Uric Acid
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Quantifies uric acid levels; elevated in gout or kidney stones.
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🧪 What is Uric Acid?
Uric acid is a waste product formed from the breakdown of purines, which are substances found in many foods and also produced by the body. It is normally excreted by the kidneys through urine.
❓ Why is the Test Done?
To:
- Diagnose and monitor gout and hyperuricemia
- Evaluate causes of kidney stones
- Assess renal function
- Monitor patients on medications affecting uric acid levels
📊 Normal Range
Uric Acid Level | Reference Range |
|---|---|
Men | 3.5 – 7.2 mg/dL (208 – 428 µmol/L) |
Women | 2.6 – 6.0 mg/dL (155 – 357 µmol/L) |
Ranges may vary slightly by lab.
📈 Interpretation of Results
Result | Clinical Significance |
|---|---|
High uric acid | Gout, kidney stones, renal failure, increased cell turnover (e.g., leukemia) |
Low uric acid | Rare; may be seen in Wilson’s disease, SIADH, or after chemotherapy |
🧠 Associated Conditions
Condition | Details |
|---|---|
Gout | Deposition of urate crystals causing joint inflammation |
Kidney stones | Uric acid stones formation |
Renal failure | Decreased excretion leading to elevated levels |
Metabolic syndrome | Associated with hyperuricemia |
🔄 Related / Follow-Up Tests
- Renal function tests (urea, creatinine)
- Serum electrolytes
- Joint fluid analysis (for gout crystals)
- 24-hour urine uric acid
✅ Fasting Required?
Test | Fasting Required |
|---|---|
Uric Acid | ❌ No |
📝 Summary Table
Parameter | Details |
|---|---|
What | Measures serum uric acid level |
Why | Diagnose gout, kidney stones, monitor renal function |
Normal Range | Men: 3.5–7.2 mg/dL; Women: 2.6–6.0 mg/dL |
High Levels | Gout, kidney stones, renal failure |
Low Levels | Rare; certain metabolic disorders |
Associated Conditions | Gout, kidney stones, metabolic syndrome, renal disease |
Follow-up Tests | Renal function, joint fluid analysis |
Fasting Required | ❌ No |
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