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🧪 What is Typhi Dot IgG?

The Typhi Dot IgG test is a rapid serological assay that detects IgG antibodies against Salmonella Typhi, the bacterium responsible for typhoid fever. The presence of IgG antibodies generally indicates past exposure or chronic/recovered infection.

❓ Why is the Test Done?

To:

Diagnose typhoid fever, especially in the later stages or in cases of chronic/recovered infection
Assess immune response after vaccination or past infection
Support clinical diagnosis when blood cultures are negative or unavailable

📊 Normal Range / Interpretation

Result	Interpretation
Negative	No detectable IgG antibodies; no past infection
Positive	Presence of IgG antibodies indicating past or ongoing infection

📈 Interpretation of Results

Result	Clinical Significance
Positive IgG	Suggests previous exposure or immunity to S. Typhi; may persist long-term
Negative IgG	No evidence of past infection or immunity

🧠 Associated Conditions

Condition	Details
Typhoid fever	Acute or past infection by Salmonella Typhi
Chronic carrier state	Persistent bacterial carriage after acute illness
Immunity post vaccination	Presence of antibodies following vaccination

🔄 Related / Follow-Up Tests

Typhi Dot IgM – detects recent or acute infection
Blood culture – gold standard for diagnosis
Widal test – traditional serological test
PCR for Salmonella DNA – molecular diagnosis

✅ Fasting Required?

Test	Fasting Required
Typhi Dot IgG	❌ No

📝 Summary Table

Parameter	Details
What	Detects IgG antibodies against Salmonella Typhi
Why	Diagnose past or chronic typhoid infection
Normal Result	Negative; no past infection
Positive Result	Indicates past exposure or immunity
Associated Conditions	Typhoid fever, chronic carrier, post-vaccination immunity
Follow-up Tests	Typhi Dot IgM, blood culture, Widal test
Fasting Required	❌ No