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Sugar (Glucose) Post Prandial
Diabetes
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Fasting Required
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Measures blood sugar levels to diagnose diabetes
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Sugar (Glucose) Post Prandial - Comprehensive Medical Test Guide
- Why is it done?
- Measures blood glucose level 2 hours after consuming a meal or glucose drink to assess how the body processes and manages blood sugar after food intake
- Screens for and diagnoses diabetes mellitus, particularly Type 2 diabetes and gestational diabetes
- Evaluates glucose tolerance and pancreatic beta cell function in response to dietary carbohydrates
- Monitors glucose control in patients already diagnosed with diabetes
- Identifies individuals at risk for metabolic syndrome and cardiovascular disease
- Typically ordered during routine health screening, pregnancy assessment, or when symptoms of hyperglycemia are present (excessive thirst, frequent urination, fatigue)
- Normal Range
- Normal Range: Less than 140 mg/dL (7.8 mmol/L) for non-diabetic individuals
- Impaired Glucose Tolerance (IGT): 140-199 mg/dL (7.8-11.0 mmol/L) - indicates prediabetes
- Diabetes Mellitus: 200 mg/dL (11.1 mmol/L) or higher - diagnostic for diabetes
- Gestational Diabetes Screening: Normal <140 mg/dL, Abnormal ≥140 mg/dL during pregnancy glucose tolerance test
- Units of Measurement: mg/dL (milligrams per deciliter) or mmol/L (millimoles per liter)
- Interpretation: Normal results indicate efficient glucose metabolism and good insulin response. Elevated results suggest impaired glucose tolerance or diabetes requiring further evaluation and lifestyle modification or medical intervention
- Interpretation
- Results <140 mg/dL (Normal): Indicates normal glucose regulation and adequate insulin secretion and sensitivity
- Results 140-199 mg/dL (Impaired Glucose Tolerance): Prediabetic state with decreased insulin sensitivity; significant risk for developing Type 2 diabetes within 5-10 years without intervention
- Results ≥200 mg/dL (Diabetic): Diagnostic of diabetes mellitus; indicates significant impairment in glucose metabolism and insulin function; warrants immediate medical management
- Factors Affecting Results: Stress, infection, illness, menstrual cycle, physical activity level, dietary composition (high glycemic index foods), medications (corticosteroids, beta-blockers), smoking, caffeine consumption, and obesity
- Clinical Significance: Post-prandial glucose testing is more sensitive than fasting glucose for detecting impaired glucose tolerance and early diabetes; consistently elevated values indicate poor metabolic control and increased cardiovascular and microvascular complication risks
- Variability in Interpretation: Results may vary based on meal composition, portion size, and individual metabolic responses; ethnic and age-related variations exist
- Associated Organs
- Primary Organ Systems: Endocrine system (pancreatic beta cells), liver (glucose production and regulation), muscles (glucose uptake and utilization)
- Associated Conditions with Elevated Post-Prandial Glucose: Type 2 Diabetes Mellitus, Type 1 Diabetes Mellitus, Gestational Diabetes Mellitus, Insulin Resistance, Metabolic Syndrome, Prediabetes
- Secondary Conditions Associated with Elevated Glucose: Polycystic Ovary Syndrome (PCOS), Cushing's Syndrome, Hyperthyroidism, Pancreatic disease, Liver cirrhosis, Hemochromatosis, Acromegaly
- Potential Complications of Prolonged Elevated Post-Prandial Glucose: Diabetic retinopathy (eye damage), Diabetic nephropathy (kidney disease), Diabetic neuropathy (nerve damage), Coronary artery disease, Cerebrovascular disease, Diabetic foot ulcers, Accelerated atherosclerosis
- Target Organs for Chronic Hyperglycemia Damage: Kidneys, Eyes, Peripheral nerves, Heart and blood vessels, Brain
- Follow-up Tests
- If Results are Abnormal: Fasting Blood Glucose (FBG) to assess baseline glucose levels
- Hemoglobin A1C (HbA1C) to evaluate average glucose control over 2-3 months
- Oral Glucose Tolerance Test (OGTT) for comprehensive glucose response evaluation
- Fasting Insulin or C-peptide to assess pancreatic insulin production
- Lipid panel (cholesterol, triglycerides, HDL, LDL) to assess cardiovascular risk
- Liver function tests and renal function tests (creatinine, eGFR) to monitor diabetes complications
- Urinalysis and microalbumin testing to detect early kidney damage
- For Diabetic Patients - Routine Monitoring: HbA1C every 3-6 months (target <7% for most adults)
- Home glucose monitoring as prescribed by healthcare provider
- Annual comprehensive metabolic panel and renal/liver function assessment
- Annual eye examinations and foot assessments
- For Gestational Diabetes Screening Abnormalities: 3-hour Glucose Tolerance Test for confirmatory diagnosis
- Fetal ultrasound monitoring and maternal glycemic control assessment
- Fasting Required?
- Fasting Required: NO - This is a non-fasting test
- Pre-Test Instructions: Patient should eat a normal meal or consume standard glucose drink (75g glucose load for diagnostic OGTT)
- Blood sample collection should occur EXACTLY 2 hours after meal consumption or glucose drink ingestion
- Patient should refrain from eating or drinking (except water) during the 2-hour waiting period
- Medication Instructions: Continue regular medications unless specifically instructed otherwise by physician
- Inform provider of medications that may affect glucose metabolism (corticosteroids, thiazide diuretics, beta-blockers, oral contraceptives)
- Additional Preparation Requirements: Maintain normal physical activity level in days preceding test
- Minimize stress and ensure adequate sleep night before testing
- Avoid smoking and excess caffeine on test day
- Wear comfortable, loose-fitting clothing for easy blood draw access
- Inform phlebotomist of any previous difficulties with blood draws or vasovagal responses
How our test process works!

