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Glucose 3 hr (4 Samples)

Diabetes
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Report in 24Hrs

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At Home

fastingrequire

Fasting Required

Details

Checks glucose metabolism.

₹148₹211

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Glucose 3 hr (4 Samples) - Comprehensive Test Information Guide

  • Why is it done?
    • The Glucose 3-hour tolerance test measures blood glucose levels at timed intervals (typically fasting, 1 hour, 2 hours, and 3 hours) to assess how your body processes and regulates blood sugar over time
    • Primary indication: Screening and diagnosis of gestational diabetes mellitus (GDM) in pregnant women, typically performed between 24-28 weeks of gestation
    • Evaluation of glucose tolerance abnormalities and impaired fasting glucose in non-pregnant individuals
    • Assessment of Type 2 diabetes risk or confirmation of diabetes diagnosis in symptomatic patients
    • Investigation of reactive hypoglycemia or abnormal glucose metabolism in patients with suggestive symptoms
    • Performed after abnormal results on initial screening test (usually 1-hour glucose challenge test in pregnancy)
  • Normal Range
    • Units of measurement: Milligrams per deciliter (mg/dL) or millimoles per liter (mmol/L)
    • For Gestational Diabetes Screening (3-hour test): Normal results typically require at least 2 values to be within normal range (not meeting gestational diabetes criteria)
    • Fasting glucose: Less than 95 mg/dL (5.3 mmol/L)
    • 1-hour glucose: Less than 180 mg/dL (10.0 mmol/L)
    • 2-hour glucose: Less than 155 mg/dL (8.6 mmol/L)
    • 3-hour glucose: Less than 140 mg/dL (7.8 mmol/L)
    • For General Glucose Tolerance Testing: Fasting: 70-100 mg/dL; 2-hour value below 140 mg/dL is considered normal glucose tolerance
    • Interpretation: Normal results indicate appropriate glucose metabolism and absence of diabetes or gestational diabetes; borderline or elevated values suggest impaired glucose tolerance or diabetes
  • Interpretation
    • Normal Test Results: All four values fall within normal range; indicates normal glucose tolerance and appropriate insulin response; rules out gestational diabetes or Type 2 diabetes
    • Gestational Diabetes Diagnosis: Two or more values at or above the threshold levels; pregnancy-related glucose intolerance requiring management and monitoring
    • Impaired Glucose Tolerance (IGT): 2-hour value 140-199 mg/dL; indicates prediabetic state with increased risk for Type 2 diabetes development
    • Type 2 Diabetes: 2-hour value ≥200 mg/dL or fasting ≥126 mg/dL; diagnostic of diabetes mellitus requiring treatment initiation
    • Reactive Hypoglycemia: Excessive glucose decline at 1-2 hours followed by values below 70 mg/dL; suggests delayed insulin response causing symptomatic hypoglycemia
    • Factors Affecting Interpretation:
    • Recent illness, stress, or infections can elevate glucose levels
    • Physical activity levels and diet composition in days preceding test
    • Medications (corticosteroids, thiazide diuretics, beta-blockers) may affect results
    • Body weight and obesity status influence glucose metabolism
    • Gestational age affects glucose tolerance thresholds in pregnancy
    • Polycystic ovary syndrome (PCOS) and other endocrine disorders impact glucose handling
  • Associated Organs
    • Primary Organ Systems:
    • Pancreas: Produces insulin in response to glucose; dysfunction or beta cell failure leads to impaired glucose control
    • Liver: Stores and regulates glucose release; affected in liver disease, cirrhosis, or hepatic insufficiency
    • Kidneys: Filter glucose; impaired renal function affects glucose clearance and test interpretation
    • Endocrine system: Hormones (cortisol, glucagon, thyroid hormones) regulate glucose metabolism
    • Associated Conditions and Diseases:
    • Gestational diabetes mellitus: Temporary glucose intolerance during pregnancy affecting fetal development and maternal health
    • Type 2 diabetes mellitus: Progressive loss of insulin sensitivity and beta cell function
    • Impaired glucose tolerance (prediabetes): Intermediate glucose metabolism disorder
    • Reactive hypoglycemia: Excessive insulin response causing post-prandial glucose drops
    • Cushing's syndrome: Excess cortisol increases glucose production and reduces insulin sensitivity
