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Protein creatinine ratio (Spot)

Unit Test
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Report in 24Hrs

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At Home

Details

Key marker of kidney filtration function (GFR); elevated in renal impairment.

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🧪 What is Protein Creatinine Ratio (PCR) – Spot Urine Test?

The Protein Creatinine Ratio (PCR) in a spot urine sample measures the amount of protein excreted in urine relative to creatinine, providing an estimate of daily protein loss without the need for a 24-hour urine collection. It is a convenient and reliable marker of proteinuria.

❓ Why is the Test Done?

To:

  • Detect and quantify proteinuria, an important sign of kidney damage
  • Monitor patients with diabetes, hypertension, or glomerular diseases
  • Assess the severity and progression of chronic kidney disease (CKD)
  • Guide therapy and monitor response to treatment

📊 Normal Range

PCR Value

Interpretation

< 0.15 mg protein/mg creatinine (or < 150 mg/g)

Normal protein excretion

0.15 – 0.5 mg/mg creatinine (or 150–500 mg/g)

Mild proteinuria

> 0.5 mg/mg creatinine (or > 500 mg/g)

Significant proteinuria, likely nephropathy

Note: Units vary by lab (mg/mg or mg/g). Confirm with lab reference.

📈 Interpretation of Results

PCR Level

Clinical Significance

Normal

No significant proteinuria

Mildly elevated

Early kidney damage or transient proteinuria

Markedly elevated

Persistent proteinuria, suggests glomerular disease

🧠 Associated Conditions

Organ/System

Conditions

Kidneys

Diabetic nephropathy, glomerulonephritis, hypertension-related kidney disease

Cardiovascular

Proteinuria as a marker of endothelial dysfunction

Systemic Diseases

Lupus nephritis, vasculitis

🔄 Related / Follow-Up Tests

  • 24-hour urine protein estimation – confirmatory in some cases
  • Serum creatinine and eGFR – evaluate kidney function
  • Urinalysis and microscopy – detect red cells, casts
  • Blood pressure monitoring
  • Autoimmune serology if systemic disease suspected

✅ Fasting Required?

Test

Fasting Required

Protein Creatinine Ratio (Spot)

No

📝 Summary Table

Parameter

Details

What

Ratio of protein to creatinine in a spot urine sample

Why

Screen and monitor proteinuria and kidney damage

Normal Range

< 0.15 mg/mg or < 150 mg/g

Elevated Levels

Indicate kidney damage or glomerular disease

Associated Conditions

Diabetic nephropathy, glomerulonephritis, hypertension-related kidney disease

Follow-up Tests

24-hour urine protein, serum creatinine, urinalysis

Fasting Required

❌ No

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