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HCV Card test

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It is used for screening for Hepatitis C virus (HCV) exposure

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🧪 What is the HCV Card Test?

The HCV Card Test is a rapid immunochromatographic assay used to detect anti-HCV antibodies in human blood, serum, or plasma.

  • It is used for screening for Hepatitis C virus (HCV) exposure.
  • Results are usually available within 15–20 minutes.

This test does not detect the virus itself, but antibodies produced in response to infection.

❓ Why is the Test Done?

To:

  • Screen for Hepatitis C infection, especially in high-risk individuals
  • Check HCV exposure in blood donors, pregnant women, surgical candidates
  • Initiate further testing if positive
  • Aid in public health screening campaigns

📊 Normal Range / Expected Results

Result

Interpretation

Negative / Non-reactive

No anti-HCV antibodies detected → Likely no HCV exposure

Positive / Reactive

Anti-HCV antibodies detected → Indicates past or present HCV infection

⚠️ Positive results must be confirmed with HCV RNA PCR to detect active infection.

📈 Interpretation of Results

Test Result

Meaning

Negative

No evidence of prior or current infection (unless in early window period)

Positive

Exposure to HCV virus – could be a resolved, chronic, or false-positive infection

False Negatives

May occur in early infection or immunocompromised patients

False Positives

Possible due to cross-reactions – always confirm with PCR

🧠 Associated Organs & Conditions

Organ

Conditions

Liver

Hepatitis C (acute or chronic), cirrhosis, hepatocellular carcinoma (HCC)

Immune System

Immune response generates detectable antibodies

🔄 Related / Follow-Up Tests

  1. HCV RNA PCR (Qualitative) – To confirm active infection
  2. HCV RNA PCR (Quantitative) – Measures viral load
  3. HCV Genotyping – To guide treatment
  4. Liver Function Tests (ALT, AST, bilirubin)
  5. FibroScan / Liver biopsy – For fibrosis staging
  6. Alpha-Fetoprotein (AFP) – To screen for HCC

✅ Fasting Required?

Test

Fasting Requirement

HCV Card Test

❌ No fasting required – Can be performed at any time of day

📝 Summary Table

Parameter

Details

What

Rapid card test to detect anti-HCV antibodies in blood/serum

Why

Initial screening for Hepatitis C virus exposure

Normal Result

Negative / Non-reactive

Positive Result

Exposure to HCV — needs PCR confirmation

Follow-up Tests

HCV RNA PCR, genotyping, LFTs, liver scan

Associated Conditions

Hepatitis C, cirrhosis, liver cancer

Fasting Required

❌ No

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