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First Milk Blood

Pregnancy
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Report in 96Hrs

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At Home

nofastingrequire

No Fasting Required

Details

Tests newborn’s first milk/blood.

₹1,110₹1,586

30% OFF

First Milk Blood Test - Comprehensive Information Guide

  • Why is it done?
    • Measures blood biomarkers present in colostrum (first milk) to assess neonatal immune function and maternal-fetal antibody transfer
    • Evaluates the quality and protective capacity of colostrum for newborn passive immunity
    • Typically performed within the first 12-24 hours postpartum during initial breastfeeding
    • Used to identify inadequate colostral quality that may necessitate supplementation or intervention
    • Assesses immunoglobulin levels, particularly IgA and IgG, critical for neonatal protection
    • Monitors maternal antibody transmission, especially in immunocompromised or vaccination-status unclear mothers
  • Normal Range
    • Immunoglobulin A (IgA): >100 mg/dL or >1000 mg/L (considered adequate for neonatal protection)
    • Immunoglobulin G (IgG): >500 mg/dL (indicates strong maternal antibody transfer)
    • Immunoglobulin M (IgM): >50 mg/dL (typically low in colostrum)
    • Total Protein: >5.5 g/dL (indicates adequate colostral composition)
    • Normal Results Interpretation: Adequate immunological quality of colostrum with sufficient maternal antibodies for neonatal protection
    • Low/Abnormal Results: Values below reference ranges indicate reduced colostral quality and decreased passive immunity transfer, potentially requiring intervention
  • Interpretation
    • High Immunoglobulin Levels (IgA >1000 mg/L): Indicates excellent colostral quality with strong maternal antibody transfer; optimal protection for newborn against pathogens
    • Borderline Immunoglobulin Levels (IgA 50-100 mg/dL): Moderate passive immunity; warrants monitoring; may require colostrum supplementation or close neonatal observation
    • Low Immunoglobulin Levels (IgA <50 mg/dL): Inadequate colostral quality; increased neonatal infection risk; requires supplementation with donor colostrum or immune support
    • Elevated IgM in Colostrum: May indicate maternal acute infection or immune activation; suggests need for neonatal assessment
    • Factors Affecting Results: Maternal health status, nutritional state, infections, immunization history, gestational age, delivery method, and timing of sample collection
    • Clinical Significance: Critical for determining adequacy of passive immunity in breastfed neonates and guiding feeding interventions
  • Associated Organs
    • Primary Organ Systems: Mammary glands (breast tissue), lymphatic system, immune system (B cells and plasma cells in mammary tissue)
    • Secondary Organ Systems: Gastrointestinal tract (neonatal), liver, bone marrow
    • Conditions Associated with Abnormal Results: Maternal immunodeficiency, HIV/AIDS, autoimmune disorders, chronic infections, malnutrition, premature birth, maternal diabetes, preeclampsia
    • Associated Neonatal Complications: Neonatal infections (sepsis, gastroenteritis, respiratory tract infections), increased susceptibility to pathogens, failure to thrive, necrotizing enterocolitis
    • Maternal Health Implications: Abnormal results may indicate underlying maternal immune dysfunction, recent infections, or systemic disease requiring maternal evaluation
  • Follow-up Tests
    • If Low Immunoglobulin Levels: Serum immunoglobulin levels in maternal blood, maternal infectious disease screening (HIV, Hepatitis B/C, syphilis), neonatal immunoglobulin levels
    • Neonatal Assessment Tests: Complete blood count, neonatal serum immunoglobulin levels, pathogen-specific antibody titers (pertussis, measles, varicella if indicated)
    • Infectious Disease Screening: Maternal serologic testing if acute infection suspected, neonatal infection workup (blood and urine cultures), viral PCR studies
    • Repeat Colostrum Testing: May be repeated at 24-48 hours to assess changes in colostral composition as transition to mature milk occurs
    • Lactation Consultation: Lactation specialist evaluation to optimize milk production and quality; assess breastfeeding technique
    • Complementary Immunological Tests: Maternal immunoglobulin panel, lymphocyte subsets, complement function studies if immunodeficiency suspected
    • Monitoring Frequency: If supplementation required, reassess colostral quality after interventions; monitor neonatal health for first 3-6 months of life
  • Fasting Required?
    • Fasting Requirement: NO - Fasting is not required for First Milk Blood testing
    • Sample Collection Timing: Collect colostrum sample within first 12-24 hours postpartum; optimal timing is within 6 hours of delivery when colostral composition is most concentrated
    • Patient Preparation Instructions: Nurse breasts gently and warm with warm compress if needed to facilitate sample collection; collect from both breasts if possible for representative sample
    • Special Collection Precautions: Use sterile collection containers; disinfect nipple area with 70% alcohol and allow to dry; do not use antibacterial soap; avoid contamination with maternal skin bacteria
    • Medications/Supplements: No medications need to be withheld; document any recent maternal medications or vaccinations on the test requisition as they may affect immunoglobulin levels
    • Sample Storage and Transport: Keep sample refrigerated at 2-8°C if transport is delayed; process within 2 hours of collection for optimal results; do not freeze unless specified by laboratory
    • Additional Considerations: Maternal hydration status does not affect test validity; colostrum composition is not significantly influenced by maternal recent food or fluid intake

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