🧪 What is the Leptospira IgM Test?

The Leptospira IgM test detects Immunoglobulin M (IgM) antibodies in the blood that are produced in early response to Leptospira infection—a zoonotic bacterial disease often spread through contaminated water or soil.

• IgM antibodies typically appear within 3–7 days of infection.
• It is commonly performed via ELISA or IFA.
• It is one of the most reliable early markers for acute leptospirosis.

❓ Why is the Test Done?

To:

• Diagnose early leptospiral infection, especially during the first 1–2 weeks of illness
• Evaluate febrile illnesses with unknown origin in endemic regions
• Identify occupational exposure in high-risk professions (farmers, sewage workers, veterinarians)
• Assess patients with renal, hepatic, or pulmonary symptoms after monsoon/flood exposure

📊 Normal Range

IgM may remain detectable for several weeks to months post-infection, so clinical correlation is essential.

📈 Interpretation of Results

For definitive diagnosis, a rising titer in paired samples or confirmation by PCR/MAT is preferred.

🧠 Associated Organs & Conditions

🔄 Related / Follow-Up Tests

• Leptospira IgG – for past or prolonged infection
• Leptospira IgM + IgG (Rapid) – screening tool
• PCR for Leptospira DNA – early-phase confirmation
• Microscopic Agglutination Test (MAT) – reference confirmatory test
• LFT, KFT – to assess liver/kidney damage
• CBC – thrombocytopenia, leukocytosis
• CRP, ESR – inflammatory markers

✅ Fasting Required?

📝 Summary Table