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Female Hormone Package

Hormone/ Element

9 parameters

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Report in 24Hrs

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At Home

nofastingrequire

No Fasting Required

Details

Hormone Profile Check for Females

₹2,999₹4,499

33% OFF

Parameters

  • List of Tests
    • FSH, LH, Prolactin
    • Estradiol
    • Thyroid Profile (Total T3, Total T4, TSH)
    • Anti Mullerian Hormone (AMH)
    • Unconjugated Estriol (E3)

Female Hormone Package

  • Why is it done?
    • Comprehensive assessment of female reproductive hormones and thyroid function to evaluate fertility, menstrual irregularities, and hormonal imbalances
    • FSH, LH, and Prolactin: Evaluate pituitary-ovarian axis function, assess ovulation patterns, identify hypogonadism or hyperprolactinemia, and diagnose polycystic ovary syndrome (PCOS) and other reproductive disorders
    • Estradiol: Measures ovarian function, assesses estrogen production levels, and evaluates menstrual cycle phase and reproductive health status
    • Thyroid Profile (Total T3, Total T4, TSH): Screen for thyroid dysfunction that can affect fertility, menstrual regularity, and hormonal balance; essential as thyroid disorders frequently impact reproductive health
    • Anti-Mullerian Hormone (AMH): Assesses ovarian reserve and egg quality, predicts fertility potential, and evaluates menopausal status or premature ovarian aging
    • Unconjugated Estriol (E3): Primarily used in prenatal screening for fetal chromosomal abnormalities (Down syndrome, Edward syndrome) and placental function assessment
    • Primary indications: Infertility evaluation, unexplained amenorrhea or oligomenorrhea, anovulation assessment, irregular menstrual cycles, suspected endocrine disorders, fertility planning, and prenatal screening
    • Synergistic testing: These tests work together to provide a complete hormonal profile, allowing clinicians to identify the specific cause of reproductive dysfunction and guide targeted treatment decisions
  • Normal Range
    • Follicle-Stimulating Hormone (FSH): Follicular phase 3.5-12.5 mIU/mL; Luteal phase 1.7-7.7 mIU/mL; Postmenopausal >25 mIU/mL; Normal indicates normal ovarian function and regular cycling
    • Luteinizing Hormone (LH): Follicular phase 2.4-12.6 mIU/mL; Ovulatory surge 24.8-294.4 mIU/mL; Luteal phase 1.7-8.6 mIU/mL; Normal range confirms ovulatory cycle presence
    • Prolactin: 4.5-29 ng/mL (or 4.5-29 μIU/mL depending on assay); Normal level indicates no interference with fertility or menstrual function
    • Estradiol: Follicular phase 24-138 pg/mL (88-506 pmol/L); Ovulatory surge 126-628 pg/mL (463-2305 pmol/L); Luteal phase 27-246 pg/mL (99-902 pmol/L); Postmenopausal <20 pg/mL; Normal indicates adequate ovarian estrogen production
    • Total T3 (Triiodothyronine): 80-200 ng/dL (1.2-3.0 nmol/L); Normal indicates adequate thyroid hormone production
    • Total T4 (Thyroxine): 4.5-11 μg/dL (58-142 nmol/L); Normal range confirms proper thyroid function
    • TSH (Thyroid-Stimulating Hormone): 0.4-4.0 mIU/L; Normal range indicates appropriate pituitary-thyroid axis function
    • Anti-Müllerian Hormone (AMH): 0.7-11 ng/mL (5-79 pmol/L); Higher values indicate better ovarian reserve; levels decrease with age and low ovarian reserve
    • Unconjugated Estriol (E3) - Second trimester: 0.7-3.5 ng/mL; Normal values consistent with appropriate fetal development and placental function; Levels vary significantly by gestational age
  • Interpretation
    • FSH Interpretation: Elevated FSH (>12.5 mIU/mL in follicular phase) suggests poor ovarian reserve, approaching menopause, or primary ovarian failure; Low FSH may indicate hypopituitarism or suppressed ovulation; Persistently elevated postmenopausal FSH confirms menopause
    • LH Interpretation: Elevated LH with normal FSH and elevated testosterone suggests PCOS; Absence of LH surge indicates anovulation; Elevated postmenopausal LH confirms menopause; LH:FSH ratio >2:1 or >3:1 may indicate PCOS; Low LH suggests hypothalamic or pituitary dysfunction
