Microalbumin 24 hours
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Total amount of albumin excreted in urine over 24 hours
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🧪 What is the Microalbumin – 24-Hour Urine Test?
This test measures the total amount of albumin excreted in urine over 24 hours to assess early kidney damage, especially in diabetics and hypertensive patients.
- Albumin is a protein that normally remains in the bloodstream.
- Elevated levels in urine (microalbuminuria) indicate early signs of kidney damage, even before serum creatinine or eGFR changes.
❓ Why is the Test Done?
To:
- Detect early kidney disease (especially in diabetes, hypertension)
- Monitor patients with known chronic kidney disease (CKD)
- Evaluate cardiovascular and renal risk
- Guide treatment to prevent progression of nephropathy
📦 How the 24-Hour Collection Works
- All urine is collected over a 24-hour period
- A total albumin output (mg/24 hours) is calculated
📊 Normal Range & Interpretation
Albumin in 24-Hour Urine | Interpretation |
|---|---|
< 30 mg/24 hr | Normal |
30–300 mg/24 hr | Microalbuminuria (early damage) |
> 300 mg/24 hr | Macroalbuminuria (significant damage) |
Persistent levels in the 30–300 range (confirmed in ≥2 of 3 tests) indicate incipient nephropathy.
📈 Interpretation of Results
Albumin Level | Implication |
|---|---|
< 30 mg/24hr | Normal kidney function |
30–300 mg/24hr | Early diabetic/hypertensive nephropathy |
> 300 mg/24hr | Advanced renal damage; possible proteinuria |
🧠 Associated Organs & Conditions
System/Organ | Conditions |
|---|---|
Kidneys | Diabetic nephropathy, hypertensive nephrosclerosis, CKD |
Endocrine | Diabetes mellitus |
Cardiovascular | Heart disease risk (strongly associated) |
Others | Preeclampsia, lupus nephritis, glomerulonephritis |
🔄 Related / Follow-Up Tests
- Serum Creatinine and eGFR – kidney function
- Urinalysis (routine) – for protein, RBCs, casts
- Spot Urine Albumin-to-Creatinine Ratio (ACR) – for monitoring
- Blood Pressure Monitoring
- HbA1c – diabetes control
- Lipid Profile – cardiovascular risk
✅ Fasting Required?
Test | Fasting Required |
|---|---|
Microalbumin 24-Hour | ❌ No |
Important instructions:
✔ Avoid intense physical activity
✔ Avoid sample collection during fever, menstruation, or UTI
✔ Follow exact timing and complete the 24-hour collection accurately
📝 Summary Table
Parameter | Details |
|---|---|
What | Measures total urinary albumin over 24 hours |
Why | Detect early kidney damage in diabetes/hypertension |
Normal Range | < 30 mg/24 hr |
Microalbuminuria | 30–300 mg/24 hr – early kidney disease |
Macroalbuminuria | > 300 mg/24 hr – advanced nephropathy |
Associated Conditions | CKD, diabetes, hypertension, cardiovascular risk |
Follow-up Tests | ACR, creatinine, eGFR, HbA1c, BP, lipid profile |
Fasting Required | ❌ No |
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