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🧪 What is Total IgE?

Total Immunoglobulin E (IgE) measures the overall concentration of IgE antibodies in the blood. IgE is an antibody involved primarily in allergic reactions and defense against parasitic infections.

❓ Why is the Test Done?

To:

Evaluate and support the diagnosis of allergic diseases such as asthma, allergic rhinitis, eczema, food allergies
Assess parasitic infections causing elevated IgE
Monitor response to allergy treatments
Investigate unexplained eosinophilia or chronic urticaria

📊 Normal Range

Total IgE Level	Reference Range
Adults	< 100 – 150 IU/mL (varies by lab)
Children	May be higher; age-dependent

📈 Interpretation of Results

Result	Clinical Implication
Elevated IgE	Suggests allergic sensitization, parasitic infection, some immunodeficiency syndromes
Normal or low IgE	Less likely allergic etiology

🧠 Associated Conditions

Condition	Details
Atopic diseases	Asthma, allergic rhinitis, atopic dermatitis
Parasitic infections	Helminth infections causing immune activation
Immunodeficiency disorders	Hyper-IgE syndrome and others
Other conditions	Some malignancies, autoimmune diseases

🔄 Related / Follow-Up Tests

Specific IgE testing – identify allergen sensitivities
Complete blood count (CBC) – check eosinophil count
Skin prick testing – assess allergic reactions
Parasitic serologies

✅ Fasting Required?

Test	Fasting Required
Total IgE	❌ No

📝 Summary Table

Parameter	Details
What	Measures total IgE antibodies in blood
Why	Evaluate allergies and parasitic infections
Normal Range	< 100–150 IU/mL (varies)
Elevated Levels	Allergies, parasitic infections, immunodeficiencies
Associated Conditions	Asthma, atopy, helminthiasis, hyper-IgE syndrome
Follow-up Tests	Specific IgE, CBC, skin prick tests
Fasting Required	❌ No

Total IGE

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