Microfilaria Antibody
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Helps in the early diagnosis of filarial infection before microfilariae are visible in the blood
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🧪 What is the Microfilaria Antibody Test?
The Microfilaria Antibody Test detects IgG or IgM antibodies against filarial parasites, such as Wuchereria bancrofti or Brugia malayi, which cause lymphatic filariasis.
- It is a serological test (usually ELISA or IFA-based)
- Helps in the early diagnosis of filarial infection before microfilariae are visible in the blood
❓ Why is the Test Done?
To:
- Diagnose lymphatic filariasis (especially in early or asymptomatic cases)
- Investigate symptoms like lymphadenopathy, elephantiasis, or recurrent fevers
- Support diagnosis when night blood smear is negative
- Screen exposed populations in endemic areas
📊 Normal Range & Interpretation
Result | Interpretation |
|---|---|
Negative | No detectable antibodies to filarial parasites |
Positive | Indicates exposure or current/past infection |
Antibody levels may remain elevated after successful treatment or past exposure
📈 Interpretation of Results
Antibody Type | Implication |
|---|---|
IgM Positive | Recent or acute filarial infection |
IgG Positive | Ongoing or past infection; may persist for years |
Both Positive | Active or chronic filarial disease |
False Positives | Possible in cross-reactivity with other parasitic infections |
🧠 Associated Organs & Conditions
System/Organ | Associated Conditions |
|---|---|
Lymphatic system | Lymphatic filariasis, elephantiasis |
Immune system | Chronic eosinophilia, tropical pulmonary eosinophilia |
Skin and soft tissue | Lymphedema, scrotal swelling, hydrocele |
Respiratory | Cough, wheeze (TPE-related) |
🔄 Related / Follow-Up Tests
- Peripheral Blood Smear (best collected at night)
- Circulating Filarial Antigen (CFA) test – more specific for W. bancrofti
- Eosinophil Count – usually elevated
- IgE levels
- Ultrasound (lymphatic obstruction, hydrocele)
- PCR for filarial DNA
✅ Fasting Required?
Test | Fasting Required |
|---|---|
Microfilaria Antibody | ❌ Not required |
📝 Summary Table
Parameter | Details |
|---|---|
What | Detects antibodies against filarial parasites |
Why | Diagnose or screen for lymphatic filariasis |
Normal Range | Negative for filarial antibodies |
Positive Result | Suggests active or prior filarial infection |
Associated Conditions | Lymphatic filariasis, elephantiasis, tropical pulmonary eosinophilia |
Follow-up Tests | Blood smear, CFA, eosinophils, PCR, imaging |
Fasting Required | ❌ No |
How our test process works!