    • Prolactin Interpretation: Elevated prolactin (>29 ng/mL) causes galactorrhea, amenorrhea, anovulation, and reduced fertility; Mild elevation may indicate stress or pituitary microadenoma; Severe elevation (>200 ng/mL) suggests macroprolactinoma; Normal prolactin permits normal ovulation
    • Estradiol Interpretation: Low follicular phase estradiol (<24 pg/mL) indicates poor ovarian reserve or inadequate follicle development; Absence of ovulatory surge suggests anovulation; High basal estradiol may indicate PCOS or ongoing follicular development; Low postmenopausal estradiol expected and normal
    • Total T3 Interpretation: Low T3 (<80 ng/dL) indicates hypothyroidism, impaired conversion, or sick euthyroid syndrome; Elevated T3 (>200 ng/dL) suggests hyperthyroidism or T3 toxicosis; Low T3 impairs fertility and metabolism
    • Total T4 Interpretation: Low T4 (<4.5 μg/dL) indicates primary or secondary hypothyroidism; Elevated T4 (>11 μg/dL) suggests hyperthyroidism or thyroiditis; Abnormal T4 affects metabolism and reproductive function
    • TSH Interpretation: Elevated TSH (>4.0 mIU/L) indicates primary hypothyroidism; Low TSH (<0.4 mIU/L) suggests hyperthyroidism or secondary hypothyroidism; TSH imbalance disrupts menstrual cycles and fertility; Optimal fertility TSH is 0.5-2.5 mIU/L
    • AMH Interpretation: AMH >2.5 ng/mL indicates good ovarian reserve; AMH 0.7-2.5 ng/mL indicates normal ovarian reserve; AMH <0.7 ng/mL suggests diminished ovarian reserve; Very low AMH (<0.3 ng/mL) indicates severely compromised fertility potential; AMH independent of menstrual cycle phase
    • Unconjugated Estriol (E3) Interpretation: Low E3 in second trimester (<0.7 ng/mL or <0.5 MoM) associated with Down syndrome (Trisomy 21) and Edward syndrome (Trisomy 18); Low E3 may indicate placental dysfunction or fetal abnormalities; Results interpreted as multiple of median (MoM) relative to gestational age
    • Factors affecting results: Time of day (hormones show circadian variation), menstrual cycle phase, stress, sleep deprivation, medications (birth control pills suppress FSH/LH), recent exercise, body weight changes, and illness can all influence hormone levels
  • Associated Organs
    • FSH, LH, and Prolactin: Primarily evaluate the anterior pituitary gland and hypothalamus; secondary evaluation of ovarian function and reproductive axis; help diagnose pituitary adenomas, hypopituitarism, Sheehan syndrome, and central hypogonadism
    • Estradiol: Assesses ovarian function and estrogen production capacity; indicates follicular development and corpus luteum function; abnormal levels suggest ovarian dysfunction, premature ovarian failure, or polycystic ovary syndrome (PCOS)
    • Thyroid Profile (T3, T4, TSH): Evaluates thyroid gland function and pituitary-thyroid axis; abnormalities affect metabolism, fertility, menstrual regularity, and mood; thyroid disorders like Hashimoto's thyroiditis and Graves' disease impact reproductive health
    • Anti-Müllerian Hormone (AMH): Produced by granulosa cells of growing follicles in the ovaries; directly reflects ovarian reserve status and egg quantity; independent marker of ovarian aging and menopause timing; evaluates premature ovarian insufficiency (POI) and menopause prediction
    • Unconjugated Estriol (E3): Produced by both fetal liver and placenta; assesses placental function and fetal well-being; low levels indicate potential fetal chromosomal abnormalities or placental insufficiency; helps evaluate pregnancy complications
    • Associated conditions from abnormal results: Infertility, PCOS, primary ovarian insufficiency (POI), premature menopause, hypothyroidism, hyperthyroidism, pituitary adenomas, amenorrhea, anovulation, endometriosis, uterine fibroids, and chromosomal fetal abnormalities
    • Potential complications: Untreated hormonal imbalances can result in chronic anovulation, infertility, osteoporosis, cardiovascular disease, metabolic syndrome, depression, and compromised pregnancy outcomes
  • Follow-up Tests
