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🧪 What is Total Leucocyte Count?

The Total Leucocyte Count (TLC) measures the total number of white blood cells (WBCs) in a given volume of blood. Leukocytes are essential components of the immune system, defending the body against infections and foreign substances.

❓ Why is the Test Done?

To:

Detect and monitor infections (bacterial, viral, fungal)
Evaluate immune system disorders
Diagnose and monitor leukemia and other hematological diseases
Assess inflammatory or allergic conditions
Monitor response to treatment for infections or hematological disorders

📊 Normal Range

Total Leucocyte Count	Reference Range
Adults	4,000 – 11,000 cells per microliter (4.0 – 11.0 × 10³/µL)

Reference ranges may vary by lab.

📈 Interpretation of Results

Result	Clinical Significance
Leukocytosis (high TLC)	Infection, inflammation, stress, leukemia
Leukopenia (low TLC)	Bone marrow suppression, viral infections, autoimmune diseases

🧠 Associated Conditions

Condition	Details
Bacterial infections	Often cause elevated TLC
Viral infections	May cause normal or low TLC
Leukemia	Markedly elevated or abnormal WBC counts
Autoimmune diseases	May cause leukopenia
Bone marrow disorders	Aplastic anemia, myelodysplastic syndrome

🔄 Related / Follow-Up Tests

Differential Leucocyte Count (DLC)
Peripheral blood smear
Bone marrow biopsy (if hematological malignancy suspected)
Inflammatory markers (CRP, ESR)

✅ Fasting Required?

Test	Fasting Required
Total Leucocyte Count	❌ No

📝 Summary Table

Parameter	Details
What	Total white blood cell count in blood
Why	Diagnose infections, inflammation, hematologic diseases
Normal Range	4,000 – 11,000 /µL
High Count	Infection, inflammation, leukemia
Low Count	Bone marrow suppression, viral infections, autoimmune diseases
Associated Conditions	Infections, leukemia, autoimmune diseases, marrow disorders
Follow-up Tests	Differential count, blood smear, bone marrow biopsy
Fasting Required	❌ No

Total Leucocytes Count

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