    • Acromegaly: Growth hormone excess impairs glucose tolerance
    • Polycystic ovary syndrome (PCOS): Associated with insulin resistance and impaired glucose tolerance
    • Potential Complications from Abnormal Results:
    • Diabetic ketoacidosis (DKA): Life-threatening metabolic emergency from severe hyperglycemia
    • Hyperosmolar hyperglycemic state: Severe dehydration and hyperglycemia in Type 2 diabetes
    • Severe hypoglycemia: Neurological damage or loss of consciousness from excessive glucose depletion
    • Long-term diabetic complications: Neuropathy, nephropathy, retinopathy, cardiovascular disease
    • Fetal complications in gestational diabetes: Macrosomia, birth trauma, neonatal hypoglycemia, respiratory distress
  • Follow-up Tests
    • If Gestational Diabetes Confirmed:
    • Home blood glucose monitoring: Daily self-monitoring of fasting and post-meal glucose levels
    • Hemoglobin A1C (HbA1C): Assessment of average glucose control over 3-month period
    • Fasting glucose and random glucose: Regular monitoring every 1-2 weeks during pregnancy
    • Fetal ultrasound: Assessment of fetal growth, amniotic fluid volume, and biophysical profile
    • Postpartum glucose tolerance test: 6-week post-delivery retesting to assess persistent diabetes
    • If Type 2 Diabetes or IGT Diagnosed:
    • Hemoglobin A1C: Baseline and every 3 months to monitor glycemic control targets
    • Lipid panel: Assessment of cholesterol and triglyceride levels for cardiovascular risk
    • Comprehensive metabolic panel: Renal function, electrolytes, and liver function assessment
    • Urinalysis and microalbumin: Screening for early diabetic nephropathy
    • Fasting glucose and C-peptide: Assessment of residual beta cell function
    • Retinal screening exam: Ophthalmologic evaluation for diabetic retinopathy
    • Monofilament testing: Foot examination for diabetic neuropathy assessment
    • If Reactive Hypoglycemia Suspected:
    • Insulin levels (simultaneous with glucose): Assessment of insulin response appropriateness
    • Extended glucose tolerance test: Prolonged monitoring to 4-5 hours for delayed hypoglycemic responses
    • Continuous glucose monitoring (CGM): Real-time glucose trends and symptomatic correlation
    • General Monitoring Frequency:
    • Gestational diabetes: Weekly to biweekly glucose monitoring and monthly HbA1C through delivery
    • Type 2 diabetes newly diagnosed: HbA1C every 3 months until stable, then every 6-12 months; metabolic panel annually
    • Prediabetes/IGT: Repeat glucose tolerance testing annually; HbA1C every 6-12 months
  • Fasting Required?
    • Yes - Fasting is required.
    • Duration: 8-10 hours overnight fasting before the initial fasting glucose sample
    • Fasting Instructions:
    • No food or beverages except water for 8-10 hours preceding the test start
    • Typically performed in early morning after overnight fasting
    • Drink 75-100 grams of glucose solution after fasting blood draw (or 50-100g per protocol)
    • No eating, drinking (except water), or smoking during the 3-hour test period
    • Remain sitting or lying down during test period; avoid vigorous exercise
    • Medications to Avoid or Discuss:
    • Corticosteroids: Can increase glucose levels; discuss with provider about temporary discontinuation
    • Thiazide diuretics: May elevate glucose; notify provider before test
    • Beta-blockers: Can mask hypoglycemia symptoms; discuss test timing with provider
    • Oral contraceptives: May slightly elevate glucose; continue as prescribed
    • Caffeine: Avoid for 24-30 hours before test as it may affect glucose levels
    • Other Patient Preparation Requirements:
    • Maintain normal diet for 3 days prior to test (not low-carbohydrate diet)
    • Ensure adequate physical activity and normal sleep patterns before testing
    • Avoid stress and illness within 3 days of test if possible
    • Reschedule test if patient has acute infection, fever, or recent illness
    • Wear loose, comfortable clothing for easy blood draws; bring identification and insurance
    • Arrive 10-15 minutes early to allow for check-in and baseline vital signs
    • Plan for 3-4 hour time commitment at the testing facility
    • Bring entertainment or reading materials for waiting periods between blood draws

How our test process works!

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