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Leg swelling - Large Biopsy 3-6 cm

Biopsy
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Report in 288Hrs

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At Home

nofastingrequire

No Fasting Required

Details

Biopsy of soft tissue or ulcers.

₹666₹951

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Leg Swelling - Large Biopsy 3-6 cm

  • Why is it done?
    • To obtain tissue samples from leg lesions, nodules, or abnormal growths measuring 3-6 cm in diameter
    • To diagnose suspicious skin lesions, including melanoma, squamous cell carcinoma, and other malignancies
    • To evaluate subcutaneous nodules, lipomas, cysts, or other benign and malignant lesions
    • To assess lymph node enlargement in the leg region
    • To determine the nature of chronic leg swelling when imaging is inconclusive
    • Performed when smaller needle biopsies are inadequate or when larger tissue samples are required for accurate diagnosis
  • Normal Range
    • Normal Result: Absence of malignant cells, benign tissue characteristics consistent with diagnosis, no evidence of infection or atypical cellular features
    • Benign Findings: Lipoma, cyst, inflammatory tissue, benign nevus, fibrotic tissue, or normal subcutaneous fat
    • Interpretation: Results are reported as categorical findings rather than numerical values
    • Pathology grading may include: benign, atypical, suspicious, or malignant
    • Negative Result: No malignancy detected; no need for immediate urgent intervention
  • Interpretation
    • Benign Diagnosis: Indicates non-cancerous tissue; reassurance provided; clinical follow-up as needed based on specific diagnosis (e.g., lipoma may not require further intervention)
    • Atypical Findings: Abnormal but not definitively malignant; may require re-biopsy, excision, or close clinical monitoring with repeat imaging
    • Malignant Diagnosis: Indicates cancer present; requires urgent treatment planning including oncology consultation, staging, and therapeutic intervention
    • Specific Cancer Types: Melanoma, squamous cell carcinoma, basal cell carcinoma, lymphoma, or other identified malignancy with grade and stage information
    • Infectious Process: May reveal bacterial, fungal, or parasitic infection; guides antimicrobial therapy decisions
    • Factors Affecting Interpretation: Tissue preservation quality, specimen adequacy, patient factors (immunosuppression, prior treatments), and biopsy location from representative area
  • Associated Organs
    • Primary: Skin and subcutaneous tissue of the lower extremities; superficial and deep leg structures
    • Secondary: Lymph nodes, muscles, and connective tissue of the lower leg
    • Common Diagnoses: Melanoma, squamous cell carcinoma, lipoma, dermoid cyst, hemangioma, lymphangioma, fibroma, sarcoma
    • Infectious Conditions: Cellulitis, abscess, tuberculosis verrucosa cutis, atypical mycobacterial infections
    • Systemic Conditions: Lymphoma presentation in leg, sarcoidosis, vasculitis affecting lower extremities
    • Complications: Infection, bleeding, hematoma formation, permanent scarring, nerve damage, delayed wound healing
  • Follow-up Tests
    • If Malignancy Confirmed: Staging CT scan (chest, abdomen, pelvis), MRI of involved area, PET-CT scan for systemic evaluation
    • Immunohistochemistry and Flow Cytometry: For tumor classification, prognosis determination, and treatment planning
    • Molecular Testing: Gene mutation analysis (BRAF, KIT, NRAS for melanoma), sentinel lymph node biopsy if indicated
    • If Atypical: Excision biopsy with wider margins, repeat biopsy after 4-6 weeks, ultrasound or MRI monitoring
    • If Infection Identified: Culture and sensitivity testing, antibiotic therapy initiation, repeat imaging in 2-4 weeks
    • If Benign: Clinical observation, imaging follow-up at 3-6 months if lesion size changes or symptoms develop
    • Dermatology or Oncology Consultation: Recommended for all malignant diagnoses and complex cases
  • Fasting Required?
    • No fasting is required for this biopsy procedure
    • Pre-Procedure Instructions: Continue normal diet and medications unless specifically instructed otherwise by your physician
    • Medications to Avoid: Discontinue blood thinners (warfarin, clopidogrel, aspirin) 3-5 days before procedure if possible; consult with physician
    • Preparation: Bathe or shower the night before; wear loose, comfortable clothing allowing access to biopsy site
    • Day of Procedure: Arrive 15 minutes early; bring insurance cards and identification; avoid applying lotion or makeup to biopsy site
    • Post-Procedure Care: Keep biopsy site clean and dry; avoid strenuous activity for 24-48 hours; follow wound care instructions provided

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