Leptospira IgM Rapid
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Detects IgM antibodies in the blood against Leptospira bacteria, which cause leptospirosis
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🧪 What is the Leptospira IgM Rapid Test?
The Leptospira IgM Rapid Test is a point-of-care, lateral flow immunoassay used to detect IgM antibodies against Leptospira in whole blood, serum, or plasma.
- IgM antibodies appear 3–7 days after infection.
- A positive result indicates a recent or active infection.
- The test provides quick results (within 15–20 minutes) and is useful in emergency or low-resource settings.
❓ Why is the Test Done?
To:
- Rapidly diagnose acute leptospirosis, especially in areas with limited access to lab facilities
- Identify early infection during outbreaks, especially in monsoon/flood seasons
- Support diagnosis in symptomatic individuals (e.g., fever, jaundice, kidney symptoms)
📊 Interpretation of Results
Result | Meaning |
|---|---|
Positive | Recent or current leptospiral infection |
Negative | No detectable IgM, very early or no infection |
False negatives may occur in the very early stage (<3 days) or immunocompromised patients.
False positives are possible due to cross-reactivity with other infections (e.g., dengue, malaria).
📈 Clinical Timeline of IgM Appearance
Infection Stage | IgM Result | Remarks |
|---|---|---|
0–3 Days | Likely Negative | Antibodies not yet detectable |
4–10 Days | Positive | Peak IgM response |
>2 Weeks | Positive | May persist for weeks/months |
🧠 Associated Organs & Complications
Organ/System | Associated Complications |
|---|---|
Kidneys | Acute kidney injury (Weil’s disease) |
Liver | Hepatitis, jaundice |
Lungs | Pulmonary hemorrhage, ARDS |
CNS | Aseptic meningitis, encephalitis |
Eyes | Uveitis, conjunctival suffusion |
🔄 Related / Follow-Up Tests
- Leptospira IgG – for past or prolonged infection
- Leptospira IgM ELISA – confirmation
- PCR for Leptospira DNA – early/acute detection
- MAT (Microscopic Agglutination Test) – gold standard
- Liver and Renal Function Tests (LFT, KFT)
- CBC – for thrombocytopenia or leukocytosis
✅ Fasting Required?
Test | Fasting Requirement |
|---|---|
Leptospira IgM Rapid | ❌ No |
📝 Summary Table
Parameter | Details |
|---|---|
What | Rapid test to detect IgM antibodies to Leptospira |
Why | Early diagnosis of acute leptospirosis |
Positive Result | Indicates recent/active infection |
Negative Result | No infection or very early stage |
Follow-up Tests | IgG, ELISA, PCR, MAT, LFT, KFT, CBC |
Organs Affected | Liver, kidneys, lungs, CNS |
Fasting Required | ❌ No |
How our test process works!
