for congenital adrenal hyperplasia |
Cortisol, ACTH | Evaluate adrenal or pituitary insufficiency |
Pelvic/Adrenal Imaging | If tumor or hyperplasia is suspected |
Prolactin, Estradiol | For broader evaluation in PCOS or menstrual irregularities |
🧾 Summary
Category | Details |
|---|---|
Test Name | DHEA-Sulfate (DHEAS) |
Sample | Serum (blood) |
Fasting | Not required |
Primary Use | Evaluate adrenal androgen production |
Organ Focus | Adrenal glands |
Commonly Used In | PCOS, adrenal disorders, puberty issues |
Follow-ups | Testosterone, Cortisol, LH/FSH, ACTH |
How our test process works!
