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🧪 What is Toxoplasma gondii IgG?

The Toxoplasma gondii IgG test detects IgG antibodies against Toxoplasma gondii, indicating past or chronic infection. IgG antibodies develop several weeks after initial infection and typically remain detectable lifelong, providing immunity.

❓ Why is the Test Done?

To:

Determine past exposure or immunity to Toxoplasma gondii
Assess risk of congenital toxoplasmosis during pregnancy
Evaluate immunocompromised patients for latent infection risk
Support diagnosis of toxoplasmosis when correlated with IgM and clinical features

📊 Normal Range / Interpretation

Result	Interpretation
Negative	No prior exposure or very recent infection
Positive	Past or chronic infection with immunity

📈 Interpretation of Results

Result	Clinical Significance
Positive IgG only	Past infection, likely immune
Positive IgG + Positive IgM	Recent or active infection (requires further evaluation)
Negative IgG + Positive IgM	Early infection or false positive IgM

🧠 Associated Conditions

Condition	Details
Past toxoplasma infection	Usually asymptomatic, immunity developed
Congenital toxoplasmosis	Risk if acute infection during pregnancy
Immunosuppression	Reactivation risk in latent infection

🔄 Related / Follow-Up Tests

Toxoplasma IgM antibodies – to assess recent infection
IgG avidity test – distinguish recent vs past infection
PCR for Toxoplasma DNA – detect active infection
Imaging for CNS involvement if symptomatic

✅ Fasting Required?

Test	Fasting Required
Toxoplasma gondii IgG	❌ No

📝 Summary Table

Parameter	Details
What	IgG antibodies indicating past or chronic toxoplasma infection
Why	Determine immunity or past exposure
Normal Result	Negative; no prior exposure
Positive Result	Past infection with immunity
Associated Conditions	Latent toxoplasmosis, immunity status
Follow-up Tests	IgM, IgG avidity, PCR
Fasting Required	❌ No

TOXOPLASMA GONDII - IgG

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