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🧪 What is Total Triiodothyronine (T3)?

Total T3 measures the total amount of triiodothyronine hormone in the blood, including both protein-bound and free forms. T3 is a thyroid hormone responsible for regulating metabolism, growth, and development and is the active form of thyroid hormone in the body.

❓ Why is the Test Done?

To:

Evaluate thyroid function, especially in cases of suspected hyperthyroidism
Diagnose and monitor thyroid disorders like thyrotoxicosis or hypothyroidism
Assess thyroid status when total T4 and TSH results are inconclusive
Monitor response to thyroid hormone therapy

📊 Normal Range

Total T3 Level	Reference Range
Adults	80 – 200 ng/dL (1.23 – 3.08 nmol/L)

Reference ranges may vary slightly by lab and method.

📈 Interpretation of Results

Result	Clinical Significance
High Total T3	Hyperthyroidism, thyroid hormone overdose
Low Total T3	Hypothyroidism, non-thyroidal illness ("sick euthyroid")
Normal Total T3	Normal thyroid function or compensated disorders

🧠 Associated Conditions

Condition	Details
Hyperthyroidism	Graves’ disease, toxic adenoma
Hypothyroidism	Primary hypothyroidism, thyroid hormone deficiency
Euthyroid sick syndrome	Low T3 due to systemic illness without thyroid disease

🔄 Related / Follow-Up Tests

Thyroid Stimulating Hormone (TSH)
Total and Free Thyroxine (T4)
Free Triiodothyronine (Free T3)
Thyroid autoantibodies

✅ Fasting Required?

Test	Fasting Required
Total Triiodothyronine (T3)	❌ No

📝 Summary Table

Parameter	Details
What	Measures total triiodothyronine hormone (bound + free)
Why	Assess thyroid function, especially in hyperthyroidism
Normal Range	80–200 ng/dL
High Levels	Hyperthyroidism, thyroid hormone excess
Low Levels	Hypothyroidism, euthyroid sick syndrome
Associated Conditions	Thyroid dysfunction, systemic illness
Follow-up Tests	TSH, T4, Free T3, thyroid antibodies
Fasting Required	❌ No

Total Triiodothyronine (T3)

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