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FOOD + INHALANTS + DRUG ALLERGY SCREENING TESTS(BY IMMUNO- EIA)
Allergy
Report in 72Hrs
At Home
No Fasting Required
Details
Screening panels for allergens.
₹4,440₹6,343
30% OFF
FOOD + INHALANTS + DRUG ALLERGY SCREENING TESTS (BY IMMUNO-EIA)
- Why is it done?
- Detects IgE antibodies against specific allergens including food proteins, inhalant particles, and pharmaceutical agents using enzyme immunoassay (EIA) technology
- Identifies allergic sensitization in patients with suspected IgE-mediated allergic reactions
- Diagnoses food allergies (peanuts, tree nuts, shellfish, milk, eggs, wheat, soy, fish)
- Evaluates inhalant allergies (dust mites, pollen, mold spores, pet dander, cockroach)
- Detects drug allergies and hypersensitivities (penicillin, cephalosporins, NSAIDs, antibiotics)
- Useful when skin testing is contraindicated or inconclusive
- Performed to establish diagnosis before allergen immunotherapy or to guide avoidance strategies
- Normal Range
- Units: kIU/L (kilointernational units per liter) or IU/mL
- Negative/Normal Result: < 0.35 kIU/L - Indicates no significant IgE sensitization to the tested allergen
- Borderline/Possible: 0.35 - 0.69 kIU/L - Weak sensitization; may require clinical correlation
- Class 1 (Low): 0.70 - 3.50 kIU/L - Low allergen-specific IgE
- Class 2 (Moderate): 3.51 - 17.50 kIU/L - Moderate allergen-specific IgE
- Class 3 (High): 17.51 - 52.00 kIU/L - High allergen-specific IgE
- Class 4 (Very High): 52.01 - 100.00 kIU/L - Very high allergen-specific IgE
- Class 5 (Extremely High): > 100.00 kIU/L - Extremely high allergen-specific IgE
- Higher values correlate with increased likelihood of clinical allergic reaction but do not always predict severity
- Interpretation
- Positive Results (≥ 0.35 kIU/L): Indicates IgE-mediated sensitization to the specific allergen tested; suggests potential for allergic reactions upon exposure
- Negative Results (< 0.35 kIU/L): Suggests no IgE-mediated allergy to tested allergen; does not rule out non-IgE mediated reactions or delayed hypersensitivity
- Higher Quantitative Values: Class 3-5 results indicate stronger sensitization and higher risk of symptomatic reactions; may predict severity and guide treatment intensity
- Multiple Positive Allergens: May indicate polyallergy or cross-reactivity patterns; requires comprehensive avoidance strategy
- Clinical Correlation Essential: Results must be interpreted with patient history, symptoms, and exposure patterns; positive test does not always mean clinical allergy
- Factors Affecting Results:
- Recent antihistamine use may suppress results
- Immunosuppressive therapy may cause false-negative results
- Acute systemic anaphylaxis may temporarily decrease IgE levels
- Atopic individuals may have elevated baseline IgE levels
- Cross-reactivity between related allergens can cause multiple positive results
- Associated Organs
- Primary Organ Systems:
- Immune system (produces IgE antibodies)
- Respiratory system (bronchial asthma, rhinitis, laryngeal edema)
- Gastrointestinal system (food allergies, GI symptoms)
- Cutaneous system (urticaria, angioedema, dermatitis)
- Diseases and Conditions Associated with Positive Results:
- IgE-mediated food allergies (anaphylaxis risk)
- Allergic asthma and reactive airway disease
- Allergic rhinitis and nasal polyps
- Atopic dermatitis and eczema
- Urticaria and angioedema
- Drug hypersensitivity reactions
- Occupational allergies and latex allergy
- Insect sting hypersensitivity
- Potential Complications:
- Anaphylaxis (life-threatening systemic reaction)
- Acute respiratory distress and bronchospasm
- Severe angioedema with airway compromise
- Nutritional deficiencies from food avoidance
- Follow-up Tests
- Confirmatory Tests:
- Skin prick testing (SPT) - gold standard for allergy diagnosis
- Intradermal skin testing (for drug allergies and diagnostically unclear cases)
- Oral food challenge test (OFC) - definitive test for food allergies
- Drug challenge test (graded dose or open challenge)
- Complementary Tests:
- Total IgE serum level - helps assess overall atopic status
- Complete blood count (CBC) with differential - assess eosinophil counts
- Pulmonary function testing (PFTs) - for inhalant allergy with respiratory symptoms
- Component-resolved diagnostics (CRD) - for detailed protein allergen profiling
- Measurement of allergen-specific IgG/IgG4 (for monitoring immunotherapy)
- Diagnostic Imaging:
- Chest X-ray - if respiratory involvement suspected
- Sinus CT scan - for chronic rhinosinusitis related to allergies
- Monitoring and Surveillance:
- Repeat specific IgE testing annually for patients on immunotherapy to assess response
- Follow-up testing if clinical presentation changes despite avoidance
- Periodic reassessment in pediatric cases (tolerance may develop with age)
- Fasting Required?
- Fasting: No
- Fasting is not required for this blood test
- Patient Preparation Instructions:
- Discontinue antihistamine medications (H1 and H2 blockers) for 7-14 days before testing when possible, as they can suppress reactions
- Stop topical corticosteroids on affected areas at least 2 weeks prior
- If possible, avoid immunosuppressive therapy or discuss with physician regarding timing of testing
- Continue regular medications unless specifically instructed otherwise by physician
- Regular meals and hydration are recommended; bring photo identification and insurance card
- For drug allergy testing specifically, document all current and recently used medications
- Inform phlebotomist if recent acute allergic reaction occurred within past 2 weeks
How our test process works!
