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Scrotum biopsy - Medium Biopsy 1-3 cm

Biopsy
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Report in 288Hrs

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No Fasting Required

Details

Tissue biopsy of scrotum.

₹370₹529

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Scrotum Biopsy - Medium Biopsy 1-3 cm

  • Why is it done?
    • To obtain tissue samples from scrotal lesions or abnormalities for microscopic examination and diagnosis
    • To differentiate between benign and malignant lesions, including suspected scrotal cancers (melanoma, squamous cell carcinoma, basal cell carcinoma)
    • To evaluate persistent skin lesions, ulcers, nodules, or masses in the scrotal region that do not respond to conservative treatment
    • To diagnose infectious conditions such as fungal infections, bacterial infections, or sexually transmitted infections affecting the scrotum
    • To identify inflammatory skin conditions affecting the scrotal area, such as dermatitis or psoriasis
    • Typically performed when physical examination reveals suspicious lesions, unexplained growths, or changes requiring definitive diagnosis
  • Normal Range
    • Negative/Normal Result: Benign tissue with normal histological architecture; absence of malignant cells or pathogenic organisms; normal skin and subcutaneous tissue without inflammation
    • Units of Measurement: Histopathological examination; specimen size 1-3 cm; tissue staining with hematoxylin and eosin (H&E) and special stains as needed
    • Interpretation Categories: Normal tissue (benign), benign lesion with specific diagnosis, malignant neoplasm, infectious agent identified, inflammatory condition, or inadequate specimen
    • What Normal Means: No evidence of malignancy, no significant infection, and no pathological condition requiring treatment; lesion is benign and typically does not require aggressive intervention
    • What Abnormal Means: Presence of malignant cells, identification of infectious organisms, significant inflammation, or other pathological findings requiring specific treatment
  • Interpretation
    • Benign Lesions: Seborrheic keratosis, epidermoid cysts, lipomas, angiomas, or other non-cancerous growths; may require no further treatment or simple removal for cosmetic reasons
    • Malignant Findings: Melanoma, squamous cell carcinoma, basal cell carcinoma, or other skin cancers; requires immediate specialist consultation and staging/treatment planning
    • Infectious Agents: Fungal (candida, tinea), bacterial, viral, or parasitic organisms; results guide appropriate antimicrobial therapy selection
    • Inflammatory Conditions: Dermatitis, psoriasis, lichen planus, or other inflammatory dermatoses; identified patterns help determine appropriate topical or systemic therapy
    • Factors Affecting Results: Specimen adequacy and handling, tissue preservation, staining technique quality, pathologist expertise, clinical history provided, and whether multiple areas were sampled
    • Clinical Significance of Patterns: Atypia or dysplasia indicates increased malignant potential; clear margins in cancer specimens are favorable; presence of vascular invasion or lymph node involvement affects prognosis and staging
  • Associated Organs
    • Primary Organ System: Integumentary system (skin) and reproductive system (external genitalia)
    • Common Conditions Associated with Abnormal Results: Scrotal cancer (melanoma, squamous cell carcinoma), genital herpes, genital warts, tinea cruris, candidiasis, bacterial infections, erythema, psoriasis, lichen sclerosus, and systemic diseases affecting skin
    • Diseases This Test Helps Diagnose: Melanoma and other skin malignancies, sexually transmitted infections, fungal infections, syphilis, tuberculosis verrucosa cutis, leprosy (Hansen's disease), and systemic inflammatory conditions
    • Potential Complications/Risks Associated with Abnormal Results: Cancer progression requiring systemic chemotherapy or surgical intervention; spread of infection to adjacent tissues or systemic circulation; sexual transmission of infectious agents; psychological impact of cancer diagnosis; need for monitoring for metastatic disease
    • Related Anatomical Considerations: Scrotal skin is thin and highly vascularized; proximity to testis and epididymis requires careful biopsy technique; lymphatic drainage to inguinal nodes may be relevant for cancer staging
  • Follow-up Tests
    • If Malignancy Detected: Sentinel lymph node biopsy, staging CT or PET-CT imaging, complete blood count, liver function tests, lactate dehydrogenase (LDH) level, chest X-ray, and possible tumor markers
    • If Infection Identified: Gram stain, culture and sensitivity testing, fungal culture, viral serology (HSV, HPV), rapid plasma reagin (RPR) or VDRL for syphilis, HIV testing, and antibiotic/antifungal sensitivity panels
    • If Inflammatory Condition: Direct immunofluorescence (if autoimmune suspected), ANA panel, complement levels, or referral to rheumatology for systemic disease evaluation
    • If Specimen Inadequate: Repeat biopsy with adequate sampling, possibly from different site or using alternative technique
    • Monitoring Frequency: For malignancy: every 3-6 months initially for stage-appropriate monitoring; for infection: post-treatment testing to confirm cure; for benign lesions: routine follow-up as clinically indicated
    • Related Complementary Tests: Dermatoscopy, ultrasound of scrotum, dermoscopy examination, immunohistochemistry staining, flow cytometry, genetic/molecular testing (BRAF, KIT mutations in melanoma), and photographic documentation for serial monitoring
  • Fasting Required?
    • Fasting Required: No
    • Pre-Procedure Preparation: Bathe or shower on day of procedure; wear comfortable, loose clothing that allows easy access to the biopsy site; avoid strenuous activity 24 hours before procedure
    • Medications: Discontinue aspirin and NSAIDs 3-5 days before biopsy (increases bleeding risk); avoid warfarin/anticoagulants if possible (consult prescribing physician); continue other routine medications unless specifically instructed otherwise
    • Special Instructions: Skin around biopsy site will be cleaned and sterilized; local anesthetic will be administered; patient should remain still during procedure; bring written list of current medications and allergies; arrange transportation as sedation may be used; wear clean, supportive underwear after procedure
    • Post-Procedure Care: Keep site clean and dry; avoid bathing for 24-48 hours; wear loose clothing to prevent irritation; observe for signs of infection (increased redness, warmth, discharge, fever); pain typically resolves within 1-2 weeks; avoid sexual activity for 1-2 weeks; mild analgesics may be used as directed

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