Search for
Eosinophils-Absolute Count
Bacterial/ Viral
Report in 4Hrs
At Home
No Fasting Required
Details
Eosinophils Absolute Count measures the actual number of eosinophils (a type of white blood cell) in a microliter (μL) of blood
₹99₹200
51% OFF
Eosinophils-Absolute Count: Comprehensive Medical Test Guide
- Why is it done?
- Measures the absolute number of eosinophil white blood cells in the bloodstream, providing quantitative data about immune system response
- Diagnoses allergic reactions, parasitic infections, and autoimmune or hematologic disorders
- Investigates persistent cough, asthma, chronic diarrhea, or skin rashes of unknown etiology
- Monitors treatment response in patients with eosinophilia-associated conditions
- Typically performed as part of a complete blood count (CBC) with differential or when specific clinical signs suggest immune activation
- Normal Range
- Reference Range: 30-350 cells/microL (0.03-0.35 × 10⁹/L) for adults
- Pediatric Range: May vary with age; typically lower in infants (0-150 cells/microL) and gradually increase to adult levels
- Units of Measurement: Cells/microL (μL) or × 10⁹/L (SI units)
- Normal Result: Indicates adequate immune response without excessive eosinophil production; suggests absence of active allergic, parasitic, or hematologic disease
- Elevated (>350 cells/microL): Eosinophilia; requires clinical correlation to determine underlying cause
- Decreased (<30 cells/microL): Eosinopenia; may indicate bone marrow suppression, acute infection, or certain medications
- Interpretation
- Mild Eosinophilia (350-1,500 cells/microL): Common with allergies, mild parasitic infections, or early-stage immune disorders; often requires clinical symptoms for diagnosis
- Moderate Eosinophilia (1,500-5,000 cells/microL): Suggests significant allergic disease, parasitic infection, or systemic conditions; warrants further investigation
- Severe Eosinophilia (>5,000 cells/microL): Indicates serious pathology such as leukemia, lymphoma, severe parasitic disease, or hypereosinophilic syndrome; requires comprehensive workup
- Factors Affecting Results: Corticosteroids (decrease eosinophils), time of day variation, stress, medications (some antibiotics), recent vaccinations, and circadian rhythm changes
- Clinical Significance: Results must be interpreted with clinical context; eosinophil counts may fluctuate with time of day and require correlation with symptoms, exposure history, and other laboratory findings
- Associated Organs
- Primary Organ Systems: Hematopoietic system (bone marrow), lymphoid tissue, lungs, gastrointestinal tract, and skin
- Allergic Disorders: Asthma, allergic rhinitis, atopic dermatitis, food allergies, drug reactions, and eosinophilic esophagitis
- Parasitic Infections: Hookworm, roundworm, tapeworm, schistosomiasis, and filariasis; parasitic infections typically produce moderate-to-severe eosinophilia
- Hematologic Malignancies: Chronic myeloid leukemia, acute myeloid leukemia, lymphoma, and hypereosinophilic syndrome; severe elevations warrant urgent investigation
- Autoimmune Conditions: Rheumatoid arthritis, systemic lupus erythematosus, polyarteritis nodosa, and granulomatosis with polyangiitis
- Potential Complications: Severe eosinophilia can cause tissue damage, thrombosis, cardiac complications, and organ dysfunction; chronic parasitic infections may lead to malnutrition and anemia
- Follow-up Tests
- Immunological Testing: Allergen-specific IgE testing, total IgE levels, and allergy skin testing to identify allergic triggers
- Parasitic Screening: Stool examination for ova and parasites, serological testing for specific parasites, and imaging studies as clinically indicated
- Hematologic Evaluation: Peripheral blood smear, bone marrow biopsy, and cytogenetic testing for suspected malignancy or severe eosinophilia
- Imaging Studies: Chest X-ray for pulmonary manifestations, abdominal ultrasound or CT for organomegaly, and other imaging based on clinical presentation
- Tissue Biopsy: Endoscopic biopsy (for eosinophilic gastrointestinal disorders) or skin biopsy when indicated
- Monitoring Frequency: Repeat eosinophil counts every 3-6 months for chronic conditions, monthly during active treatment, and as needed based on clinical response
- Related Tests: Complete blood count, white blood cell differential, comprehensive metabolic panel, liver and kidney function tests, and thyroid function tests
- Fasting Required?
- Fasting Required: No
- Special Instructions: No special fasting requirements; test can be performed at any time of day, though morning collection is preferred for consistency
- Medication Considerations: Inform provider of corticosteroid use, as these suppress eosinophil counts; other medications generally do not require discontinuation unless specifically instructed
- Patient Preparation: Ensure adequate rest and minimal stress before testing; avoid strenuous exercise on the day of collection; wear comfortable, loose clothing to facilitate venipuncture
- Timing Considerations: Eosinophil counts demonstrate circadian variation (higher at night); schedule testing consistently at same time for comparable results; wait at least 4 weeks after parasitic treatment before retesting
How our test process works!
