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Magnesium

Unit Test
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Measures the concentration of magnesium in the blood.

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🧪 **What is the Magnesium Test?

**
The Serum Magnesium Test measures the concentration of magnesium in the blood.
Magnesium is an essential electrolyte and mineral required for:

  • Muscle and nerve function
  • Heart rhythm regulation
  • Bone strength
  • Enzyme activity and energy metabolism

Only ~1% of total body magnesium is present in blood; most is in bones and cells. Therefore, this test reflects extracellular magnesium levels.

❓ Why is the Test Done?

To:

  • Diagnose magnesium deficiency or excess
  • Evaluate neuromuscular symptoms (e.g., muscle cramps, tremors, seizures)
  • Monitor electrolyte imbalances
  • Assess renal function
  • Investigate cardiac arrhythmias
  • Monitor patients on diuretics, chemotherapy, or magnesium supplements

📊 Normal Range

Age/Group

Normal Serum Magnesium Range

Adults

1.6 – 2.6 mg/dL (0.66 – 1.07 mmol/L)

Children

1.6 – 2.5 mg/dL

Ranges may vary slightly depending on the lab.

📈 Interpretation of Results

Magnesium Level

Possible Causes / Conditions

↓ Low (<1.6 mg/dL)

Malnutrition, chronic alcoholism, diarrhea, vomiting, diuretics, diabetes, refeeding syndrome, PPIs

↑ High (>2.6 mg/dL)

Kidney failure, excessive supplementation, adrenal insufficiency, lithium toxicity

🧠 Associated Organs & Systems

System/Organ

Associated Conditions

Neuromuscular

Tetany, seizures, cramps, tremors

Cardiovascular

Arrhythmias, QT prolongation, hypotension

Renal

Impaired magnesium excretion in CKD

GI Tract

Malabsorption syndromes, chronic diarrhea

Endocrine

Diabetes, hyperparathyroidism

🔄 Related / Follow-Up Tests

  • Calcium (Serum) – often altered alongside magnesium
  • Phosphorus (Serum) – inverse relationship
  • Potassium (Serum) – low Mg can cause low K
  • Creatinine, BUN – for kidney function
  • ECG – if arrhythmias are suspected
  • Vitamin D and PTH – if metabolic abnormalities exist

✅ Fasting Required?

Test

Fasting Requirement

Magnesium

Not required

📝 Summary Table

Parameter

Details

What

Measures magnesium concentration in serum

Why

Diagnose deficiency, monitor renal/electrolyte status

Normal Range

1.6 – 2.6 mg/dL

Low Mg

Diarrhea, alcoholism, diuretics, diabetes

High Mg

CKD, supplements, lithium, adrenal issues

Follow-up Tests

Calcium, phosphorus, potassium, renal panel, ECG

Fasting Required

❌ No

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