Thyroid Profile (5 Parameters)
Profile
5 parameters
Report in 24Hrs
At Home
Fasting Required
Details
TFTs may be requested if a patient is thought to suffer from hyperthyroidism or hypothyroidism, or to monitor the effectiveness of either thyroid-suppression or hormone replacement therapy, Free T3, Free T4, Total T3, Total T4, TSH
₹4999₹6250
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Test Overview
Thyroid Hormone Panel – Complete Explanation
Test Fasting Required? Produced By What It Measures Why It’s Important Normal Range
- Free T3 (Triiodothyronine – Unbound Form)
- Fasting: Recommended (for standardization)
- Produced By: Thyroid and peripheral conversion from T4
- Measures: Active, unbound T3 available to tissues
- High: Hyperthyroidism (T3 toxicosis), Graves’ disease
- Low: Hypothyroidism, chronic illness (NTIS)
- Normal Range: 2.3 – 4.2 pg/mL
- Most active thyroid hormone at the tissue level
- Free T4 (Thyroxine – Unbound Form)
- Fasting: Yes
- Produced By: Thyroid gland
- Measures: Active, unbound T4 in blood
- High: Hyperthyroidism, thyroid hormone resistance
- Low: Hypothyroidism, pituitary or hypothalamic disorders
- Normal Range: 0.8 – 1.8 ng/dL
- Preferred marker for evaluating thyroid function, especially during pregnancy or when binding proteins are altered
- Total
T3
- Fasting: Yes
- Produced By: Thyroid and liver (T4 → T3 conversion)
- Measures: Both bound and free forms of T3
- High: Hyperthyroidism, T3 thyrotoxicosis
- Low: Hypothyroidism, severe illness
- Normal Range: 80 – 200 ng/dL
- Useful when free T3 is not available or in borderline cases
- Total
T4
- Fasting: Yes
- Produced By: Thyroid
- Measures: Total amount of T4 (free + bound to proteins)
- High: Hyperthyroidism, increased binding proteins (pregnancy, estrogen use)
- Low: Hypothyroidism, low protein states
- 5 – 12 µg/dL
- Influenced by binding proteins; best interpreted alongside Free T4 and TSH
- TSH (Thyroid Stimulating Hormone)
- Fasting: Yes (especially in the morning)
- Produced By: Pituitary gland
- Measures: Pituitary’s signal to the thyroid to make hormones
- High: Hypothyroidism (thyroid not producing enough T3/T4)
- Low: Hyperthyroidism (too much hormone feedback)
- Normal Range: 0.4 – 4.0 mIU/L (may vary slightly by lab)
- Primary screening test for thyroid disorders
How These Tests Work Together
| TSH | Free T3/T4 | Likely Diagnosis |
|---|---|---|
| ↑ | ↓ | Primary Hypothyroidism |
| ↓ | ↑ | Primary Hyperthyroidism |
| ↓ | ↓ | Secondary Hypothyroidism (pituitary problem) |
| ↑ | Normal | Subclinical Hypothyroidism |
| ↓ | Normal | Subclinical Hyperthyroidism |
When to Order All 5 Tests
- Persistent or ambiguous thyroid symptoms
- Nodules, goiter, or irregular thyroid medications
- Thyroid function in pregnancy or on estrogen therapy
- Suspected thyroid hormone resistance or binding protein abnormalities
Recommended Add-On Tests
| Condition | Add-On Tests |
|---|---|
| Autoimmune thyroid issues | Anti-TPO, Anti-Tg antibodies |
| Hyperthyroidism workup | TRAb (TSH receptor antibodies) |
| Thyroid nodules | Thyroid Ultrasound, Fine Needle Aspiration |
| Hypothyroid with fatigue | Cortisol, Vitamin D, B12 |
How our test process works!
