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🧪 What is Syphilis TP Test?

The Syphilis TP test detects antibodies against Treponema pallidum, the bacterium that causes syphilis. It is a treponemal test, used to confirm syphilis infection by identifying specific antibodies.

❓ Why is the Test Done?

To:

Diagnose syphilis infection (current or past)
Confirm positive screening results from non-treponemal tests (e.g., VDRL, RPR)
Screen at-risk populations (pregnant women, sexually transmitted infection clinics)
Monitor treatment response (though titers remain positive for life)

📊 Normal Range / Interpretation

Result	Interpretation
Negative	No detectable Treponema antibodies; no infection
Positive	Presence of antibodies indicating syphilis exposure or infection

📈 Clinical Significance

Result	Implication
Positive TP antibody	Past or current syphilis infection; remains positive lifelong
Negative TP antibody	No evidence of infection or very early infection

🧠 Associated Conditions

Condition	Details
Syphilis infection	Primary, secondary, latent, or tertiary stages
Congenital syphilis	Transplacental infection of fetus
Neurosyphilis	Central nervous system involvement

🔄 Related / Follow-Up Tests

Non-treponemal tests (VDRL, RPR) for disease activity and treatment monitoring
Dark field microscopy for direct visualization of the organism (rare)
CSF analysis for suspected neurosyphilis
HIV testing due to co-infection risk

✅ Fasting Required?

Test	Fasting Required
Syphilis TP Test	❌ No

📝 Summary Table

Parameter	Details
What	Detects antibodies specific to Treponema pallidum
Why	Diagnose and confirm syphilis infection
Normal Result	Negative; no antibodies detected
Positive Result	Indicates current or past syphilis infection
Associated Conditions	Syphilis stages, congenital syphilis, neurosyphilis
Follow-up Tests	VDRL, RPR, CSF analysis, HIV testing
Fasting Required	❌ No

Syphilis TP

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