Hepatitis Panel

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45 parameters

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Viral hepatitis screening panel.

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Parameters

Anti-HCV IgM (Hepatitis C Virus)
- Why is it done?
  - To detect recent or ongoing Hepatitis C infection
  - Typically ordered with or after HCV RNA testing
  - May support diagnosis in symptomatic patients
- Normal Range
  - Negative: No acute HCV infection
  - Positive: Suggests recent or active HCV infection
- Interpretation
  - Negative: No recent HCV infection or early window period
  - Positive: Likely acute or recent HCV infection Note: IgM testing for HCV has limited sensitivity; HCV RNA PCR is the gold standard
- Associated Organs
  - Liver: Hepatitis, cirrhosis, liver failure
  - Risk of chronic infection
- Follow-up Tests:
  - HCV RNA PCR (qualitative and quantitative)
  - HCV Genotyping
  - LFTs (ALT, AST, Bilirubin)
  - Anti-HCV Total
- Fasting Required? No
Anti-HAV IgM (Hepatitis A Virus)
- Why is it done?
  - To diagnose acute hepatitis A
  - Symptoms: nausea, fatigue, jaundice, fever, elevated liver enzymes
- Normal Range
  - Negative: No current Hepatitis A
  - Positive: Recent/acute Hepatitis A infection
- Interpretation
  - Negative: No recent HAV exposure
  - Positive: Active or very recent HAV infection
  - IgM appears within 2–3 weeks of infection and declines after ~3 months
- Associated Organs
  - Liver – self-limited hepatitis, rarely fulminant
- Follow-up Tests
  - LFTs (ALT, AST, Bilirubin)
  - HAV Total (IgM + IgG for past exposure/immunity)
- Fasting Required? No
Anti-HBc IgM (Hepatitis B Core Antibody - IgM)
- Why is it done?
  - Detects acute Hepatitis B infection
  - Useful when HBsAg is positive and differentiating acute vs chronic HBV
- Normal Range
  - Negative: No acute HBV infection
  - Positive: Acute or recent HBV infection
- Interpretation
  - Negative: No acute infection
  - Positive: Indicates acute HBV infection or reactivation
  - Appears early and disappears in 6 months; its presence strongly suggests acute Hep B
- Associated Organs
  - Liver: Acute hepatitis B, fulminant hepatitis
- Follow-up Tests
  - HBsAg
  - HBeAg
  - HBV DNA PCR
  - LFTs
- Fasting Required? No
Anti-HEV IgM (Hepatitis E Virus)
- Why is it done?
  - To diagnose acute Hepatitis E infection, especially in:
    - Pregnant women
    - Travelers
    - Outbreak zones with poor sanitation
- Normal Range
  - Negative: No acute infection
  - Positive: Suggests recent or ongoing infection
- Interpretation
  - Negative: No current HEV infection
  - Positive: Recent or active HEV infection
  - IgM appears during acute phase, declines in weeks
- Associated Organs & Risks
  - Liver: Acute hepatitis
  - Pregnancy: High mortality if infected in 3rd trimester
- Follow-up Tests
  - LFTs
  - Anti-HEV IgG
  - HEV RNA (rarely)
- Fasting Required? No

Summary Table

Test	What It Detects	Use Case	Positive Means	Fasting
Anti-HCV IgM	HCV-specific IgM antibodies	Acute Hepatitis C suspicion	Recent or ongoing HCV infection	No
Anti-HAV IgM	HAV-specific IgM antibodies	Acute Hepatitis A diagnosis	Current Hepatitis A infection	No
Anti-HBc IgM (Anti-Hep B Core IgM)	HBV Core-specific IgM	Differentiate acute vs chronic HBV	Acute Hepatitis B	No
Anti-HEV IgM	HEV-specific IgM antibodies	Hepatitis E suspicion (esp. pregnancy)	Recent/active HEV infection	NO

How our test process works!