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🧪 What is Typhi Dot IgM?

The Typhi Dot IgM test is a rapid serological assay that detects IgM antibodies against Salmonella Typhi, the causative agent of typhoid fever. The presence of IgM antibodies typically indicates a recent or acute infection.

❓ Why is the Test Done?

To:

Diagnose acute or recent typhoid fever
Support clinical diagnosis when blood cultures are negative or unavailable
Guide timely treatment decisions in febrile patients with suspected typhoid

📊 Normal Range / Interpretation

Result	Interpretation
Negative	No detectable IgM antibodies; no recent infection
Positive	Presence of IgM antibodies indicating recent or acute infection

📈 Interpretation of Results

Result	Clinical Significance
Positive IgM	Suggests recent or acute typhoid infection
Negative IgM	No recent infection; past infection not ruled out

🧠 Associated Conditions

Condition	Details
Acute typhoid fever	Febrile illness caused by Salmonella Typhi
Other Salmonella infections	May rarely cross-react in some cases

🔄 Related / Follow-Up Tests

Typhi Dot IgG – indicates past infection or immunity
Blood culture – gold standard for diagnosis
Widal test – traditional serological test
PCR for Salmonella DNA – molecular diagnosis

✅ Fasting Required?

Test	Fasting Required
Typhi Dot IgM	❌ No

📝 Summary Table

Parameter	Details
What	Detects IgM antibodies against Salmonella Typhi
Why	Diagnose recent or acute typhoid infection
Normal Result	Negative; no recent infection
Positive Result	Indicates acute or recent typhoid fever
Associated Conditions	Typhoid fever, acute Salmonella infection
Follow-up Tests	Typhi Dot IgG, blood culture, Widal test
Fasting Required	❌ No