Serum Insulin PP after 75gm Glucose load
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Assesses insulin levels in blood; used in diagnosing insulin resistance and metabolic syndrome.
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🧪 What is Serum Insulin PP after 75 gm Glucose Load?
This test measures the level of insulin in the blood 2 hours after ingestion of 75 grams of glucose. It evaluates how the pancreas responds to a glucose challenge, reflecting insulin secretion and sensitivity.
❓ Why is the Test Done?
To:
- Assess insulin resistance and beta-cell function
- Diagnose and monitor prediabetes and Type 2 diabetes
- Evaluate metabolic syndrome and polycystic ovarian syndrome (PCOS)
- Investigate causes of hypoglycemia or reactive hypoglycemia
- Guide treatment decisions related to glucose metabolism disorders
📊 Normal Range
Insulin Level (µIU/mL) | Interpretation |
|---|---|
< 50 | Normal insulin response |
50 – 80 | Possible hyperinsulinemia/insulin resistance |
> 80 | Significant insulin resistance |
Reference ranges may vary by laboratory and method.
📈 Interpretation of Results
Result | Clinical Significance |
|---|---|
Low Insulin | Possible beta-cell failure (Type 1 diabetes) |
Normal Insulin | Adequate pancreatic response |
High Insulin | Insulin resistance, early Type 2 diabetes, PCOS |
Very High Insulin | Severe insulin resistance or hyperinsulinemic state |
🧠 Associated Conditions
Condition | Details |
|---|---|
Type 2 diabetes | Insulin resistance and relative insulin deficiency |
Prediabetes | Early metabolic dysfunction |
Polycystic ovarian syndrome (PCOS) | Often associated with hyperinsulinemia |
Hypoglycemia | Investigate reactive or insulinoma-related causes |
🔄 Related / Follow-Up Tests
- Fasting Insulin
- Fasting and postprandial glucose
- HbA1c
- HOMA-IR (Homeostatic Model Assessment for Insulin Resistance)
- C-peptide
- Lipid profile
✅ Fasting Required?
Test | Fasting Required |
|---|---|
Insulin PP after 75 gm glucose load | ✅ Initial fasting required before glucose load; sample taken 2 hours after ingestion |
📝 Summary Table
Parameter | Details |
|---|---|
What | Measures insulin 2 hours after 75 gm oral glucose load |
Why | Assess insulin secretion, insulin resistance, beta-cell function |
Normal Range | < 50 µIU/mL |
High Levels | Insulin resistance, PCOS, early Type 2 diabetes |
Low Levels | Beta-cell failure (Type 1 diabetes) |
Associated Conditions | Diabetes, prediabetes, PCOS, hypoglycemia |
Follow-up Tests | Fasting insulin, glucose, HbA1c, HOMA-IR |
Fasting Required | ✅ Yes, fasting before glucose load, then sample 2 hours post ingestion |
How our test process works!