    • If FSH/LH abnormal: Obtain free testosterone, DHEA-S, and 17-hydroxyprogesterone to evaluate for androgen excess or adrenal dysfunction; consider pituitary imaging (MRI) if markedly abnormal
    • If Prolactin elevated: Order pituitary MRI to rule out prolactinoma; repeat prolactin after excluding medications causing elevation; measure free thyroxine and TSH to exclude secondary hyperprolactinemia from hypothyroidism
    • If Estradiol low in follicular phase: Obtain progesterone level (day 21) to confirm anovulation; consider transvaginal pelvic ultrasound to assess ovarian morphology and follicle development; repeat hormonal panel next cycle
    • If Thyroid abnormal: Order TPO (thyroid peroxidase) and anti-thyroglobulin antibodies if TSH elevated to diagnose autoimmune thyroiditis; obtain thyroid ultrasound if TSH very abnormal; monitor thyroid function every 6-8 weeks if starting thyroid replacement
    • If AMH low (<0.7 ng/mL): Consider antral follicle count (AFC) on transvaginal ultrasound for additional ovarian reserve assessment; repeat AMH testing in 3-6 months; evaluate for premature ovarian insufficiency (POI) with additional testing
    • If E3 low in pregnancy: Obtain comprehensive maternal serum screening with alpha-fetoprotein (AFP), hCG (human chorionic gonadotropin), and inhibin A; consider genetic counseling and detailed fetal ultrasound; discuss amniocentesis or non-invasive prenatal testing (NIPT) options
    • Progesterone level: Measure mid-luteal phase (day 21 of 28-day cycle) to confirm ovulation; normal >5 ng/mL indicates ovulatory cycle occurred
    • Transvaginal pelvic ultrasound: Assess ovarian morphology, follicle number, and uterine pathology; evaluate for PCOS, endometriosis, fibroids, or ovarian cysts
    • Semen analysis: If abnormal hormones and infertility evaluation, assess male partner fertility factors concurrently
    • Repeat testing: Recommended every 3-6 months if on hormone therapy or for monitoring chronic conditions; after any medication changes; or if initial results inconclusive
  • Fasting Required?
    • Fasting: Not strictly required for the Female Hormone Package tests, though fasting is acceptable and does not interfere with results
    • Recommended fasting duration: If fasting, maintain 8-12 hours of fasting period; however, this is optional for hormone testing as these tests are not affected by recent food intake
    • Medication considerations: Discontinue hormonal contraceptives (birth control pills, patches, rings) for 3 months before testing if evaluating natural hormone levels, or specifically test while on contraceptives if assessing breakthrough bleeding; consult physician before stopping medications
    • Medications to discuss with provider: Thyroid medications, dopamine agonists, metformin, spironolactone, and other endocrine-active medications should be noted; continue these unless specifically instructed to discontinue
    • Timing considerations: Schedule FSH, LH, Estradiol, and Prolactin testing on days 2-5 of menstrual cycle (follicular phase) for accurate baseline assessment unless specifically instructed for other cycle phases; AMH testing timing is flexible and can be performed any day of the cycle
    • Testing time: Morning blood draw (8:00-10:00 AM) preferred as some hormones show circadian variation; consistent timing helps standardize results
    • Other preparation requirements: Avoid strenuous exercise 24 hours before testing as excessive activity affects hormone levels; minimize stress before testing; obtain adequate sleep night before collection; avoid caffeine if possible within 1-2 hours of draw
    • For prenatal E3 testing: Fasting not required; optimal timing is 16-18 weeks gestation as part of quad screen or other second trimester screening protocols; accurate gestational age dating crucial for result interpretation
    • Special circumstances: If on hormone replacement therapy (HRT), document type and dose; discuss timing of testing relative to HRT administration; inform laboratory of any supplements or herbal products being used as some contain phytohormones

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